LIG4 (Ligase IV, DNA, ATP-Dependent, LIG4)
Short Description: The protein encoded by this gene is a DNA ligase that joins single-strand breaks in a double-stranded polydeoxynucleotide in an ATP-dependent reaction. This protein is essential for V(D)J recombination and DNA double-strand break (DSB) repair through nonhomologous end joining (NHEJ). This protein forms a complex with the X-ray repair cross complementing protein 4 (XRCC4), and further interacts with the DNA-dependent protein kinase (DNA-PK). Both XRCC4 and DNA-PK are known to be required for NHEJ. The crystal structure of the complex formed by this protein and XRCC4 has been resolved. Defects in this gene are the cause of LIG4 syndrome. Alternatively spliced transcript variants encoding the same protein have been observed. [provided by RefSeq, Jul 2008].
More information related to gene LIG4.
More information related to gene LIG4.
Products related to LIG4 Gene:
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65 results
OriGene tr704686
shRNA
RNAi
Retroviral Vector
pRS
Ampicillin
U6 Promoter
unconjugated
Transient
1
- Type:
- shRNA
- Application:
- RNA Interference
- Gene:
- Ligase IV, DNA, ATP-Dependent (LIG4)
- Species:
- Rat
- Vector type:
- Retroviral Vector
- Vector backbone:
- pRS
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Puromycin
- Promoter:
- U6 Promoter
- Expression:
- Transient, Stable
Catalog No. ABIN3444461
$874.17
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 16 to 17 Business Days
OriGene tl508237
shRNA
RNAi
Lentiviral Vector
pGFP-C-shLenti
Chloramphenicol
U6 Promoter
GFP tag
Transient
1
- Type:
- shRNA
- Application:
- RNA Interference
- Gene:
- Ligase IV, DNA, ATP-Dependent (LIG4)
- Species:
- Mouse
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pGFP-C-shLenti
- Resistance Gene:
- Chloramphenicol
- Selection Marker:
- Puromycin
- Promoter:
- U6 Promoter
- Fusion Tag:
- GFP tag
- Expression:
- Transient, Stable
Catalog No. ABIN3520851
$1,002.87
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 16 to 17 Business Days
OriGene tg704686
shRNA
RNAi
Retroviral Vector
pGFP-V-RS
Kanamycin
U6 Promoter
GFP tag
Transient
1
- Type:
- shRNA
- Application:
- RNA Interference
- Gene:
- Ligase IV, DNA, ATP-Dependent (LIG4)
- Species:
- Rat
- Vector type:
- Retroviral Vector
- Vector backbone:
- pGFP-V-RS
- Resistance Gene:
- Kanamycin
- Selection Marker:
- Puromycin
- Promoter:
- U6 Promoter
- Fusion Tag:
- GFP tag
- Expression:
- Transient, Stable
Catalog No. ABIN3498907
$707.85
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 16 to 17 Business Days
OriGene sc316278
cDNA
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
Enhanced CMV Promoter
unconjugated
Transient
1
- Type:
- cDNA
- Application:
- Protein Expression
- Gene:
- Ligase IV, DNA, ATP-Dependent (LIG4)
- NCBI Accession:
- NM_001098268,NP_001091738
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-Entry
- Resistance Gene:
- Kanamycin
- Selection Marker:
- Neomycin
- Promoter:
- Enhanced CMV Promoter
- Expression:
- Transient
Catalog No. ABIN3302190
$908.82
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 21 to 22 Business Days
OriGene sc308332
cDNA
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
Enhanced CMV Promoter
unconjugated
Transient
1
- Type:
- cDNA
- Application:
- Protein Expression
- Gene:
- Ligase IV, DNA, ATP-Dependent (LIG4)
- NCBI Accession:
- NM_206937,NP_996820
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-Entry
- Resistance Gene:
- Kanamycin
- Selection Marker:
- Neomycin
- Promoter:
- Enhanced CMV Promoter
- Expression:
- Transient
Catalog No. ABIN3302189
$908.82
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 21 to 22 Business Days
OriGene sr421144
RNAi
LIG4
Species: Mouse
HPLC purified
- Application:
- RNA Interference
- Gene:
- Ligase IV, DNA, ATP-Dependent
- Species:
- Mouse
- Purification:
- HPLC purified
Catalog No. ABIN3348011
$512.82
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 16 to 17 Business Days
OriGene sr502221
RNAi
LIG4
Species: Rat
HPLC purified
- Application:
- RNA Interference
- Gene:
- Ligase IV, DNA, ATP-Dependent
- Species:
- Rat
- Purification:
- HPLC purified
Catalog No. ABIN3352443
$512.82
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 16 to 17 Business Days
OriGene kn509282
gRNA + Cas9
GEEN
Mammalian Expression Vector
pCas-Guide
Ampicillin
U6 Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- gRNA + Cas9
- Application:
- Genome Editing with Engineered Nucleases
- Gene:
- Ligase IV, DNA, ATP-Dependent (LIG4)
- Species:
- Mouse
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCas-Guide
- Resistance Gene:
- Ampicillin
- Promoter:
- U6 Promoter, Enhanced CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN3241147
$1,640.43
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 21 to 22 Business Days
OriGene kn406295
gRNA + Cas9
GEEN
Mammalian Expression Vector
pCas-Guide
Ampicillin
U6 Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- gRNA + Cas9
- Application:
- Genome Editing with Engineered Nucleases
- Gene:
- Ligase IV, DNA, ATP-Dependent (LIG4)
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCas-Guide
- Resistance Gene:
- Ampicillin
- Promoter:
- U6 Promoter, Enhanced CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN3241146
$1,640.43
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 21 to 22 Business Days
OriGene mc222564
cDNA
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
Enhanced CMV Promoter
unconjugated
Transient
1
- Type:
- cDNA
- Application:
- Protein Expression
- Gene:
- Ligase IV, DNA, ATP-Dependent (LIG4)
- NCBI Accession:
- NM_176953,NP_795927
- Species:
- Mouse
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-Entry
- Resistance Gene:
- Kanamycin
- Selection Marker:
- Neomycin
- Promoter:
- Enhanced CMV Promoter
- Expression:
- Transient
Catalog No. ABIN3328216
$826.65
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 31 to 32 Business Days
Synonyms and alternative names related to LIG4
- ligase IV, DNA, ATP-dependent (lig4)
- DNA ligase 4 (LIG4)
- DNA ligase 4 (LOC100212302)
- DNA ligase 4 (CpipJ_CPIJ005161)
- DNA ligase 4 (PTRG_09982)
- DNA ligase 4 (MCYG_05151)
- DNA ligase 4 (LOC657210)
- ATP-dependent DNA ligase implicated in dsDNA break repair via nonhomologous end-joining (LIG4)
- DNA ligase IV (ATLIG4)
- ligase IV, DNA, ATP-dependent L homeolog (lig4.L)
- ligase IV, DNA, ATP-dependent (Lig4)
- DNA ligase 4 (Lig4)
- 5830471N16Rik
- DNA LIGASE IV
- DNL4
- lig4
- LIG4
- lig4-A
- tiny
- zgc:165595
Gene-IDs for different species
Protein level used designations for LIG4
- DNA ligase 4
- ligase IV, DNA, ATP-dependent
- DNA ligase IV
- DNA ligase (ATP) 4
- GLEAN_12219
- ligase4-like protein
- DNA ligase 4-like
- dsDNA break repair ligase
- polydeoxyribonucleotide synthase [ATP] 4
- DNA joinase
- DNA repair enzyme
- polynucleotide ligase
- sealase
Proteomics products related to LIG4 Gene
Other products related to LIG4 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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