BRCA2 (Breast Cancer 2, Early Onset, BRCA2)
Short Description: Inherited mutations in BRCA1 and this gene, BRCA2, confer increased lifetime risk of developing breast or ovarian cancer. Both BRCA1 and BRCA2 are involved in maintenance of genome stability, specifically the homologous recombination pathway for double-strand DNA repair. The BRCA2 protein contains several copies of a 70 aa motif called the BRC motif, and these motifs mediate binding to the RAD51 recombinase which functions in DNA repair. BRCA2 is considered a tumor suppressor gene, as tumors with BRCA2 mutations generally exhibit loss of heterozygosity (LOH) of the wild-type allele. [provided by RefSeq, Dec 2008].
More information related to gene BRCA2.
More information related to gene BRCA2.
Products related to BRCA2 Gene:
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OriGene mc225477
cDNA
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
Enhanced CMV Promoter
unconjugated
Transient
1
- Type:
- cDNA
- Application:
- Protein Expression
- Gene:
- Breast Cancer 2, Early Onset (BRCA2)
- NCBI Accession:
- NM_009765,NP_033895
- Species:
- Mouse
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-Entry
- Resistance Gene:
- Kanamycin
- Selection Marker:
- Neomycin
- Promoter:
- Enhanced CMV Promoter
- Expression:
- Transient
Catalog No. ABIN3293924
$4,272.84
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 61 to 62 Business Days
Synonyms and alternative names related to BRCA2
- BRCA2, DNA repair associated (BRCA2)
- Breast cancer 2, early onset homolog (Brca2)
- BRCA2, DNA repair associated (Brca2)
- breast cancer 2, early onset (brca2)
- breast cancer 2, early onset (LOC584780)
- BRCA2, DNA repair associated (brca2)
- breast cancer 2, early onset (Brca2)
- 30169
- AI256696
- AW045498
- BcDNA:SD25109
- brca2
- BRCA2
- BRCC2
- brcc2
- BROVCA2
- brovca2
- CG13583
- CG13584
- CG30169
- dmbrca2
- Dmel\\CG30169
- FACD
- facd
- FAD
- fad
- FAD1
- fad1
- FANCB
- fancb
- FANCD
- FANCD1
- fancd1
- Fancd1
- GLM3
- PNCA2
- RAB163
Gene-IDs for different species
Protein level used designations for BRCA2
- BRCA1/BRCA2-containing complex, subunit 2
- breast and ovarian cancer susceptibility gene, early onset
- breast cancer 2 tumor suppressor
- breast cancer type 2 susceptibility protein
- fanconi anemia group D1 protein
- truncated breast and ovarian cancer susceptibility protein 2
- breast cancer 2, early onset homolog
- CG30169-PA
- Brca2-PA
- breast cancer 2, mutation 1, University of Wisconsin-Madison
- breast cancer susceptibility protein 2
- breast cancer type 2 susceptibility protein homolog
- fanconi anemia group D1 protein homolog
- breast and ovarian cancer susceptibility protein 2
- breast cancer 2, early onset
- breast cancer type 2 susceptibility protein-like
Proteomics products related to BRCA2 Gene
Other products related to BRCA2 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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