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ADAMTS4 (ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 4, ADAMTS4)

Short Description: This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The enzyme encoded by this gene lacks a C-terminal TS motif. It is responsible for the degradation of aggrecan, a major proteoglycan of cartilage, and brevican, a brain-specific extracellular matrix protein. The cleavage of aggrecan and brevican suggests key roles of this enzyme in arthritic disease and in the central nervous system, potentially, in the progression of glioma. [provided by RefSeq, Jul 2008].
More information related to gene ADAMTS4.

Products related to ADAMTS4 Gene:

51 results

OriGene kn409226 gRNA + Cas9 GEEN Mammalian Expression Vector pCas-Guide Ampicillin U6 Promoter Myc-DYKDDDDK Tag Transient
Type:
gRNA + Cas9
Application:
Genome Editing with Engineered Nucleases
Gene:
ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 4 (ADAMTS4)
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pCas-Guide
Resistance Gene:
Ampicillin
Promoter:
U6 Promoter, Enhanced CMV Promoter
Fusion Tag:
Myc-DYKDDDDK Tag
Expression:
Transient
Catalog No. ABIN3245377
$1,640.43
Plus shipping costs $50.00
1 kit
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  • Type
    • Plasmid
    • Primer
  • Supplier
    • antibodies-online
    • OriGene
    • GenScript
    • ProteoGenix
  • Reactivity
    • Human
    • Mouse
    • Rat
  • Application
    • Protein Expression (PExp)
    • Genome Editing with Engineered Nucleases (GEEN)
    • Cloning (Clon)
    • RNA Interference (RNAi)
  • Conjugate
    • Un-conjugated
    • GFP tag
    • His tag
    • Myc-DYKDDDDK Tag
    • HA tag
    • His-GST
    • His-MBP
    • DYKDDDDK Tag
  • Vector Backbone
    • pLenti-U6-sgRNA-PGK-Neo
    • pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
    • pCMV6-Entry
    • pORF
    • pPB-His-GST
    • pPB-His-MBP
    • pPB-N-His
    • pPM-C-HA
    • pPM-C-His
    • pCas-Guide
    • pGFP-C-shLenti
    • pGFP-V-RS
    • pLenti-C-Myc-DDK
    • pLenti-C-mGFP
    • pRS
    • pCMV6-AC-GFP
    • pCMV6-XL5
    • pDONR223
    • pcDNA3.1+C-(K)-DYK
  • Vector
    • Lentiviral Vector
    • Mammalian Expression Vector
    • Bacterial Expression Vector
    • Retroviral Vector
    • Cloning Vector
    • Gateway Cloning Vector
  • Insert
    • cDNA
    • ORF
    • gRNA + Cas9
    • gRNA
    • shRNA
  • Type of Oligonucleotide
    • siRNA Oligo
  • Bacterial Resistance
    • Kanamycin
    • Ampicillin
    • Chloramphenicol
    • Spectinomycin
  • Expression Type
    • Transient
    • Stable
  • Selectable Marker
    • Neomycin
    • Puromycin
  • Promoter
    • U6 Promoter
    • CMV Promoter
    • T7 Promoter
    • PGK Promoter
    • SFFV Promoter
    • Enhanced CMV Promoter
  • Format
    • Lyophilized
    • Liquid
    • Viral Particles

Synonyms and alternative names related to ADAMTS4

  • a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 4 (Adamts4)
  • ADAM metallopeptidase with thrombospondin type 1 motif 4 (ADAMTS4)
  • ADAM metallopeptidase with thrombospondin type 1 motif, 4 (Adamts4)
  • ADAM metallopeptidase with thrombospondin type 1 motif 4 (Adamts4)
  • 3830423K05
  • ADAM-TS4
  • ADAMTS-2
  • ADAMTS-4
  • ADAMTS4
  • ADMP-1
  • mKIAA0688

Gene-IDs for different species

Protein level used designations for ADAMTS4

  • A disintegrin and metalloproteinase with thrombospondin motifs 4
  • ADAM-TS 4
  • ADAMTS-4
  • a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 4
  • aggrecanase-1
  • ADAM-TS4
  • Aggrecanase
  • a disintegrin and metallopeptidase with thrombospondin motifs 4
  • a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 4
  • ADMP-1
  • ADAM metallopeptidase with thrombospondin type 1 motif, 4
  • A disintegrin and metalloproteinase with thrombospondin motifs 4-like
  • disintegrin and metalloproteinase with thrombospondin motifs 2
  • a disintegrin and metalloproteinase with thrombospondin motifs 4
Other products related to ADAMTS4 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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