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CD46 (CD46, CD46)

Short Description: The protein encoded by this gene is a type I membrane protein and is a regulatory part of the complement system. The encoded protein has cofactor activity for inactivation of complement components C3b and C4b by serum factor I, which protects the host cell from damage by complement. In addition, the encoded protein can act as a receptor for the Edmonston strain of measles virus, human herpesvirus-6, and type IV pili of pathogenic Neisseria. Finally, the protein encoded by this gene may be involved in the fusion of the spermatozoa with the oocyte during fertilization. Mutations at this locus have been associated with susceptibility to hemolytic uremic syndrome. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jun 2010].
More information related to gene CD46.

Products related to CD46 Gene:

111 results

OriGene tg512966 shRNA RNAi Retroviral Vector pGFP-V-RS Kanamycin U6 Promoter GFP tag Transient
Type:
shRNA
Application:
RNA Interference
Gene:
CD46 Molecule, Complement Regulatory Protein (CD46)
Species:
Mouse
Vector type:
Retroviral Vector
Vector backbone:
pGFP-V-RS
Resistance Gene:
Kanamycin
Selection Marker:
Puromycin
Promoter:
U6 Promoter
Fusion Tag:
GFP tag
Expression:
Transient, Stable
Catalog No. ABIN3694969
$707.85
Plus shipping costs $50.00
1 kit
Shipping to: United States
Will be delivered in 16 Business Days
OriGene tg710210 shRNA RNAi Retroviral Vector pGFP-V-RS Kanamycin U6 Promoter GFP tag Transient
Type:
shRNA
Application:
RNA Interference
Gene:
CD46 Molecule, Complement Regulatory Protein (CD46)
Species:
Rat
Vector type:
Retroviral Vector
Vector backbone:
pGFP-V-RS
Resistance Gene:
Kanamycin
Selection Marker:
Puromycin
Promoter:
U6 Promoter
Fusion Tag:
GFP tag
Expression:
Transient, Stable
Catalog No. ABIN3504418
$707.85
Plus shipping costs $50.00
1 kit
Shipping to: United States
Will be delivered in 16 Business Days
OriGene rc219489l1 ORF PExp Lentiviral Vector pLenti-C-Myc-DDK Chloramphenicol CMV Promoter Myc-DYKDDDDK Tag Transient
Type:
ORF
Application:
Protein Expression
Gene:
CD46 Molecule, Complement Regulatory Protein (CD46)
NCBI Accession:
NM_002389,NP_002380
Species:
Human
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-C-Myc-DDK
Resistance Gene:
Chloramphenicol
Promoter:
CMV Promoter
Fusion Tag:
Myc-DYKDDDDK Tag
Expression:
Transient
Catalog No. ABIN5449391
$749.43
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 8 to 10 Business Days
OriGene rc221012l1 ORF PExp Lentiviral Vector pLenti-C-Myc-DDK Chloramphenicol CMV Promoter Myc-DYKDDDDK Tag Transient
Type:
ORF
Application:
Protein Expression
Gene:
CD46 Molecule, Complement Regulatory Protein (CD46)
NCBI Accession:
NM_172351,NP_758861
Species:
Human
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-C-Myc-DDK
Resistance Gene:
Chloramphenicol
Promoter:
CMV Promoter
Fusion Tag:
Myc-DYKDDDDK Tag
Expression:
Transient
Catalog No. ABIN5449392
$749.43
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 8 to 10 Business Days
OriGene rc222383l2 ORF PExp Lentiviral Vector pLenti-C-mGFP Chloramphenicol CMV Promoter GFP tag Transient
Type:
ORF
Application:
Protein Expression
Gene:
CD46 Molecule, Complement Regulatory Protein (CD46)
NCBI Accession:
NM_172353,NP_758863
Species:
Human
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-C-mGFP
Resistance Gene:
Chloramphenicol
Promoter:
CMV Promoter
Fusion Tag:
GFP tag
Expression:
Transient
Catalog No. ABIN5449385
$749.43
Plus shipping costs $50.00
10 μg
Shipping to: United States
Will be delivered in 21 Business Days
OriGene rc219489l2 ORF PExp Lentiviral Vector pLenti-C-mGFP Chloramphenicol CMV Promoter GFP tag Transient
Type:
ORF
Application:
Protein Expression
Gene:
CD46 Molecule, Complement Regulatory Protein (CD46)
NCBI Accession:
NM_002389,NP_002380
Species:
Human
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-C-mGFP
Resistance Gene:
Chloramphenicol
Promoter:
CMV Promoter
Fusion Tag:
GFP tag
Expression:
Transient
Catalog No. ABIN5449378
$749.43
Plus shipping costs $50.00
10 μg
Shipping to: United States
Will be delivered in 21 Business Days
OriGene rc221012l2 ORF PExp Lentiviral Vector pLenti-C-mGFP Chloramphenicol CMV Promoter GFP tag Transient
Type:
ORF
Application:
Protein Expression
Gene:
CD46 Molecule, Complement Regulatory Protein (CD46)
NCBI Accession:
NM_172351,NP_758861
Species:
Human
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-C-mGFP
Resistance Gene:
Chloramphenicol
