AVPR2 (Arginine Vasopressin Receptor 2, AVPR2)
Short Description: This gene encodes the vasopressin receptor, type 2, also known as the V2 receptor, which belongs to the seven-transmembrane-domain G protein-coupled receptor (GPCR) superfamily, and couples to Gs thus stimulating adenylate cyclase. The subfamily that includes the V2 receptor, the V1a and V1b vasopressin receptors, the oxytocin receptor, and isotocin and mesotocin receptors in non-mammals, is well conserved, though several members signal via other G proteins. All bind similar cyclic nonapeptide hormones. The V2 receptor is expressed in the kidney tubule, predominantly in the distal convoluted tubule and collecting ducts, where its primary property is to respond to the pituitary hormone arginine vasopressin (AVP) by stimulating mechanisms that concentrate the urine and maintain water homeostasis in the organism. When the function of this gene is lost, the disease Nephrogenic Diabetes Insipidus (NDI) results. The V2 receptor is also expressed outside the kidney although its tissue localization is uncertain. When these 'extrarenal receptors' are stimulated by infusion of a V2 selective agonist (dDAVP), a variety of clotting factors are released into the bloodstream. The physiologic importance of this property is not known - its absence does not appear to be detrimental in NDI patients. The gene expression has also been described in fetal lung tissue and lung cancer associated with alternative splicing. [provided by RefSeq, Jul 2008].
More information related to gene AVPR2.
More information related to gene AVPR2.
Products related to AVPR2 Gene:
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61 results
OriGene kn410914
gRNA + Cas9
GEEN
Mammalian Expression Vector
pCas-Guide
Ampicillin
U6 Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- gRNA + Cas9
- Application:
- Genome Editing with Engineered Nucleases
- Gene:
- Arginine Vasopressin Receptor 2 (AVPR2)
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCas-Guide
- Resistance Gene:
- Ampicillin
- Promoter:
- U6 Promoter, Enhanced CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN3247428
$1,640.43
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 21 to 22 Business Days
Synonyms and alternative names related to AVPR2
- arginine vasopressin receptor 2 (AVPR2)
- arginine vasopressin receptor 2 (Avpr2)
- ADHR
- AVPR2
- DI1
- DIR
- DIR3
- ND1
- NDI
- V2R
- VPV2R
Gene-IDs for different species
Protein level used designations for AVPR2
- vasopressin V2 receptor
- arginine vasopressin receptor 2
- AVPR V2
- antidiuretic hormone receptor
- renal-type arginine vasopressin receptor
- V-2 lysine vasopressin receptor
- V2R
- arginine vasopressin receptor 2 (nephrogenic diabetes insipidus)
- nephrogenic diabetes insipidus
- Vasopressin receptor V2
Proteomics products related to AVPR2 Gene
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