HMGCR (3-Hydroxy-3-Methylglutaryl-CoA Reductase, HMGCR)
Short Description: HMG-CoA reductase is the rate-limiting enzyme for cholesterol synthesis and is regulated via a negative feedback mechanism mediated by sterols and non-sterol metabolites derived from mevalonate, the product of the reaction catalyzed by reductase. Normally in mammalian cells this enzyme is suppressed by cholesterol derived from the internalization and degradation of low density lipoprotein (LDL) via the LDL receptor. Competitive inhibitors of the reductase induce the expression of LDL receptors in the liver, which in turn increases the catabolism of plasma LDL and lowers the plasma concentration of cholesterol, an important determinant of atherosclerosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008].
More information related to gene HMGCR.
More information related to gene HMGCR.
Products related to HMGCR Gene:
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57 results
OriGene tl312393
shRNA
RNAi
Lentiviral Vector
pGFP-C-shLenti
Chloramphenicol
U6 Promoter
GFP tag
Transient
1
- Type:
- shRNA
- Application:
- RNA Interference
- Gene:
- 3-Hydroxy-3-Methylglutaryl-CoA Reductase (HMGCR)
- Species:
- Human
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pGFP-C-shLenti
- Resistance Gene:
- Chloramphenicol
- Selection Marker:
- Puromycin
- Promoter:
- U6 Promoter
- Fusion Tag:
- GFP tag
- Expression:
- Transient, Stable
Catalog No. ABIN3757574
$1,002.87
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Will be delivered in 16 Business Days
OriGene tl709727
shRNA
RNAi
Lentiviral Vector
pGFP-C-shLenti
Chloramphenicol
U6 Promoter
GFP tag
Transient
1
- Type:
- shRNA
- Application:
- RNA Interference
- Gene:
- 3-Hydroxy-3-Methylglutaryl-CoA Reductase (HMGCR)
- Species:
- Rat
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pGFP-C-shLenti
- Resistance Gene:
- Chloramphenicol
- Selection Marker:
- Puromycin
- Promoter:
- U6 Promoter
- Fusion Tag:
- GFP tag
- Expression:
- Transient, Stable
Catalog No. ABIN3447010
$1,002.87
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Will be delivered in 16 Business Days
OriGene tl511652
shRNA
RNAi
Lentiviral Vector
pGFP-C-shLenti
Chloramphenicol
U6 Promoter
GFP tag
Transient
1
- Type:
- shRNA
- Application:
- RNA Interference
- Gene:
- 3-Hydroxy-3-Methylglutaryl-CoA Reductase (HMGCR)
- Species:
- Mouse
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pGFP-C-shLenti
- Resistance Gene:
- Chloramphenicol
- Selection Marker:
- Puromycin
- Promoter:
- U6 Promoter
- Fusion Tag:
- GFP tag
- Expression:
- Transient, Stable
Catalog No. ABIN3524254
$1,002.87
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Will be delivered in 16 Business Days
OriGene rc226201
ORF
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
CMV Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- 3-Hydroxy-3-Methylglutaryl-CoA Reductase (HMGCR)
- NCBI Accession:
- NM_001130996,NP_001124468
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-Entry
- Resistance Gene:
- Kanamycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN5443984
$1,135.53
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Will be delivered in 21 Business Days
OriGene sc325352
cDNA
PExp
Mammalian Expression Vector
pCMV6-XL5
Ampicillin
Enhanced CMV Promoter
unconjugated
Transient
1
- Type:
- cDNA
- Application:
- Protein Expression
- Gene:
- 3-Hydroxy-3-Methylglutaryl-CoA Reductase (HMGCR)
- NCBI Accession:
- NM_001130996,NP_001124468
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-XL5
- Resistance Gene:
- Ampicillin
- Promoter:
- Enhanced CMV Promoter, T7 Promoter
- Expression:
- Transient
Catalog No. ABIN3390107
$1,136.52
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 4 to 8 Business Days
OriGene rn215489
cDNA
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
Enhanced CMV Promoter
unconjugated
Transient
1
- Type:
- cDNA
- Application:
- Protein Expression
- Gene:
- 3-Hydroxy-3-Methylglutaryl-CoA Reductase (HMGCR)
- NCBI Accession:
- NM_013134,NP_037266
