Short Description: Annexin VII is a member of the annexin family of calcium-dependent phospholipid binding proteins.The Annexin VII gene contains 14 exons and spans approximately 34 kb of DNA. An alternatively spliced cassette exon results in two mRNA transcripts of 2.0 and 2.4 kb which are predicted to generate two protein isoforms differing in their N-terminal domain. The alternative splicing event is tissue specific and the mRNA containing the cassette exon is prevalent in brain, heart and skeletal muscle. The transcripts also differ in their 3'-non coding regions by the use of two alternative poly(A) signals. Annexin VII encodes a protein with a molecular weight of approximately 51 kDa with a unique, highly hydrophobic N-terminal domain of 167 amino acids and a conserved C-terminal region of 299 amino acids. The latter domain is composed of alternating hydrophobic and hydrophilic segments. Structural analysis of the protein suggests that Annexin VII is a membrane binding protein with diverse properties, including voltage-sensitive calcium channel activity, ion selectivity and membrane fusion. [provided by RefSeq, Jul 2008]. More information related to gene Annexin VII.
Synonyms and alternative names related to Annexin VII
annexin A7 (ANXA7)
annexin A7 (Anxa7)
annexin VII (anxa7)
annexin A7 (anxa7)
annexin A7 S homeolog (anxa7.S)
annexin A7 (PTRG_02166)
annexin A7 (BRAFLDRAFT_231082)
annexin A7 (PAAG_00136)
annexin A7 (MCYG_04180)
annexin A7 (VDBG_06328)
annexin A7 (MGYG_02426)
AI265384
AI316497
ANX7
Anx7
anxa7
ANXA7
MGC76267
MGC82023
MGC83033
SNX
SYNEXIN
synexin
Gene-IDs for different species
Protein level used designations for Annexin VII
annexin VII
annexin-7
annexin A7
synexin
annexin A7-like
Proteomics products related to Annexin VII Gene
Other products related to Annexin VII such as antibodies, ELISA kits and high-purity proteins are available on our partner website
antibodies-online.com