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BRCA2 (Breast Cancer 2, Early Onset, BRCA2)

Short Description: Inherited mutations in BRCA1 and this gene, BRCA2, confer increased lifetime risk of developing breast or ovarian cancer. Both BRCA1 and BRCA2 are involved in maintenance of genome stability, specifically the homologous recombination pathway for double-strand DNA repair. The BRCA2 protein contains several copies of a 70 aa motif called the BRC motif, and these motifs mediate binding to the RAD51 recombinase which functions in DNA repair. BRCA2 is considered a tumor suppressor gene, as tumors with BRCA2 mutations generally exhibit loss of heterozygosity (LOH) of the wild-type allele. [provided by RefSeq, Dec 2008].
More information related to gene BRCA2.

Products related to BRCA2 Gene:

51 results

OriGene tr314439 shRNA RNAi Retroviral Vector pRS Ampicillin U6 Promoter unconjugated Transient
Type:
shRNA
Application:
RNA Interference
Gene:
Breast Cancer 2, Early Onset (BRCA2)
Species:
Human
Vector type:
Retroviral Vector
Vector backbone:
pRS
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter
Expression:
Transient, Stable
Catalog No. ABIN3656370
$874.17
Plus shipping costs $50.00
1 kit
Shipping to: United States
Delivery in 4 to 9 Business Days
OriGene tr500223 shRNA RNAi Retroviral Vector pRS Ampicillin U6 Promoter unconjugated Transient
Type:
shRNA
Application:
RNA Interference
Gene:
Breast Cancer 2, Early Onset (BRCA2)
Species:
Mouse
Vector type:
Retroviral Vector
Vector backbone:
pRS
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter
Expression:
Transient, Stable
Catalog No. ABIN3532574
$874.17
Plus shipping costs $50.00
1 kit
Shipping to: United States
Delivery in 16 to 17 Business Days
OriGene tl314439 shRNA RNAi Lentiviral Vector pGFP-C-shLenti Chloramphenicol U6 Promoter GFP tag Transient
Type:
shRNA
Application:
RNA Interference
Gene:
Breast Cancer 2, Early Onset (BRCA2)
Species:
Human
Vector type:
Lentiviral Vector
Vector backbone:
pGFP-C-shLenti
Resistance Gene:
Chloramphenicol
Selection Marker:
Puromycin
Promoter:
U6 Promoter
Fusion Tag:
GFP tag
Expression:
Transient, Stable
Catalog No. ABIN3759610
$1,002.87
Plus shipping costs $50.00
1 kit
Shipping to: United States
Delivery in 16 to 17 Business Days
OriGene tl500223 shRNA RNAi Lentiviral Vector pGFP-C-shLenti Chloramphenicol U6 Promoter GFP tag Transient
Type:
shRNA
Application:
RNA Interference
Gene:
Breast Cancer 2, Early Onset (BRCA2)
Species:
Mouse
Vector type:
Lentiviral Vector
Vector backbone:
pGFP-C-shLenti
Resistance Gene:
Chloramphenicol
Selection Marker:
Puromycin
Promoter:
U6 Promoter
Fusion Tag:
GFP tag
Expression:
Transient, Stable
Catalog No. ABIN3701973
$1,002.87
Plus shipping costs $50.00
1 kit
Shipping to: United States
Delivery in 16 to 17 Business Days
OriGene kn302249 gRNA + Cas9 GEEN Mammalian Expression Vector pCas-Guide Ampicillin U6 Promoter Myc-DYKDDDDK Tag Transient
Type:
gRNA + Cas9
Application:
Genome Editing with Engineered Nucleases
Gene:
Breast Cancer 2, Early Onset (BRCA2)
Species:
Mouse
Vector type:
Mammalian Expression Vector
Vector backbone:
pCas-Guide
Resistance Gene:
Ampicillin
Promoter:
U6 Promoter, Enhanced CMV Promoter
Fusion Tag:
Myc-DYKDDDDK Tag
Expression:
Transient
Catalog No. ABIN3248077
$1,640.43
Plus shipping costs $50.00
1 kit
Shipping to: United States
Delivery in 21 to 22 Business Days
OriGene kn213464 gRNA + Cas9 GEEN Mammalian Expression Vector pCas-Guide Ampicillin U6 Promoter Myc-DYKDDDDK Tag Transient
Type:
gRNA + Cas9
Application:
Genome Editing with Engineered Nucleases
Gene:
Breast Cancer 2, Early Onset (BRCA2)
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pCas-Guide
Resistance Gene:
Ampicillin
Promoter:
U6 Promoter, Enhanced CMV Promoter
Fusion Tag:
Myc-DYKDDDDK Tag
Expression:
Transient
Catalog No. ABIN3248076
$1,640.43
Plus shipping costs $50.00
1 kit
Shipping to: United States
Delivery in 21 to 22 Business Days
OriGene rn211711 cDNA PExp Mammalian Expression Vector pCMV6-Entry Kanamycin Enhanced CMV Promoter unconjugated Transient
Type:
cDNA
Application:
Protein Expression
Gene:
Breast Cancer 2, Early Onset (BRCA2)
NCBI Accession:
NM_031542,NP_113730
Species:
Rat
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-Entry
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
Enhanced CMV Promoter
Expression:
Transient
Catalog No. ABIN3293926
$2,895.75
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 71 to 72 Business Days
OriGene mc229768 cDNA PExp Mammalian Expression Vector pCMV6-Entry Kanamycin Enhanced CMV Promoter unconjugated Transient
Type:
cDNA
Application:
Protein Expression
Gene:
Breast Cancer 2, Early Onset (BRCA2)
NCBI Accession:
NM_001081001,NP_001074470
Species:
Mouse
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-Entry
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
Enhanced CMV Promoter
Expression:
Transient
Catalog No. ABIN3293925
$2,938.32
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 61 to 62 Business Days
OriGene rc213464 ORF PExp Mammalian Expression Vector pCMV6-Entry Kanamycin CMV Promoter Myc-DYKDDDDK Tag Transient
Type:
ORF
Application:
Protein Expression
Gene:
Breast Cancer 2, Early Onset (BRCA2)
NCBI Accession:
NM_000059,NP_000050
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-Entry
Resistance Gene:
Kanamycin
Promoter:
CMV Promoter
Fusion Tag:
Myc-DYKDDDDK Tag
Expression:
Transient
Catalog No. ABIN5377589
$4,035.24
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 41 to 42 Business Days
OriGene rg213464 ORF PExp Mammalian Expression Vector pCMV6-AC-GFP Ampicillin CMV Promoter GFP tag Stable
Type:
ORF
Application:
Protein Expression
Gene:
Breast Cancer 2, Early Onset (BRCA2)
NCBI Accession:
NM_000059,NP_000050
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-AC-GFP
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
GFP tag
Expression:
Stable, Transient
Catalog No. ABIN5377588
$4,233.24
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 41 to 42 Business Days
  • Type
    • Plasmid
    • Primer
  • Supplier
    • antibodies-online
    • OriGene
  • Reactivity
    • Mouse
    • Human
    • Rat
  • Application
    • Protein Expression (PExp)
    • Genome Editing with Engineered Nucleases (GEEN)
    • Cloning (Clon)
    • RNA Interference (RNAi)
  • Conjugate
    • Un-conjugated
    • His tag
    • GFP tag
    • HA tag
    • His-GST
    • His-MBP
    • Myc-DYKDDDDK Tag
  • Vector Backbone
    • pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
    • pLenti-U6-sgRNA-PGK-Neo
    • pCMV6-Entry
    • pORF
    • pPB-His-GST
    • pPB-His-MBP
    • pPB-N-His
    • pPM-C-HA
    • pPM-C-His
    • pCas-Guide
    • pGFP-C-shLenti
    • pGFP-V-RS
    • pRS
    • pCMV6-AC-GFP
  • Vector
    • Lentiviral Vector
    • Mammalian Expression Vector
    • Bacterial Expression Vector
    • Retroviral Vector
    • Cloning Vector
  • Insert
    • cDNA
    • gRNA + Cas9
    • gRNA
    • shRNA
    • ORF
  • Type of Oligonucleotide
    • siRNA Oligo
  • Bacterial Resistance
    • Ampicillin
    • Kanamycin
    • Spectinomycin
    • Chloramphenicol
  • Expression Type
    • Transient
    • Stable
  • Selectable Marker
    • Neomycin
    • Puromycin
  • Promoter
    • U6 Promoter
    • SFFV Promoter
    • T7 Promoter
    • CMV Promoter
    • PGK Promoter
    • Enhanced CMV Promoter
  • Format
    • Liquid
    • Viral Particles
    • Lyophilized

