HMGCR (3-Hydroxy-3-Methylglutaryl-CoA Reductase, HMGCR)
Short Description: HMG-CoA reductase is the rate-limiting enzyme for cholesterol synthesis and is regulated via a negative feedback mechanism mediated by sterols and non-sterol metabolites derived from mevalonate, the product of the reaction catalyzed by reductase. Normally in mammalian cells this enzyme is suppressed by cholesterol derived from the internalization and degradation of low density lipoprotein (LDL) via the LDL receptor. Competitive inhibitors of the reductase induce the expression of LDL receptors in the liver, which in turn increases the catabolism of plasma LDL and lowers the plasma concentration of cholesterol, an important determinant of atherosclerosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008].
More information related to gene HMGCR.
More information related to gene HMGCR.
Products related to HMGCR Gene:
Recommended next Filters:
57 results
OriGene rg213184
ORF
PExp
Mammalian Expression Vector
pCMV6-AC-GFP
Ampicillin
CMV Promoter
GFP tag
Stable
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- 3-Hydroxy-3-Methylglutaryl-CoA Reductase (HMGCR)
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-AC-GFP
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Neomycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- GFP tag
- Expression:
- Stable, Transient
Catalog No. ABIN5443981
$1,404.81
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 8 to 10 Business Days
OriGene rc226201l2
ORF
PExp
Lentiviral Vector
pLenti-C-mGFP
Chloramphenicol
CMV Promoter
GFP tag
Transient
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- 3-Hydroxy-3-Methylglutaryl-CoA Reductase (HMGCR)
- NCBI Accession:
- NM_001130996,NP_001124468
- Species:
- Human
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-C-mGFP
- Resistance Gene:
- Chloramphenicol
- Promoter:
- CMV Promoter
- Fusion Tag:
- GFP tag
- Expression:
- Transient
Catalog No. ABIN5443987
$1,432.53
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 8 to 10 Business Days
OriGene rc226201l1
ORF
PExp
Lentiviral Vector
pLenti-C-Myc-DDK
Chloramphenicol
CMV Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- 3-Hydroxy-3-Methylglutaryl-CoA Reductase (HMGCR)
- NCBI Accession:
- NM_001130996,NP_001124468
- Species:
- Human
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-C-Myc-DDK
- Resistance Gene:
- Chloramphenicol
- Promoter:
- CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN5443990
$1,432.53
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 6 to 8 Business Days
OriGene rc213184l2
ORF
PExp
Lentiviral Vector
pLenti-C-mGFP
Chloramphenicol
CMV Promoter
GFP tag
Transient
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- 3-Hydroxy-3-Methylglutaryl-CoA Reductase (HMGCR)
- NCBI Accession:
- NM_000859,NP_000850
- Species:
- Human
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-C-mGFP
- Resistance Gene:
- Chloramphenicol
- Promoter:
- CMV Promoter
- Fusion Tag:
- GFP tag
- Expression:
- Transient
Catalog No. ABIN5443986
$1,503.81
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 6 to 8 Business Days
OriGene rc213184l1
ORF
PExp
Lentiviral Vector
pLenti-C-Myc-DDK
Chloramphenicol
CMV Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- 3-Hydroxy-3-Methylglutaryl-CoA Reductase (HMGCR)
- NCBI Accession:
- NM_000859,NP_000850
- Species:
- Human
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-C-Myc-DDK
- Resistance Gene:
- Chloramphenicol
- Promoter:
- CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN5443989
$1,503.81
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 6 to 8 Business Days
OriGene kn507823
gRNA + Cas9
GEEN
Mammalian Expression Vector
pCas-Guide
Ampicillin
U6 Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- gRNA + Cas9
- Application:
- Genome Editing with Engineered Nucleases
- Gene:
- 3-Hydroxy-3-Methylglutaryl-CoA Reductase (HMGCR)
- Species:
- Mouse
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCas-Guide
- Resistance Gene:
- Ampicillin
- Promoter:
- U6 Promoter, Enhanced CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN3238157
$1,640.43
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Will be delivered in 21 Business Days
OriGene kn213184
gRNA + Cas9
GEEN
Mammalian Expression Vector
pCas-Guide
Ampicillin
U6 Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- gRNA + Cas9
- Application:
- Genome Editing with Engineered Nucleases
- Gene:
- 3-Hydroxy-3-Methylglutaryl-CoA Reductase (HMGCR)
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCas-Guide
- Resistance Gene:
- Ampicillin
- Promoter:
- U6 Promoter, Enhanced CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN3238156
$1,640.43
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Will be delivered in 21 Business Days
Synonyms and alternative names related to HMGCR
- 3-hydroxy-3-methylglutaryl-CoA reductase (HMGCR)
- 3-hydroxy-3-methylglutaryl-CoA reductase L homeolog (hmgcr.L)
- 3-hydroxy-3-methylglutaryl-Coenzyme A reductase (Hmgcr)
- 3-hydroxy-3-methylglutaryl-CoA reductase (Hmgcr)
- HMG Coenzyme A reductase (Hmgcr)
- 3-hydroxy-3-methylglutaryl-CoA reductase b (hmgcrb)
- 3H3M
- BcDNA:LD15354
- bro1
- bs32f05.y1
- CG10367
- Clb
- clb
- Dmel\\CG10367
- DmHMG-CoAr
- Hmg
- hmg-coa-r
- HMG-CoAR
- HmG-CoAR
- hmgc
- HMGCoAR
- HMGCoAr
- HMGCoARr
- HMGCR
- hmgcr
- hmgcr2
- HMGCR_Dm
- HMGR
- hmgrc
- im:6912716
- l(3)01152
- l(3)04684
- LDLCQ3
- Red
- zgc:110746
Gene-IDs for different species
Protein level used designations for HMGCR
- 3-hydroxy-3-methylglutaryl-Coenzyme A reductase
- 3-hydroxy-3-methylglutaryl coenzyme A reductase/HMG-CoA reductase
- 3-hydroxy-3-methylglutaryl-coenzyme A reductase
- 3-hydroxy-3-methylglutaryl CoA reductase (NADPH)
- HMG-CoA reductase
- hydroxymethylglutaryl-CoA reductase
- 3-hydroxy-3-methylglutaryl CoA reductase
- 3-hydroxy-3-methylglutaryl-CoA reductase
- 3-Hydroxy-3-Methylglutaryl CoA reductase
- 3-hydroxy-3-methylglutaryl coenzyme A reductase
- CG10367-PA
- HMG coenzyme A reductase
- HMGCo-A reductase
- HMGCoA reductase
- Hmg-CoA-reductase
- Hmgcr-PA
- columbus
- lethal (3) 04684
- 3-alpha-hydroxy-3-methylglutaryl-CoA reductase
- 3-hydroxy-3-methylglutaryl-CoA reductase b
- 3-hydroxy-3-methylglutaryl-Coenzyme A reductase b
- hmgcr1b
- hmgrb
Proteomics products related to HMGCR Gene
Other products related to HMGCR such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
You are here:
