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ADD3 (Adducin 3 (Gamma), ADD3)
Short Description: Adducins are heteromeric proteins composed of different subunits referred to as adducin alpha, beta and gamma. The three subunits are encoded by distinct genes and belong to a family of membrane skeletal proteins involved in the assembly of spectrin-actin network in erythrocytes and at sites of cell-cell contact in epithelial tissues. While adducins alpha and gamma are ubiquitously expressed, the expression of adducin beta is restricted to brain and hematopoietic tissues. Adducin, originally purified from human erythrocytes, was found to be a heterodimer of adducins alpha and beta. Polymorphisms resulting in amino acid substitutions in these two subunits have been associated with the regulation of blood pressure in an animal model of hypertension. Heterodimers consisting of alpha and gamma subunits have also been described. Structurally, each subunit is comprised of two distinct domains. The amino-terminal region is protease resistant and globular in shape, while the carboxy-terminal region is protease sensitive. The latter contains multiple phosphorylation sites for protein kinase C, the binding site for calmodulin, and is required for association with spectrin and actin. Alternatively spliced adducin gamma transcripts encoding different isoforms have been described. The functions of the different isoforms are not known. [provided by RefSeq, Jul 2008].
More information related to gene ADD3.
Products related to ADD3 Gene:
Recommended next Filters:
cDNA
PExp
Mammalian Expression Vector
pPM-C-His
Kanamycin
CMV Promoter
His tag
Stable
Type:
cDNA
Application:
Protein Expression
Gene:
Adducin 3 (Gamma) (ADD3)
NCBI Accession:
NM_001164103
Species:
Rat
Vector type:
Mammalian Expression Vector
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
His tag
Expression:
Stable, Transient
Catalog No. ABIN4497527
$2,612.50
Plus shipping costs $50.00
Delivery in 21 to 32 Business Days
cDNA
PExp
Mammalian Expression Vector
pPM-C-His
Kanamycin
CMV Promoter
His tag
Stable
Type:
cDNA
Application:
Protein Expression
Gene:
Adducin 3 (Gamma) (ADD3)
NCBI Accession:
NM_031552
Species:
Rat
Vector type:
Mammalian Expression Vector
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
His tag
Expression:
Stable, Transient
Catalog No. ABIN4497528
$2,612.50
Plus shipping costs $50.00
Delivery in 21 to 32 Business Days
ORF
Clon
Gateway Cloning Vector
pDONR223
Spectinomycin
unconjugated
Type:
ORF
Application:
Cloning
Gene:
Adducin 3 (Gamma) (ADD3)
Gene ID:
120 (Human, ADD3)
Vector type:
Gateway Cloning Vector
Resistance Gene:
Spectinomycin
Catalog No. ABIN5321759
$235.38
Plus shipping costs $50.00
Delivery in 15 to 19 Business Days
ORF
PExp
Mammalian Expression Vector
pcDNA3.1+C-(K)-DYK
Ampicillin
CMV Promoter
DYKDDDDK Tag
Transient
Type:
ORF
Application:
Protein Expression
Gene:
Adducin 3 (Gamma) (ADD3)
NCBI Accession:
NM_016824
Gene ID:
120 (Human, ADD3)
Vector type:
Mammalian Expression Vector
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
DYKDDDDK Tag
Expression:
Transient, Stable
Catalog No. ABIN4941751
$379.00
Plus shipping costs $50.00
Delivery in 4 to 7 Business Days
ORF
PExp
Mammalian Expression Vector
pcDNA3.1+C-(K)-DYK
Ampicillin
CMV Promoter
DYKDDDDK Tag
Transient
Type:
ORF
Application:
Protein Expression
Gene:
Adducin 3 (Gamma) (ADD3)
NCBI Accession:
NM_019903
Gene ID:
120 (Human, ADD3)
Vector type:
Mammalian Expression Vector
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
DYKDDDDK Tag
Expression:
Transient, Stable
Catalog No. ABIN4944740
$559.00
Plus shipping costs $50.00
Delivery in 31 to 32 Business Days
OriGene sr419349
RNAi
ADD3
Species: Mouse
HPLC purified
Application:
RNA Interference
Gene:
Adducin 3 (Gamma)
Species:
Mouse
Purification:
HPLC purified
Catalog No. ABIN3266861
$512.82
Plus shipping costs $50.00
Delivery in 16 to 17 Business Days
OriGene sr507536
RNAi
ADD3
Species: Rat
HPLC purified
Application:
RNA Interference
Gene:
Adducin 3 (Gamma)
Species:
Rat
Purification:
HPLC purified
Catalog No. ABIN3356998
$512.82
Plus shipping costs $50.00
Delivery in 16 to 17 Business Days
OriGene sr300082
RNAi
ADD3
Species: Human
HPLC purified
Application:
RNA Interference
Gene:
Adducin 3 (Gamma)
Species:
Human
Purification:
HPLC purified
Catalog No. ABIN3339878
$512.82
Plus shipping costs $50.00
Delivery in 4 to 9 Business Days
OriGene rn207822
cDNA
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
Enhanced CMV Promoter
unconjugated
Transient
Type:
cDNA
Application:
Protein Expression
Gene:
Adducin 3 (Gamma) (ADD3)
NCBI Accession:
NM_031552,NP_113740
Species:
Rat
Vector type:
Mammalian Expression Vector
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
Enhanced CMV Promoter
Expression:
Transient
Catalog No. ABIN3308962
$610.83
Plus shipping costs $50.00
Delivery in 4 to 9 Business Days
OriGene rc209129
ORF
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
CMV Promoter
Myc-DYKDDDDK Tag
Transient
Type:
ORF
Application:
Protein Expression
Gene:
Adducin 3 (Gamma) (ADD3)
NCBI Accession:
NM_016824,NP_058432
Species:
Human
Vector type:
Mammalian Expression Vector
Resistance Gene:
Kanamycin
Promoter:
CMV Promoter
Fusion Tag:
Myc-DYKDDDDK Tag
Expression:
Transient
Catalog No. ABIN5371960
$639.54
Plus shipping costs $50.00
Delivery in 8 to 11 Business Days
Synonyms and alternative names related to ADD3
adducin 3 (gamma) (ADD3)
adducin 3 (add3)
adducin 3 (ADD3)
adducin 3 L homeolog (add3.L)
adducin 3 (gamma) (Add3)
adducin 3 (Add3)
add3
ADD3
ADDL
AI463285
DKFZp459E0630
gamma-adducin
MGC89418
R75380
Gene-IDs for different species
Protein level used designations for ADD3
gamma-adducin
adducin 3 (gamma)
adducin 3 gamma
gamma-adducin-like
adducin-like protein 70
cytoskeletal protein
potein kinase C binding protein 35H
protein kinase C-binding protein 35H
Other products related to ADD3 such as antibodies, ELISA kits and high-purity proteins are available on our partner website
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