Short Description: Nucleocytoplasmic transport, a signal- and energy-dependent process, takes place through nuclear pore complexes embedded in the nuclear envelope. The import of proteins containing a nuclear localization signal (NLS) requires the NLS import receptor, a heterodimer of importin alpha and beta subunits also known as karyopherins. Importin alpha binds the NLS-containing cargo in the cytoplasm and importin beta docks the complex at the cytoplasmic side of the nuclear pore complex. In the presence of nucleoside triphosphates and the small GTP binding protein Ran, the complex moves into the nuclear pore complex and the importin subunits dissociate. Importin alpha enters the nucleoplasm with its passenger protein and importin beta remains at the pore. Interactions between importin beta and the FG repeats of nucleoporins are essential in translocation through the pore complex. The protein encoded by this gene is a member of the importin beta family. [provided by RefSeq, Jul 2008]. More information related to gene Importin 5.
Synonyms and alternative names related to Importin 5
importin 5 (IPO5)
importin 5 (Ipo5)
1110011C18Rik
5730478E03Rik
AA409333
C76941
IMB3
imp5
IPO5
KPNB3
Kpnb3
Pse1
RANBP5
Ranbp5
Gene-IDs for different species
Protein level used designations for Importin 5
importin 5
RAN binding protein 5
Ran_GTP binding protein 5
importin beta-3 subunit
importin subunit beta-3
importin-5
karyopherin (importin) beta 3
karyopherin beta-3
ran-binding protein 5
imp5
Proteomics products related to Importin 5 Gene
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