Promoter:
CMV Promoter
Fusion Tag:
GFP tag
Expression:
Transient
Catalog No. ABIN5449379
$749.43
Plus shipping costs $50.00
10 μg
Shipping to: United States
Will be delivered in 21 Business Days
OriGene rc222383l1 ORF PExp Lentiviral Vector pLenti-C-Myc-DDK Chloramphenicol CMV Promoter Myc-DYKDDDDK Tag Transient
Type:
ORF
Application:
Protein Expression
Gene:
CD46 Molecule, Complement Regulatory Protein (CD46)
NCBI Accession:
NM_172353,NP_758863
Species:
Human
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-C-Myc-DDK
Resistance Gene:
Chloramphenicol
Promoter:
CMV Promoter
Fusion Tag:
Myc-DYKDDDDK Tag
Expression:
Transient
Catalog No. ABIN5449398
$749.43
Plus shipping costs $50.00
10 μg
Shipping to: United States
Will be delivered in 21 Business Days
OriGene tr305510 shRNA RNAi Retroviral Vector pRS Ampicillin U6 Promoter unconjugated Transient
Type:
shRNA
Application:
RNA Interference
Gene:
CD46 Molecule, Complement Regulatory Protein (CD46)
Species:
Human
Vector type:
Retroviral Vector
Vector backbone:
pRS
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter
Expression:
Transient, Stable
Catalog No. ABIN3771082
$874.17
Plus shipping costs $50.00
1 kit
Shipping to: United States
Will be delivered in 16 Business Days
OriGene tr710210 shRNA RNAi Retroviral Vector pRS Ampicillin U6 Promoter unconjugated Transient
Type:
shRNA
Application:
RNA Interference
Gene:
CD46 Molecule, Complement Regulatory Protein (CD46)
Species:
Rat
Vector type:
Retroviral Vector
Vector backbone:
pRS
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter
Expression:
Transient, Stable
Catalog No. ABIN3435100
$874.17
Plus shipping costs $50.00
1 kit
Shipping to: United States
Will be delivered in 16 Business Days
  • Type
    • Plasmid
    • Primer
  • Supplier
    • OriGene
    • antibodies-online
    • GenScript
    • ProteoGenix
  • Reactivity
    • Human
    • Mouse
    • Rat
  • Cited in publications
  • Application
    • Protein Expression (PExp)
    • Genome Editing with Engineered Nucleases (GEEN)
    • Cloning (Clon)
    • RNA Interference (RNAi)
  • Conjugate
    • Un-conjugated
    • GFP tag
    • Myc-DYKDDDDK Tag
    • DYKDDDDK Tag
    • His tag
    • HA tag
    • His-GST
    • His-MBP
    • RFP tag
  • Vector Backbone
    • pCMV6-Entry
    • pCMV6-AC-GFP
    • pLenti-C-Myc-DDK
    • pLenti-C-mGFP
    • pcDNA3.1+C-(K)-DYK
    • pLenti-U6-sgRNA-PGK-Neo
    • pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
    • pCMV6-XL4
    • pGFP-C-shLenti
    • pGFP-V-RS
    • pORF
    • pPB-His-GST
    • pPB-His-MBP
    • pPB-N-His
    • pPM-C-HA
    • pPM-C-His
    • pRS
    • pCas-Guide
    • pCMV6-XL5
    • pDONR223
    • pRFP-C-RS
  • Vector
    • Mammalian Expression Vector
    • Lentiviral Vector
    • Bacterial Expression Vector
    • Retroviral Vector
    • Cloning Vector
    • Gateway Cloning Vector
  • Insert
    • ORF
    • cDNA
    • shRNA
    • gRNA + Cas9
    • gRNA
  • Type of Oligonucleotide
    • siRNA Oligo
  • Bacterial Resistance
    • Ampicillin
    • Kanamycin
    • Chloramphenicol
    • Spectinomycin
  • Expression Type
    • Transient
    • Stable
  • Selectable Marker
    • Neomycin
    • Puromycin
  • Promoter
    • CMV Promoter
    • U6 Promoter
    • Enhanced CMV Promoter
    • T7 Promoter
    • PGK Promoter
    • SFFV Promoter
  • Format
    • Lyophilized
    • Viral Particles
    • Liquid

Synonyms and alternative names related to CD46

  • CD46 molecule (CD46)
  • CD46 antigen, complement regulatory protein (Cd46)
  • CD46 molecule (Cd46)
  • CD46 molecule, complement regulatory protein (CD46)
  • membrane cofactor protein-like (LOC100341359)
  • membrane cofactor protein-like (LOC103789310)
  • AHUS2
  • CD46
  • MCP
  • Mcp
  • MIC10
  • TLX
  • TRA2.10

Gene-IDs for different species

Protein level used designations for CD46

  • CD46 antigen, complement regulatory protein
  • antigen identified by monoclonal antibody TRA-2-10
  • complement membrane cofactor protein
  • measles virus receptor
  • membrane cofactor protein
  • membrane cofactor protein (CD46, trophoblast-lymphocyte cross-reactive antigen)
  • trophoblast leucocyte common antigen
  • trophoblast leukocyte common antigen
  • trophoblast-lymphocyte cross-reactive antigen
  • brain microvascular membrane cofactor
  • membrane cofactor protein(GMP1-full)
  • CD46 molecule
  • Membrane cofactor protein
Other products related to CD46 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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