HMGCR (3-Hydroxy-3-Methylglutaryl-CoA Reductase, HMGCR)
Short Description: HMG-CoA reductase is the rate-limiting enzyme for cholesterol synthesis and is regulated via a negative feedback mechanism mediated by sterols and non-sterol metabolites derived from mevalonate, the product of the reaction catalyzed by reductase. Normally in mammalian cells this enzyme is suppressed by cholesterol derived from the internalization and degradation of low density lipoprotein (LDL) via the LDL receptor. Competitive inhibitors of the reductase induce the expression of LDL receptors in the liver, which in turn increases the catabolism of plasma LDL and lowers the plasma concentration of cholesterol, an important determinant of atherosclerosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008].
More information related to gene HMGCR.
More information related to gene HMGCR.
Products related to HMGCR Gene:
Recommended next Filters:
57 results
ORF
PExp
Mammalian Expression Vector
pcDNA3.1+C-(K)-DYK
Ampicillin
CMV Promoter
DYKDDDDK Tag
Transient
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- 3-Hydroxy-3-Methylglutaryl-CoA Reductase (HMGCR)
- NCBI Accession:
- NM_001130996
- Gene ID:
- 3156 (Human, HMGCR)
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pcDNA3.1+C-(K)-DYK
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Neomycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- DYKDDDDK Tag
- Expression:
- Transient, Stable
Catalog No. ABIN4943650
$679.00
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Will be delivered in 31 Business Days
ORF
PExp
Mammalian Expression Vector
pcDNA3.1+C-(K)-DYK
Ampicillin
CMV Promoter
DYKDDDDK Tag
Transient
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- 3-Hydroxy-3-Methylglutaryl-CoA Reductase (HMGCR)
- NCBI Accession:
- NM_000859
- Gene ID:
- 3156 (Human, HMGCR)
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pcDNA3.1+C-(K)-DYK
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Neomycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- DYKDDDDK Tag
- Expression:
- Transient, Stable
Catalog No. ABIN4938752
$679.00
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 4 to 6 Business Days
OriGene tg312393
shRNA
RNAi
Retroviral Vector
pGFP-V-RS
Kanamycin
U6 Promoter
GFP tag
Transient
1
- Type:
- shRNA
- Application:
- RNA Interference
- Gene:
- 3-Hydroxy-3-Methylglutaryl-CoA Reductase (HMGCR)
- Species:
- Human
- Vector type:
- Retroviral Vector
- Vector backbone:
- pGFP-V-RS
- Resistance Gene:
- Kanamycin
- Selection Marker:
- Puromycin
- Promoter:
- U6 Promoter
- Fusion Tag:
- GFP tag
- Expression:
- Transient, Stable
Catalog No. ABIN3737236
$707.85
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Will be delivered in 16 Business Days
OriGene tf511652
shRNA
RNAi
Retroviral Vector
pRFP-C-RS
Chloramphenicol
U6 Promoter
RFP tag
Transient
1
- Type:
- shRNA
- Application:
- RNA Interference
- Gene:
- 3-Hydroxy-3-Methylglutaryl-CoA Reductase (HMGCR)
- Species:
- Mouse
- Vector type:
- Retroviral Vector
- Vector backbone:
- pRFP-C-RS
- Resistance Gene:
- Chloramphenicol
- Selection Marker:
- Puromycin
- Promoter:
- U6 Promoter
- Fusion Tag:
- RFP tag
- Expression:
- Transient, Stable
Catalog No. ABIN3673959
$707.85
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Will be delivered in 16 Business Days
OriGene tg511652
shRNA
RNAi
Retroviral Vector
pGFP-V-RS
Kanamycin
U6 Promoter
GFP tag
Transient
1
- Type:
- shRNA
- Application:
- RNA Interference
- Gene:
- 3-Hydroxy-3-Methylglutaryl-CoA Reductase (HMGCR)
- Species:
- Mouse
- Vector type:
- Retroviral Vector
- Vector backbone:
- pGFP-V-RS
- Resistance Gene:
- Kanamycin
- Selection Marker:
- Puromycin
- Promoter:
- U6 Promoter
- Fusion Tag:
- GFP tag
- Expression:
- Transient, Stable
Catalog No. ABIN3693657
$707.85
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Will be delivered in 16 Business Days
OriGene tf709727
shRNA
RNAi
Retroviral Vector
pRFP-C-RS
Chloramphenicol
U6 Promoter
RFP tag
Transient
1
- Type:
- shRNA
- Application:
- RNA Interference
- Gene:
- 3-Hydroxy-3-Methylglutaryl-CoA Reductase (HMGCR)
- Species:
- Rat
- Vector type:
- Retroviral Vector
