ALOX5 (Arachidonate 5-Lipoxygenase, ALOX5)
Short Description: This gene encodes a member of the lipoxygenase gene family and plays a dual role in the synthesis of leukotrienes from arachidonic acid. The encoded protein, which is expressed specifically in bone marrow-derived cells, catalyzes the conversion of arachidonic acid to 5(S)-hydroperoxy-6-trans-8,11,14-cis-eicosatetraenoic acid, and further to the allylic epoxide 5(S)-trans-7,9-trans-11,14-cis-eicosatetrenoic acid (leukotriene A4). Leukotrienes are important mediators of a number of inflammatory and allergic conditions. Mutations in the promoter region of this gene lead to a diminished response to antileukotriene drugs used in the treatment of asthma and may also be associated with atherosclerosis and several cancers. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012].
More information related to gene ALOX5.
More information related to gene ALOX5.
Products related to ALOX5 Gene:
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71 results
OriGene sr504708
RNAi
ALOX5
Species: Rat
HPLC purified
- Application:
- RNA Interference
- Gene:
- Arachidonate 5-Lipoxygenase
- Species:
- Rat
- Purification:
- HPLC purified
Catalog No. ABIN3354571
$512.82
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Will be delivered in 16 Business Days
OriGene rc217259
ORF
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
CMV Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Arachidonate 5-Lipoxygenase (ALOX5)
- NCBI Accession:
- NM_000698,NP_000689
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-Entry
- Resistance Gene:
- Kanamycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN5392217
$583.11
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 8 to 10 Business Days
OriGene sc316253
cDNA
PExp
Mammalian Expression Vector
pCMV6-XL4
Ampicillin
Enhanced CMV Promoter
unconjugated
Transient
1
- Type:
- cDNA
- Application:
- Protein Expression
- Gene:
- Arachidonate 5-Lipoxygenase (ALOX5)
- NCBI Accession:
- NM_000698,NP_000689
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-XL4
- Resistance Gene:
- Ampicillin
- Promoter:
- Enhanced CMV Promoter, T7 Promoter
- Expression:
- Transient
Catalog No. ABIN3376995
$611.82
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 4 to 8 Business Days
OriGene rc233017
ORF
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
CMV Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Arachidonate 5-Lipoxygenase (ALOX5)
- NCBI Accession:
- NM_001256154,NP_001243083
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-Entry
- Resistance Gene:
- Kanamycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN5392218
$625.68
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Will be delivered in 21 Business Days
OriGene rc233049
ORF
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
CMV Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Arachidonate 5-Lipoxygenase (ALOX5)
- NCBI Accession:
- NM_001256153,NP_001243082
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-Entry
- Resistance Gene:
- Kanamycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN5392219
$650.43
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Will be delivered in 21 Business Days
OriGene rr204994
ORF
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
CMV Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Arachidonate 5-Lipoxygenase (ALOX5)
- NCBI Accession:
- NM_012822,NP_036954
- Species:
- Rat
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-Entry
- Resistance Gene:
- Kanamycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN5392220
$668.25
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Will be delivered in 36 Business Days
OriGene rn204994
cDNA
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
Enhanced CMV Promoter
unconjugated
Transient
1
- Type:
- cDNA
- Application:
- Protein Expression
- Gene:
- Arachidonate 5-Lipoxygenase (ALOX5)
- NCBI Accession:
- NM_012822,NP_036954
- Species:
- Rat
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-Entry
- Resistance Gene:
- Kanamycin
- Selection Marker:
- Neomycin
- Promoter:
- Enhanced CMV Promoter
- Expression:
- Transient
Catalog No. ABIN3309513
$669.24
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Will be delivered in 36 Business Days
OriGene mc220311
cDNA
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
Enhanced CMV Promoter
unconjugated
Transient
1
- Type:
- cDNA
- Application:
- Protein Expression
- Gene:
- Arachidonate 5-Lipoxygenase (ALOX5)
- NCBI Accession:
- NM_009662,NP_033792
- Species:
- Mouse
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-Entry
- Resistance Gene:
- Kanamycin
- Selection Marker:
- Neomycin
- Promoter:
- Enhanced CMV Promoter
- Expression:
- Transient
Catalog No. ABIN3309512
$673.20
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Will be delivered in 31 Business Days
OriGene tg500083
shRNA
RNAi
Retroviral Vector
pGFP-V-RS
Kanamycin
U6 Promoter
GFP tag
Transient
1
- Type:
- shRNA
- Application:
- RNA Interference
- Gene:
- Arachidonate 5-Lipoxygenase (ALOX5)
- Species:
- Mouse
- Vector type:
- Retroviral Vector
- Vector backbone:
- pGFP-V-RS
- Resistance Gene:
- Kanamycin
- Selection Marker:
- Puromycin
- Promoter:
- U6 Promoter
- Fusion Tag:
- GFP tag
- Expression:
- Transient, Stable
Catalog No. ABIN3682133
$707.85
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Will be delivered in 16 Business Days
OriGene tg314820
shRNA
RNAi
Retroviral Vector
pGFP-V-RS
Kanamycin
U6 Promoter
GFP tag
Transient
1
- Type:
- shRNA
- Application:
- RNA Interference
- Gene:
- Arachidonate 5-Lipoxygenase (ALOX5)
- Species:
- Human
- Vector type:
- Retroviral Vector
- Vector backbone:
- pGFP-V-RS
- Resistance Gene:
- Kanamycin
- Selection Marker:
- Puromycin
- Promoter:
- U6 Promoter
- Fusion Tag:
- GFP tag
- Expression:
- Transient, Stable
Catalog No. ABIN3739652
$707.85
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Will be delivered in 16 Business Days
Synonyms and alternative names related to ALOX5
- arachidonate 5-lipoxygenase (ALOX5)
- arachidonate 5-lipoxygenase (Alox5)
- arachidonate 5-lipoxygenase a (alox5a)
- arachidonate 5-lipoxygenase (AFUA_4G02770)
- arachidonate 5-lipoxygenase (AOR_1_1362014)
- Arachidonate 5-lipoxygenase (lox5)
- 5-LO
- 5-LOX
- 5LO
- 5LPG
- 5LX
- AI850497
- F730011J02
- LOG5
- lox5
- LOX5A
- si:dkey-194n13.2
Gene-IDs for different species
Protein level used designations for ALOX5
- LOX-5
- arachidonic 5-lipoxygenase alpha-10 isoform
- arachidonic 5-lipoxygenase delta-10-13 isoform
- arachidonic 5-lipoxygenase delta-13 isoform
- arachidonic 5-lipoxygenase delta-p10 isoform
- arachidonic acid 5-lipoxygenase
- leukotriene A4 synthase
- 5-lipoxygenase
- 5 - Lipoxygenase
- 5-LO
- LOX2
- arachidonate 5-lipoxygenase
- Arachidonate 5-lipoxygenase
Proteomics products related to ALOX5 Gene
Other products related to ALOX5 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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