DLAT (Dihydrolipoyl Transacetylase, DLAT)
Short Description: This gene encodes component E2 of the multi-enzyme pyruvate dehydrogenase complex (PDC). PDC resides in the inner mitochondrial membrane and catalyzes the conversion of pyruvate to acetyl coenzyme A. The protein product of this gene, dihydrolipoamide acetyltransferase, accepts acetyl groups formed by the oxidative decarboxylation of pyruvate and transfers them to coenzyme A. Dihydrolipoamide acetyltransferase is the antigen for antimitochondrial antibodies. These autoantibodies are present in nearly 95% of patients with the autoimmune liver disease primary biliary cirrhosis (PBC). In PBC, activated T lymphocytes attack and destroy epithelial cells in the bile duct where this protein is abnormally distributed and overexpressed. PBC enventually leads to cirrhosis and liver failure. Mutations in this gene are also a cause of pyruvate dehydrogenase E2 deficiency which causes primary lactic acidosis in infancy and early childhood.[provided by RefSeq, Oct 2009].
More information related to gene DLAT.
More information related to gene DLAT.
Products related to DLAT Gene:
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56 results
OriGene tl507127
shRNA
RNAi
Lentiviral Vector
pGFP-C-shLenti
Chloramphenicol
U6 Promoter
GFP tag
Transient
1
- Type:
- shRNA
- Application:
- RNA Interference
- Gene:
- Dihydrolipoyl Transacetylase (DLAT)
- Species:
- Mouse
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pGFP-C-shLenti
- Resistance Gene:
- Chloramphenicol
- Selection Marker:
- Puromycin
- Promoter:
- U6 Promoter
- Fusion Tag:
- GFP tag
- Expression:
- Transient, Stable
Catalog No. ABIN3519744
$1,002.87
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 16 to 17 Business Days
OriGene tr507127
shRNA
RNAi
Retroviral Vector
pRS
Ampicillin
U6 Promoter
unconjugated
Transient
1
- Type:
- shRNA
- Application:
- RNA Interference
- Gene:
- Dihydrolipoyl Transacetylase (DLAT)
- Species:
- Mouse
- Vector type:
- Retroviral Vector
- Vector backbone:
- pRS
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Puromycin
- Promoter:
- U6 Promoter
- Expression:
- Transient, Stable
Catalog No. ABIN3539460
$874.17
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 16 to 17 Business Days
OriGene sr418587
RNAi
DLAT
Species: Mouse
HPLC purified
- Application:
- RNA Interference
- Gene:
- Dihydrolipoyl Transacetylase
- Species:
- Mouse
- Purification:
- HPLC purified
Catalog No. ABIN3266109
$512.82
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 16 to 17 Business Days
OriGene kn406640
gRNA + Cas9
GEEN
Mammalian Expression Vector
pCas-Guide
Ampicillin
U6 Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- gRNA + Cas9
- Application:
- Genome Editing with Engineered Nucleases
- Gene:
- Dihydrolipoyl Transacetylase (DLAT)
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCas-Guide
- Resistance Gene:
- Ampicillin
- Promoter:
- U6 Promoter, Enhanced CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN3253293
$1,640.43
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 21 to 22 Business Days
OriGene kn504604
gRNA + Cas9
GEEN
Mammalian Expression Vector
pCas-Guide
Ampicillin
U6 Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- gRNA + Cas9
- Application:
- Genome Editing with Engineered Nucleases
- Gene:
- Dihydrolipoyl Transacetylase (DLAT)
- Species:
- Mouse
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCas-Guide
- Resistance Gene:
- Ampicillin
- Promoter:
- U6 Promoter, Enhanced CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN3253294
$1,640.43
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 21 to 22 Business Days
OriGene sr512530
RNAi
DLAT
Species: Rat
HPLC purified
- Application:
- RNA Interference
- Gene:
- Dihydrolipoyl Transacetylase
- Species:
- Rat
- Purification:
- HPLC purified
Catalog No. ABIN3361288
$512.82
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 16 to 17 Business Days
