BRCC3 (BRCA1/BRCA2-Containing Complex, Subunit 3, BRCC3)
Short Description: This gene encodes a subunit of the BRCA1-BRCA2-containing complex (BRCC), which is an E3 ubiquitin ligase. This complex plays a role in the DNA damage response, where it is responsible for the stable accumulation of BRCA1 at DNA break sites. The component encoded by this gene can specifically cleave Lys 63-linked polyubiquitin chains, and it regulates the abundance of these polyubiquitin chains in chromatin. The loss of this gene results in abnormal angiogenesis and is associated with syndromic moyamoya, a cerebrovascular angiopathy. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 5. [provided by RefSeq, Jun 2011].
More information related to gene BRCC3.
More information related to gene BRCC3.
Products related to BRCC3 Gene:
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OriGene tl506302
shRNA
RNAi
Lentiviral Vector
pGFP-C-shLenti
Chloramphenicol
U6 Promoter
GFP tag
Transient
1
- Type:
- shRNA
- Application:
- RNA Interference
- Gene:
- BRCA1/BRCA2-Containing Complex, Subunit 3 (BRCC3)
- Species:
- Mouse
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pGFP-C-shLenti
- Resistance Gene:
- Chloramphenicol
- Selection Marker:
- Puromycin
- Promoter:
- U6 Promoter
- Fusion Tag:
- GFP tag
- Expression:
- Transient, Stable
Catalog No. ABIN3518919
$1,002.87
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 16 to 17 Business Days
OriGene kn502250
gRNA + Cas9
GEEN
Mammalian Expression Vector
pCas-Guide
Ampicillin
U6 Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- gRNA + Cas9
- Application:
- Genome Editing with Engineered Nucleases
- Gene:
- BRCA1/BRCA2-Containing Complex, Subunit 3 (BRCC3)
- Species:
- Mouse
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCas-Guide
- Resistance Gene:
- Ampicillin
- Promoter:
- U6 Promoter, Enhanced CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN3248079
$1,640.43
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 21 to 22 Business Days
OriGene kn400727
gRNA + Cas9
GEEN
Mammalian Expression Vector
pCas-Guide
Ampicillin
U6 Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- gRNA + Cas9
- Application:
- Genome Editing with Engineered Nucleases
- Gene:
- BRCA1/BRCA2-Containing Complex, Subunit 3 (BRCC3)
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCas-Guide
- Resistance Gene:
- Ampicillin
- Promoter:
- U6 Promoter, Enhanced CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN3248078
$1,640.43
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 21 to 22 Business Days
Synonyms and alternative names related to BRCC3
- BRCA1/BRCA2-containing complex subunit 3 (BRCC3)
- DEP domain containing 1B (depdc1b)
- BRCA1/BRCA2-containing complex subunit 3 (brcc3)
- BRCA1/BRCA2-containing complex, subunit 3 (Brcc3)
- BRCA1/BRCA2-containing complex subunit 3 L homeolog (brcc3.L)
- BRCC3
- brcc3
- BRCC36
- brcc36
- C6.1A
- CXorf53
- xtp1
Gene-IDs for different species
Protein level used designations for BRCC3
- BRCA1/BRCA2-containing complex, subunit 3
- c6.1A
- BRCA1-A complex subunit BRCC36
- BRCA1/BRCA2-containing complex subunit 3
- BRCA1/BRCA2-containing complex subunit 36
- BRISC complex subunit BRCC36
- lys-63-specific deubiquitinase BRCC36
- 6.1A protein
Proteomics products related to BRCC3 Gene
Other products related to BRCC3 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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