BCR (Breakpoint Cluster Region, BCR)
Short Description: A reciprocal translocation between chromosomes 22 and 9 produces the Philadelphia chromosome, which is often found in patients with chronic myelogenous leukemia. The chromosome 22 breakpoint for this translocation is located within the BCR gene. The translocation produces a fusion protein which is encoded by sequence from both BCR and ABL, the gene at the chromosome 9 breakpoint. Although the BCR-ABL fusion protein has been extensively studied, the function of the normal BCR gene product is not clear. The protein has serine/threonine kinase activity and is a GTPase-activating protein for p21rac. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
More information related to gene BCR.
More information related to gene BCR.
Products related to BCR Gene:
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OriGene kn411635
gRNA + Cas9
GEEN
Mammalian Expression Vector
pCas-Guide
Ampicillin
U6 Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- gRNA + Cas9
- Application:
- Genome Editing with Engineered Nucleases
- Gene:
- Breakpoint Cluster Region (BCR)
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCas-Guide
- Resistance Gene:
- Ampicillin
- Promoter:
- U6 Promoter, Enhanced CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN3247818
$1,640.43
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 21 to 22 Business Days
Synonyms and alternative names related to BCR
- breakpoint cluster region (bcr)
- BCR, RhoGEF and GTPase activating protein (BCR)
- BCR, RhoGEF and GTPase activating protein (bcr)
- breakpoint cluster region (Bcr)
- BCR, RhoGEF and GTPase activating protein (Bcr)
- 5133400C09Rik
- AI561783
- AI853148
- ALL
- BCR
- BCR1
- CML
- D22S11
- D22S662
- mKIAA3017
- PHL
- si:dkey-83d9.7
- zK83D9.7
Gene-IDs for different species
Protein level used designations for BCR
- breakpoint cluster region
- breakpoint cluster region protein-like
- BCR/FGFR1 chimera protein
- FGFR1/BCR chimera protein
- breakpoint cluster region protein
- renal carcinoma antigen NY-REN-26
- breakpoint cluster region homolog
Proteomics products related to BCR Gene
Other products related to BCR such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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