OriGene tf711156
shRNA
RNAi
Retroviral Vector
pRFP-C-RS
Chloramphenicol
U6 Promoter
RFP tag
Transient
1
- Type:
- shRNA
- Application:
- RNA Interference
- Gene:
- Dihydrolipoyl Transacetylase (DLAT)
- Species:
- Rat
- Vector type:
- Retroviral Vector
- Vector backbone:
- pRFP-C-RS
- Resistance Gene:
- Chloramphenicol
- Selection Marker:
- Puromycin
- Promoter:
- U6 Promoter
- Fusion Tag:
- RFP tag
- Expression:
- Transient, Stable
Catalog No. ABIN3491432
$707.85
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 16 to 17 Business Days
OriGene rn212819
cDNA
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
Enhanced CMV Promoter
unconjugated
Transient
1
- Type:
- cDNA
- Application:
- Protein Expression
- Gene:
- Dihydrolipoyl Transacetylase (DLAT)
- NCBI Accession:
- NM_031025,NP_112287
- Species:
- Rat
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-Entry
- Resistance Gene:
- Kanamycin
- Selection Marker:
- Neomycin
- Promoter:
- Enhanced CMV Promoter
- Expression:
- Transient
Catalog No. ABIN3290375
$641.52
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 21 to 22 Business Days
OriGene sc100111
cDNA
PExp
Mammalian Expression Vector
pCMV6-XL4
Ampicillin
Enhanced CMV Promoter
unconjugated
Transient
1
- Type:
- cDNA
- Application:
- Protein Expression
- Gene:
- Dihydrolipoyl Transacetylase (DLAT)
- NCBI Accession:
- NM_001931,NP_001922
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-XL4
- Resistance Gene:
- Ampicillin
- Promoter:
- Enhanced CMV Promoter, T7 Promoter
- Expression:
- Transient
Catalog No. ABIN3377746
$894.96
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 4 to 9 Business Days
ORF
PExp
Mammalian Expression Vector
pcDNA3.1+C-(K)-DYK
Ampicillin
CMV Promoter
DYKDDDDK Tag
Transient
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Dihydrolipoyl Transacetylase (DLAT)
- NCBI Accession:
- NM_001931
- Gene ID:
- 1737 (Human, DLAT)
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pcDNA3.1+C-(K)-DYK
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Neomycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- DYKDDDDK Tag
- Expression:
- Transient, Stable
Catalog No. ABIN4919940
$379.00
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 4 to 7 Business Days
Synonyms and alternative names related to DLAT
- midline uncoordinated (muc)
- dihydrolipoamide S-acetyltransferase L homeolog (dlat.L)
- dihydrolipoamide S-acetyltransferase (DLAT)
- dihydrolipoamide S-acetyltransferase (Dlat)
- dihydrolipoamide S-acetyltransferase (E2 component of pyruvate dehydrogenase complex) (dlat)
- dihydrolipoamide S-acetyltransferase (E2 component of pyruvate dehydrogenase complex) (Dlat)
- 6332404G05Rik
- anon-WO0118547.121
- DLAT
- DLTA
- Dmel\\CG5261
- EP(2)0816
- EP816
- PDC-E2
- PDCE2
- wu:fc14f10
- wu:fc21f08
- wu:fc86g11
- wu:fj57d06
Gene-IDs for different species
Protein level used designations for DLAT
- CG5261-PA
- CG5261-PB
- CG5261-PC
- CG5261-PD
- CG5261-PE
- CG5261-PF
- Dihydrolipoyllysine-residue acetyltransferase
- dihydrolipoamide acetyltransferase
- dihydrolipoamide S-acetyltransferase (E2 component of pyruvate dehydrogenase complex)
- 70 kDa mitochondrial autoantigen of primary biliary cirrhosis
- E2 component of pyruvate dehydrogenase complex
- M2 antigen complex 70 kDa subunit
- PBC
- dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
- dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex mitochondrial
- dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial
- pyruvate dehydrogenase complex component E2
- dihydrolipoyllysine-residue acetyltransferase
- E2
- PDC-E2
- PDCE2
- fc86g11
- fj57d06
- no optokinetic nystagmus a
- no optokinetic response b
- noa
- nrb
Proteomics products related to DLAT Gene
Other products related to DLAT such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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