Safe ImageTM products represent a new and safe class of nucleic acid stains for the visualization of double-stranded DNA (dsDNA), singlestranded DNA (ssDNA), and RNA in agarose and polyacrylamide gels. The dyes have the capability to bind DNA and are thus developed to replace toxic Ethidium Bromide (EB, a potent mutagen), commonly used in gel electrophoresis for visualization of nucleic acids. Safe Image™ products are non-carcinogenic by the Ames-test. The results are negative in both the mouse marrow chromophilous erythrocyte micronucleus and mouse spermary spermatocyte chromosomal aberration tests. Safe ImageTM Fire Red are used the same way as Ethidium Bromide in agarose and polyacrylamide gel electrophoresis.