- Species:
- Rat
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-Entry
- Resistance Gene:
- Kanamycin
- Selection Marker:
- Neomycin
- Promoter:
- Enhanced CMV Promoter
- Expression:
- Transient
Catalog No. ABIN3325265
$1,206.81
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Will be delivered in 31 Business Days
OriGene rc213184
ORF
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
CMV Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- 3-Hydroxy-3-Methylglutaryl-CoA Reductase (HMGCR)
- NCBI Accession:
- NM_000859,NP_000850
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-Entry
- Resistance Gene:
- Kanamycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN5443983
$1,206.81
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 8 to 10 Business Days
OriGene sc110921
cDNA
PExp
Mammalian Expression Vector
pCMV6-XL5
Ampicillin
Enhanced CMV Promoter
unconjugated
Transient
1
- Type:
- cDNA
- Application:
- Protein Expression
- Gene:
- 3-Hydroxy-3-Methylglutaryl-CoA Reductase (HMGCR)
- NCBI Accession:
- NM_000859,NP_000850
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-XL5
- Resistance Gene:
- Ampicillin
- Promoter:
- Enhanced CMV Promoter, T7 Promoter
- Expression:
- Transient
Catalog No. ABIN3384458
$1,208.79
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 4 to 8 Business Days
OriGene rr215489
ORF
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
CMV Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- 3-Hydroxy-3-Methylglutaryl-CoA Reductase (HMGCR)
- NCBI Accession:
- NM_013134,NP_037266
- Species:
- Rat
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-Entry
- Resistance Gene:
- Kanamycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN5443985
$1,286.01
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Will be delivered in 31 Business Days
OriGene rg226201
ORF
PExp
Mammalian Expression Vector
pCMV6-AC-GFP
Ampicillin
CMV Promoter
GFP tag
Stable
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- 3-Hydroxy-3-Methylglutaryl-CoA Reductase (HMGCR)
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-AC-GFP
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Neomycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- GFP tag
- Expression:
- Stable, Transient
Catalog No. ABIN5443982
$1,333.53
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 8 to 10 Business Days
Synonyms and alternative names related to HMGCR
- 3-hydroxy-3-methylglutaryl-CoA reductase (HMGCR)
- 3-hydroxy-3-methylglutaryl-CoA reductase L homeolog (hmgcr.L)
- 3-hydroxy-3-methylglutaryl-Coenzyme A reductase (Hmgcr)
- 3-hydroxy-3-methylglutaryl-CoA reductase (Hmgcr)
- HMG Coenzyme A reductase (Hmgcr)
- 3-hydroxy-3-methylglutaryl-CoA reductase b (hmgcrb)
- 3H3M
- BcDNA:LD15354
- bro1
- bs32f05.y1
- CG10367
- Clb
- clb
- Dmel\\CG10367
- DmHMG-CoAr
- Hmg
- hmg-coa-r
- HMG-CoAR
- HmG-CoAR
- hmgc
- HMGCoAR
- HMGCoAr
- HMGCoARr
- HMGCR
- hmgcr
- hmgcr2
- HMGCR_Dm
- HMGR
- hmgrc
- im:6912716
- l(3)01152
- l(3)04684
- LDLCQ3
- Red
- zgc:110746
Gene-IDs for different species
Protein level used designations for HMGCR
- 3-hydroxy-3-methylglutaryl-Coenzyme A reductase
- 3-hydroxy-3-methylglutaryl coenzyme A reductase/HMG-CoA reductase
- 3-hydroxy-3-methylglutaryl-coenzyme A reductase
- 3-hydroxy-3-methylglutaryl CoA reductase (NADPH)
- HMG-CoA reductase
- hydroxymethylglutaryl-CoA reductase
- 3-hydroxy-3-methylglutaryl CoA reductase
- 3-hydroxy-3-methylglutaryl-CoA reductase
- 3-Hydroxy-3-Methylglutaryl CoA reductase
- 3-hydroxy-3-methylglutaryl coenzyme A reductase
- CG10367-PA
- HMG coenzyme A reductase
- HMGCo-A reductase
- HMGCoA reductase
- Hmg-CoA-reductase
- Hmgcr-PA
- columbus
- lethal (3) 04684
- 3-alpha-hydroxy-3-methylglutaryl-CoA reductase
- 3-hydroxy-3-methylglutaryl-CoA reductase b
- 3-hydroxy-3-methylglutaryl-Coenzyme A reductase b
- hmgcr1b
- hmgrb
Proteomics products related to HMGCR Gene
Other products related to HMGCR such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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