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JAK1 (Janus Kinase 1, JAK1)
Short Description: Janus kinase 1 (JAK1), is a member of a new class of protein-tyrosine kinases (PTK) characterized by the presence of a second phosphotransferase-related domain immediately N-terminal to the PTK domain. The second phosphotransferase domain bears all the hallmarks of a protein kinase, although its structure differs significantly from that of the PTK and threonine/serine kinase family members. JAK1 is a large, widely expressed membrane-associated phosphoprotein. JAK1 is involved in the interferon-alpha/beta and -gamma signal transduction pathways. The reciprocal interdependence between JAK1 and TYK2 activities in the interferon-alpha pathway, and between JAK1 and JAK2 in the interferon-gamma pathway, may reflect a requirement for these kinases in the correct assembly of interferon receptor complexes. These kinases couple cytokine ligand binding to tyrosine phosphorylation of various known signaling proteins and of a unique family of transcription factors termed the signal transducers and activators of transcription, or STATs. [provided by RefSeq, Jul 2008].
More information related to gene JAK1.
Products related to JAK1 Gene:
Recommended next Filters:
OriGene rc213878l2v
ORF
PExp
Lentiviral Vector
pLenti-C-mGFP
Chloramphenicol
CMV Promoter
GFP tag
Transient
Type:
ORF
Application:
Protein Expression
Gene:
Janus Kinase 1 (JAK1)
Species:
Human
Vector type:
Lentiviral Vector
Resistance Gene:
Chloramphenicol
Promoter:
CMV Promoter
Fusion Tag:
GFP tag
Expression:
Transient
Catalog No. ABIN6413930
$2,035.44
Plus shipping costs $50.00, if applicable $20.00 dry ice
Delivery in 21 to 27 Business Days
OriGene rc213878l1v
ORF
PExp
Lentiviral Vector
pLenti-C-Myc-DDK
Chloramphenicol
CMV Promoter
Myc-DYKDDDDK Tag
Transient
Type:
ORF
Application:
Protein Expression
Gene:
Janus Kinase 1 (JAK1)
Species:
Human
Vector type:
Lentiviral Vector
Resistance Gene:
Chloramphenicol
Promoter:
CMV Promoter
Fusion Tag:
Myc-DYKDDDDK Tag
Expression:
Transient
Catalog No. ABIN6413929
$2,035.44
Plus shipping costs $50.00, if applicable $20.00 dry ice
Delivery in 21 to 27 Business Days
ORF
Clon
Gateway Cloning Vector
pDONR223
Spectinomycin
unconjugated
Type:
ORF
Application:
Cloning
Gene:
Janus Kinase 1 (JAK1)
Gene ID:
3716 (Human, JAK1)
Vector type:
Gateway Cloning Vector
Resistance Gene:
Spectinomycin
Catalog No. ABIN5325645
$258.54
Plus shipping costs $50.00
Delivery in 15 to 19 Business Days
OriGene tl320394
shRNA
RNAi
Lentiviral Vector
pGFP-C-shLenti
Chloramphenicol
U6 Promoter
GFP tag
Transient
Type:
shRNA
Application:
RNA Interference
Gene:
Janus Kinase 1 (JAK1)
Species:
Human
Vector type:
Lentiviral Vector
Resistance Gene:
Chloramphenicol
Selection Marker:
Puromycin
Promoter:
U6 Promoter
Fusion Tag:
GFP tag
Expression:
Transient, Stable
Catalog No. ABIN3764523
$1,002.87
Plus shipping costs $50.00
Delivery in 16 to 17 Business Days
OriGene tf320394
shRNA
RNAi
Retroviral Vector
pRFP-C-RS
Chloramphenicol
U6 Promoter
RFP tag
Transient
Type:
shRNA
Application:
RNA Interference
Gene:
Janus Kinase 1 (JAK1)
Species:
Human
Vector type:
Retroviral Vector
Resistance Gene:
Chloramphenicol
Selection Marker:
Puromycin
Promoter:
U6 Promoter
Fusion Tag:
RFP tag
Expression:
Transient, Stable
Catalog No. ABIN3723847
$874.17
Plus shipping costs $50.00
Delivery in 4 to 9 Business Days
OriGene tf511227
shRNA
RNAi
Retroviral Vector
pRFP-C-RS
Chloramphenicol
U6 Promoter
RFP tag
Transient
Type:
shRNA
Application:
RNA Interference
Gene:
Janus Kinase 1 (JAK1)
Species:
Mouse
Vector type:
Retroviral Vector
Resistance Gene:
Chloramphenicol
Selection Marker:
Puromycin
Promoter:
U6 Promoter
Fusion Tag:
RFP tag
Expression:
Transient, Stable
Catalog No. ABIN3673536
$707.85
Plus shipping costs $50.00
Delivery in 16 to 17 Business Days
OriGene tg511227
shRNA
RNAi
Retroviral Vector
pGFP-V-RS
Kanamycin
U6 Promoter
GFP tag
Transient
Type:
shRNA
Application:
RNA Interference
Gene:
Janus Kinase 1 (JAK1)
Species:
Mouse
Vector type:
Retroviral Vector
Resistance Gene:
Kanamycin
Selection Marker:
Puromycin
Promoter:
U6 Promoter
Fusion Tag:
GFP tag
Expression:
Transient, Stable
Catalog No. ABIN3693234
$874.17
Plus shipping costs $50.00
Delivery in 4 to 9 Business Days
OriGene tg320394
shRNA
RNAi
Retroviral Vector
pGFP-V-RS
Kanamycin
U6 Promoter
GFP tag
Transient
Type:
shRNA
Application:
RNA Interference
Gene:
Janus Kinase 1 (JAK1)
Species:
Human
Vector type:
Retroviral Vector
Resistance Gene:
Kanamycin
Selection Marker:
Puromycin
Promoter:
U6 Promoter
Fusion Tag:
GFP tag
Expression:
Transient, Stable
Catalog No. ABIN3744185
$874.17
Plus shipping costs $50.00
Delivery in 4 to 9 Business Days
OriGene tr320394
shRNA
RNAi
Retroviral Vector
pRS
Ampicillin
U6 Promoter
unconjugated
Transient
Type:
shRNA
Application:
RNA Interference
Gene:
Janus Kinase 1 (JAK1)
Species:
Human
Vector type:
Retroviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter
Expression:
Transient, Stable
Catalog No. ABIN3661282
$874.17
Plus shipping costs $50.00
Delivery in 4 to 9 Business Days
OriGene tg711879
shRNA
RNAi
Retroviral Vector
pGFP-V-RS
Kanamycin
U6 Promoter
GFP tag
Transient
Type:
shRNA
Application:
RNA Interference
Gene:
Janus Kinase 1 (JAK1)
Species:
Rat
Vector type:
Retroviral Vector
Resistance Gene:
Kanamycin
Selection Marker:
Puromycin
Promoter:
U6 Promoter
Fusion Tag:
GFP tag
Expression:
Transient, Stable
Catalog No. ABIN3506084
$707.85
Plus shipping costs $50.00
Delivery in 16 to 17 Business Days
Synonyms and alternative names related to JAK1
Janus kinase 1 (JAK1)
Janus kinase 1 (Jak1)
Janus kinase 1 (jak1)
tyrosine-protein kinase JAK1 (LOC100286690)
AA960307
C130039L05Rik
jak1
JAK1A
JAK1B
JTK3
wu:fb93e10
Gene-IDs for different species
Protein level used designations for JAK1
tyrosine-protein kinase JAK1
JAK-1
etID309794.6
fb93e10
jak-1
jak1 kinase
Janus protein tyrosine kinase 1
Janus kinase 1 (a protein tyrosine kinase)
tyrosine kinase JAK1
protein tyrosine kinase
Janus kinase 1
Tyrosine-protein kinase Jak1
tyrosine-protein kinase JAK1-like
Other products related to JAK1 such as antibodies, ELISA kits and high-purity proteins are available on our partner website
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