- Vector backbone:
- pRFP-C-RS
- Resistance Gene:
- Chloramphenicol
- Selection Marker:
- Puromycin
- Promoter:
- U6 Promoter
- Fusion Tag:
- RFP tag
- Expression:
- Transient, Stable
Catalog No. ABIN3490006
$707.85
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Will be delivered in 16 Business Days
OriGene tg709727
shRNA
RNAi
Retroviral Vector
pGFP-V-RS
Kanamycin
U6 Promoter
GFP tag
Transient
1
- Type:
- shRNA
- Application:
- RNA Interference
- Gene:
- 3-Hydroxy-3-Methylglutaryl-CoA Reductase (HMGCR)
- Species:
- Rat
- Vector type:
- Retroviral Vector
- Vector backbone:
- pGFP-V-RS
- Resistance Gene:
- Kanamycin
- Selection Marker:
- Puromycin
- Promoter:
- U6 Promoter
- Fusion Tag:
- GFP tag
- Expression:
- Transient, Stable
Catalog No. ABIN3503937
$707.85
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Will be delivered in 16 Business Days
OriGene tr312393
shRNA
RNAi
Retroviral Vector
pRS
Ampicillin
U6 Promoter
unconjugated
Transient
1
- Type:
- shRNA
- Application:
- RNA Interference
- Gene:
- 3-Hydroxy-3-Methylglutaryl-CoA Reductase (HMGCR)
- Species:
- Human
- Vector type:
- Retroviral Vector
- Vector backbone:
- pRS
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Puromycin
- Promoter:
- U6 Promoter
- Expression:
- Transient, Stable
Catalog No. ABIN3654334
$874.17
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Will be delivered in 16 Business Days
OriGene tr709727
shRNA
RNAi
Retroviral Vector
pRS
Ampicillin
U6 Promoter
unconjugated
Transient
1
- Type:
- shRNA
- Application:
- RNA Interference
- Gene:
- 3-Hydroxy-3-Methylglutaryl-CoA Reductase (HMGCR)
- Species:
- Rat
- Vector type:
- Retroviral Vector
- Vector backbone:
- pRS
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Puromycin
- Promoter:
- U6 Promoter
- Expression:
- Transient, Stable
Catalog No. ABIN3443124
$874.17
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Will be delivered in 16 Business Days
OriGene tr511652
shRNA
RNAi
Retroviral Vector
pRS
Ampicillin
U6 Promoter
unconjugated
Transient
1
- Type:
- shRNA
- Application:
- RNA Interference
- Gene:
- 3-Hydroxy-3-Methylglutaryl-CoA Reductase (HMGCR)
- Species:
- Mouse
- Vector type:
- Retroviral Vector
- Vector backbone:
- pRS
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Puromycin
- Promoter:
- U6 Promoter
- Expression:
- Transient, Stable
Catalog No. ABIN3543970
$874.17
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Will be delivered in 16 Business Days
Synonyms and alternative names related to HMGCR
- 3-hydroxy-3-methylglutaryl-CoA reductase (HMGCR)
- 3-hydroxy-3-methylglutaryl-CoA reductase L homeolog (hmgcr.L)
- 3-hydroxy-3-methylglutaryl-Coenzyme A reductase (Hmgcr)
- 3-hydroxy-3-methylglutaryl-CoA reductase (Hmgcr)
- HMG Coenzyme A reductase (Hmgcr)
- 3-hydroxy-3-methylglutaryl-CoA reductase b (hmgcrb)
- 3H3M
- BcDNA:LD15354
- bro1
- bs32f05.y1
- CG10367
- Clb
- clb
- Dmel\\CG10367
- DmHMG-CoAr
- Hmg
- hmg-coa-r
- HMG-CoAR
- HmG-CoAR
- hmgc
- HMGCoAR
- HMGCoAr
- HMGCoARr
- HMGCR
- hmgcr
- hmgcr2
- HMGCR_Dm
- HMGR
- hmgrc
- im:6912716
- l(3)01152
- l(3)04684
- LDLCQ3
- Red
- zgc:110746
Gene-IDs for different species
Protein level used designations for HMGCR
- 3-hydroxy-3-methylglutaryl-Coenzyme A reductase
- 3-hydroxy-3-methylglutaryl coenzyme A reductase/HMG-CoA reductase
- 3-hydroxy-3-methylglutaryl-coenzyme A reductase
- 3-hydroxy-3-methylglutaryl CoA reductase (NADPH)
- HMG-CoA reductase
- hydroxymethylglutaryl-CoA reductase
- 3-hydroxy-3-methylglutaryl CoA reductase
- 3-hydroxy-3-methylglutaryl-CoA reductase
- 3-Hydroxy-3-Methylglutaryl CoA reductase
- 3-hydroxy-3-methylglutaryl coenzyme A reductase
- CG10367-PA
- HMG coenzyme A reductase
- HMGCo-A reductase
- HMGCoA reductase
- Hmg-CoA-reductase
- Hmgcr-PA
- columbus
- lethal (3) 04684
- 3-alpha-hydroxy-3-methylglutaryl-CoA reductase
- 3-hydroxy-3-methylglutaryl-CoA reductase b
- 3-hydroxy-3-methylglutaryl-Coenzyme A reductase b
- hmgcr1b
- hmgrb
Proteomics products related to HMGCR Gene
Other products related to HMGCR such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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