LATS1 (LATS, Large Tumor Suppressor, Homolog 1 (Drosophila), LATS1)
Short Description: The protein encoded by this gene is a putative serine/threonine kinase that localizes to the mitotic apparatus and complexes with cell cycle controller CDC2 kinase in early mitosis. The protein is phosphorylated in a cell-cycle dependent manner, with late prophase phosphorylation remaining through metaphase. The N-terminal region of the protein binds CDC2 to form a complex showing reduced H1 histone kinase activity, indicating a role as a negative regulator of CDC2/cyclin A. In addition, the C-terminal kinase domain binds to its own N-terminal region, suggesting potential negative regulation through interference with complex formation via intramolecular binding. Biochemical and genetic data suggest a role as a tumor suppressor. This is supported by studies in knockout mice showing development of soft-tissue sarcomas, ovarian stromal cell tumors and a high sensitivity to carcinogenic treatments.
More information related to gene LATS1.
More information related to gene LATS1.
Products related to LATS1 Gene:
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62 results
OriGene sc117200
cDNA
PExp
Mammalian Expression Vector
pCMV6-XL4
Ampicillin
Enhanced CMV Promoter
unconjugated
Transient
1
1
- Type:
- cDNA
- Application:
- Protein Expression
- Gene:
- LATS, Large Tumor Suppressor, Homolog 1 (Drosophila) (LATS1)
- NCBI Accession:
- NM_004690,NP_004681
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-XL4
- Resistance Gene:
- Ampicillin
- Promoter:
- Enhanced CMV Promoter, T7 Promoter
- Expression:
- Transient
Catalog No. ABIN3378652
$1,461.24
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 4 to 9 Business Days
OriGene sc323703
cDNA
PExp
Mammalian Expression Vector
pCMV6-XL4
Ampicillin
Enhanced CMV Promoter
unconjugated
Transient
1
- Type:
- cDNA
- Application:
- Protein Expression
- Gene:
- LATS, Large Tumor Suppressor, Homolog 1 (Drosophila) (LATS1)
- NCBI Accession:
- NM_004690,NP_004681
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-XL4
- Resistance Gene:
- Ampicillin
- Promoter:
- Enhanced CMV Promoter, T7 Promoter
- Expression:
- Transient
Catalog No. ABIN3381425
$1,461.24
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 21 to 22 Business Days
OriGene rc234723
ORF
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
CMV Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- LATS, Large Tumor Suppressor, Homolog 1 (Drosophila) (LATS1)
- NCBI Accession:
- NM_001270519,NP_001257448
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-Entry
- Resistance Gene:
- Kanamycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN5332562
$688.05
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 71 to 72 Business Days
OriGene rr217489
ORF
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
CMV Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- LATS, Large Tumor Suppressor, Homolog 1 (Drosophila) (LATS1)
- Species:
- Rat
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-Entry
- Resistance Gene:
- Kanamycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN5332563
$1,071.18
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 21 to 22 Business Days
ORF
PExp
Mammalian Expression Vector
pcDNA3.1+C-(K)-DYK
Ampicillin
CMV Promoter
DYKDDDDK Tag
Transient
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- LATS, Large Tumor Suppressor, Homolog 1 (Drosophila) (LATS1)
- NCBI Accession:
- NM_001270519
- Gene ID:
- 9113 (Human, LATS1)
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pcDNA3.1+C-(K)-DYK
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Neomycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- DYKDDDDK Tag
- Expression:
- Transient, Stable
Catalog No. ABIN4943443
$559.00
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 31 to 32 Business Days
ORF
PExp
Mammalian Expression Vector
pcDNA3.1+C-(K)-DYK
Ampicillin
CMV Promoter
DYKDDDDK Tag
Transient
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- LATS, Large Tumor Suppressor, Homolog 1 (Drosophila) (LATS1)
- NCBI Accession:
- NM_004690
- Gene ID:
- 9113 (Human, LATS1)
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pcDNA3.1+C-(K)-DYK
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Neomycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- DYKDDDDK Tag
- Expression:
- Transient, Stable
Catalog No. ABIN4945737
$799.00
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 2 to 5 Business Days
OriGene rg234723
ORF
PExp
Mammalian Expression Vector
pCMV6-AC-GFP
Ampicillin
CMV Promoter
GFP tag
Stable
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- LATS, Large Tumor Suppressor, Homolog 1 (Drosophila) (LATS1)
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-AC-GFP
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Neomycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- GFP tag
- Expression:
- Stable, Transient
Catalog No. ABIN5332561
$886.05
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 71 to 72 Business Days
OriGene rc223650
ORF
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
CMV Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- LATS, Large Tumor Suppressor, Homolog 1 (Drosophila) (LATS1)
- NCBI Accession:
- NM_004690,NP_004681
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-Entry
- Resistance Gene:
- Kanamycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN5437011
$1,460.25
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 8 to 11 Business Days
OriGene rc223650l1
ORF
PExp
Lentiviral Vector
pLenti-C-Myc-DDK
Chloramphenicol
CMV Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- LATS, Large Tumor Suppressor, Homolog 1 (Drosophila) (LATS1)
- NCBI Accession:
- NM_004690,NP_004681
- Species:
- Human
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-C-Myc-DDK
- Resistance Gene:
- Chloramphenicol
- Promoter:
- CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN5437013
$1,757.25
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 8 to 11 Business Days
OriGene rc223650l2
ORF
PExp
Lentiviral Vector
pLenti-C-mGFP
Chloramphenicol
CMV Promoter
GFP tag
Transient
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- LATS, Large Tumor Suppressor, Homolog 1 (Drosophila) (LATS1)
- NCBI Accession:
- NM_004690,NP_004681
- Species:
- Human
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-C-mGFP
- Resistance Gene:
- Chloramphenicol
- Promoter:
- CMV Promoter
- Fusion Tag:
- GFP tag
- Expression:
- Transient
Catalog No. ABIN5437012
$1,757.25
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 6 to 9 Business Days
Synonyms and alternative names related to LATS1
- large tumor suppressor kinase 1 (LATS1)
- large tumor suppressor (Lats1)
- large tumor suppressor kinase 1 (lats1)
- large tumor suppressor kinase 1 (Lats1)
- large tumor suppressor kinase 1 S homeolog (lats1.S)
- AW208599
- Lats
- lats1
- RGD1564085
- si:dkey-181i3.5
- WARTS
- warts
- wts
- wu:fc19a11
- zgc:123219
Gene-IDs for different species
Protein level used designations for LATS1
- LATS (large tumor suppressor, Drosophila) homolog 1
- LATS, large tumor suppressor, homolog 1
- WARTS protein kinase
- h-warts
- large tumor suppressor homolog 1
- serine/threonine-protein kinase LATS1
- large tumor supressor, homolog 1
- large tumor suppressor 1
- large tumor suppressor
- LATS homolog 1
- LATS, large tumor suppressor, homolog 1 (Drosophila)
- serine/threonine-protein kinase LATS1-like
- large tumor suppressor kinase 1 S homeolog
Proteomics products related to LATS1 Gene
Other products related to LATS1 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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