HSPG2 (Heparan Sulfate Proteoglycan 2, HSPG2)
Short Description: This gene encodes the perlecan protein, which consists of a core protein to which three long chains of glycosaminoglycans (heparan sulfate or chondroitin sulfate) are attached. The perlecan protein is a large multidomain proteoglycan that binds to and cross-links many extracellular matrix components and cell-surface molecules. It has been shown that this protein interacts with laminin, prolargin, collagen type IV, FGFBP1, FBLN2, FGF7 and Transthyretin, etc. and plays essential roles in multiple biological activities. Perlecan is a key component of the vascular extracellular matrix, where it helps to maintain the endothelial barrier function. It is a potent inhibitor of smooth muscle cell proliferation and is thus thought to help maintain vascular homeostasis. It can also promote growth factor (e.g., FGF2) activity and thus stimulate endothelial growth and re-generation. It is a major component of basement membranes, where it is involved in the stabilization of other molecules as well as being involved with glomerular permeability to macromolecules and cell adhesion. Mutations in this gene cause Schwartz-Jampel syndrome type 1, Silverman-Handmaker type of dyssegmental dysplasia, and Tardive dyskinesia.[provided by RefSeq, Mar 2010].
More information related to gene HSPG2.
More information related to gene HSPG2.
Products related to HSPG2 Gene:
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33 results
OriGene sc308976
cDNA
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
Enhanced CMV Promoter
unconjugated
Transient
1
- Type:
- cDNA
- Application:
- Protein Expression
- Gene:
- Heparan Sulfate Proteoglycan 2 (HSPG2)
- NCBI Accession:
- NM_005529,NP_005520
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-Entry
- Resistance Gene:
- Kanamycin
- Selection Marker:
- Neomycin
- Promoter:
- Enhanced CMV Promoter
- Expression:
- Transient
Catalog No. ABIN3322576
$3,802.59
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 21 to 22 Business Days
OriGene rg223950
ORF
PExp
Mammalian Expression Vector
pCMV6-AC-GFP
Ampicillin
CMV Promoter
GFP tag
Stable
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Heparan Sulfate Proteoglycan 2 (HSPG2)
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-AC-GFP
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Neomycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- GFP tag
- Expression:
- Stable, Transient
Catalog No. ABIN5372998
$3,853.08
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 8 to 11 Business Days
OriGene rc223950l1v
ORF
PExp
Lentiviral Vector
pLenti-C-Myc-DDK
Chloramphenicol
CMV Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Heparan Sulfate Proteoglycan 2 (HSPG2)
- Species:
- Human
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-C-Myc-DDK
- Resistance Gene:
- Chloramphenicol
- Promoter:
- CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN6426006
$4,001.58
Plus shipping costs $50.00, if applicable $20.00 dry ice
200 μL
Shipping to:
United States
Delivery in 21 to 27 Business Days
Synonyms and alternative names related to HSPG2
- heparan sulfate proteoglycan 2 (HSPG2)
- heparan sulfate proteoglycan 2 (hspg2)
- perlecan (heparan sulfate proteoglycan 2) (Hspg2)
- heparan sulfate proteoglycan 2 (Hspg2)
- AI852380
- HSPG
- HSPG2
- Pcn
- per
- Per
- PLC
- Plc
- PRCAN
- SJA
- SJS
- SJS1
Gene-IDs for different species
Protein level used designations for HSPG2
- basement membrane-specific heparan sulfate proteoglycan core protein
- endorepellin (domain V region)
- perlecan proteoglycan
- heparan sulfate proteoglycan 2
- perlecan
- basement membrane-specific heparan sulfate proteoglycan core protein-like
- HSPG
- perlecan (heparan sulfate proteoglycan 2)
Proteomics products related to HSPG2 Gene
Other products related to HSPG2 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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