ALOX5 (Arachidonate 5-Lipoxygenase, ALOX5)
Short Description: This gene encodes a member of the lipoxygenase gene family and plays a dual role in the synthesis of leukotrienes from arachidonic acid. The encoded protein, which is expressed specifically in bone marrow-derived cells, catalyzes the conversion of arachidonic acid to 5(S)-hydroperoxy-6-trans-8,11,14-cis-eicosatetraenoic acid, and further to the allylic epoxide 5(S)-trans-7,9-trans-11,14-cis-eicosatetrenoic acid (leukotriene A4). Leukotrienes are important mediators of a number of inflammatory and allergic conditions. Mutations in the promoter region of this gene lead to a diminished response to antileukotriene drugs used in the treatment of asthma and may also be associated with atherosclerosis and several cancers. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012].
More information related to gene ALOX5.
More information related to gene ALOX5.
Products related to ALOX5 Gene:
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OriGene kn417259
gRNA + Cas9
GEEN
Mammalian Expression Vector
pCas-Guide
Ampicillin
U6 Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- gRNA + Cas9
- Application:
- Genome Editing with Engineered Nucleases
- Gene:
- Arachidonate 5-Lipoxygenase (ALOX5)
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCas-Guide
- Resistance Gene:
- Ampicillin
- Promoter:
- U6 Promoter, Enhanced CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN3245962
$1,640.43
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Will be delivered in 21 Business Days
Synonyms and alternative names related to ALOX5
- arachidonate 5-lipoxygenase (ALOX5)
- arachidonate 5-lipoxygenase (Alox5)
- arachidonate 5-lipoxygenase a (alox5a)
- arachidonate 5-lipoxygenase (AFUA_4G02770)
- arachidonate 5-lipoxygenase (AOR_1_1362014)
- Arachidonate 5-lipoxygenase (lox5)
- 5-LO
- 5-LOX
- 5LO
- 5LPG
- 5LX
- AI850497
- F730011J02
- LOG5
- lox5
- LOX5A
- si:dkey-194n13.2
Gene-IDs for different species
Protein level used designations for ALOX5
- LOX-5
- arachidonic 5-lipoxygenase alpha-10 isoform
- arachidonic 5-lipoxygenase delta-10-13 isoform
- arachidonic 5-lipoxygenase delta-13 isoform
- arachidonic 5-lipoxygenase delta-p10 isoform
- arachidonic acid 5-lipoxygenase
- leukotriene A4 synthase
- 5-lipoxygenase
- 5 - Lipoxygenase
- 5-LO
- LOX2
- arachidonate 5-lipoxygenase
- Arachidonate 5-lipoxygenase
Proteomics products related to ALOX5 Gene
Other products related to ALOX5 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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