Synonyms and alternative names related to BRCA2

  • BRCA2, DNA repair associated (BRCA2)
  • Breast cancer 2, early onset homolog (Brca2)
  • BRCA2, DNA repair associated (Brca2)
  • breast cancer 2, early onset (brca2)
  • breast cancer 2, early onset (LOC584780)
  • BRCA2, DNA repair associated (brca2)
  • breast cancer 2, early onset (Brca2)
  • 30169
  • AI256696
  • AW045498
  • BcDNA:SD25109
  • brca2
  • BRCA2
  • BRCC2
  • brcc2
  • BROVCA2
  • brovca2
  • CG13583
  • CG13584
  • CG30169
  • dmbrca2
  • Dmel\\CG30169
  • FACD
  • facd
  • FAD
  • fad
  • FAD1
  • fad1
  • FANCB
  • fancb
  • FANCD
  • FANCD1
  • fancd1
  • Fancd1
  • GLM3
  • PNCA2
  • RAB163

Gene-IDs for different species

Protein level used designations for BRCA2

  • BRCA1/BRCA2-containing complex, subunit 2
  • breast and ovarian cancer susceptibility gene, early onset
  • breast cancer 2 tumor suppressor
  • breast cancer type 2 susceptibility protein
  • fanconi anemia group D1 protein
  • truncated breast and ovarian cancer susceptibility protein 2
  • breast cancer 2, early onset homolog
  • CG30169-PA
  • Brca2-PA
  • breast cancer 2, mutation 1, University of Wisconsin-Madison
  • breast cancer susceptibility protein 2
  • breast cancer type 2 susceptibility protein homolog
  • fanconi anemia group D1 protein homolog
  • breast and ovarian cancer susceptibility protein 2
  • breast cancer 2, early onset
  • breast cancer type 2 susceptibility protein-like
Other products related to BRCA2 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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