HLA-DRB5 (Major Histocompatibility Complex, Class II, DR beta 5, HLA-DRB5)
Short Description: HLA-DRB5 belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DRA) and a beta (DRB) chain, both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa and its gene contains 6 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail. Within the DR molecule the beta chain contains all the polymorphisms specifying the peptide binding specificities. Typing for these polymorphisms is routinely done for bone marrow and kidney transplantation. DRB1 is expressed at a level five times higher than its paralogues DRB3, DRB4 and DRB5. The presence of DRB5 is linked with allelic variants of DRB1, otherwise it is omitted. There are 4 related pseudogenes: DRB2, DRB6, DRB7, DRB8 and DRB9. [provided by RefSeq, Jul 2008].
More information related to gene HLA-DRB5.
More information related to gene HLA-DRB5.
Products related to HLA-DRB5 Gene:
Recommended next Filters:
14 results
ORF
Clon
Gateway Cloning Vector
pDONR223
Spectinomycin
unconjugated
Catalog No. ABIN5311983
$223.79
Plus shipping costs $50.00
2 μg
Shipping to:
United States
Delivery in 15 to 17 Business Days
ORF
PExp
Mammalian Expression Vector
pcDNA3.1+C-(K)-DYK
Ampicillin
CMV Promoter
DYKDDDDK Tag
Transient
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Major Histocompatibility Complex, Class II, DR beta 5 (HLA-DRB5)
- NCBI Accession:
- NM_002125
- Gene ID:
- 3127 (Human, HLA-DRB5)
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pcDNA3.1+C-(K)-DYK
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Neomycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- DYKDDDDK Tag
- Expression:
- Transient, Stable
Catalog No. ABIN4938765
$309.00
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 4 to 6 Business Days
OriGene rc203646
ORF
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
CMV Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Major Histocompatibility Complex, Class II, DR beta 5 (HLA-DRB5)
- NCBI Accession:
- NM_002125,NP_002116
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-Entry
- Resistance Gene:
- Kanamycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN5488034
$297.00
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 8 to 10 Business Days
OriGene rg203646
ORF
PExp
Mammalian Expression Vector
pCMV6-AC-GFP
Ampicillin
CMV Promoter
GFP tag
Stable
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Major Histocompatibility Complex, Class II, DR beta 5 (HLA-DRB5)
- NCBI Accession:
- NM_002125,NP_002116
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-AC-GFP
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Neomycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- GFP tag
- Expression:
- Stable, Transient
Catalog No. ABIN5488033
$484.11
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Will be delivered in 21 Business Days
Synonyms and alternative names related to HLA-DRB5
- major histocompatibility complex, class II, DR beta 5 (HLA-DRB5)
- HLA-DRB
Gene-IDs for different species
Protein level used designations for HLA-DRB5
- DR beta-5
- DR-9
- DR2-beta-2
- DR9
- HLA class II histocompatibility antigen, DR beta 5 chain
- HLA class II histocompatibility antigen, DR-5 beta chain
- HLA class II histocompatibility antigen, DRB1-9 beta chain
- MHC HLA-DR-beta cell surface glycoprotein
- MHC HLA-DR-beta chain
- MHC class II HLA beta chain
- MHC class II antigen DRB1*9
- MHC class II antigen DRB5
- dw2
- human leucocyte antigen DRB5
- leukocyte antigen class II
Proteomics products related to HLA-DRB5 Gene
Other products related to HLA-DRB5 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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