LIN28A (Lin-28 Homolog A (C. Elegans), LIN28A)
Short Description: Acts as a 'translational enhancer', driving specific mRNAs to polysomes and thus increasing the efficiency of protein synthesis. Its association with the translational machinery and target mRNAs results in an increased number of initiation events per molecule of mRNA and, indirectly, in stabilizing the mRNAs. Acts as a suppressor of microRNA (miRNA) biogenesis by specifically binding the precursor let-7 (pre-let-7), a miRNA precursor. Acts by binding pre-let-7 and recruiting an uridylyltransferase, leading to the terminal uridylation of pre- let-7. Uridylated pre-let-7 miRNAs fail to be processed by Dicer and undergo degradation. Specifically recognizes the 5'-GGAG-3' motif in the terminal loop of pre-let-7. Also recognizes and binds non pre-let-7 pre-miRNAs that contain the 5'-GGAG-3' motif in the terminal loop, leading to their terminal uridylation and subsequent degradation (By similarity).
More information related to gene LIN28A.
More information related to gene LIN28A.
Products related to LIN28A Gene:
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58 results
OriGene tr513548
shRNA
RNAi
Retroviral Vector
pRS
Ampicillin
U6 Promoter
unconjugated
Transient
1
- Type:
- shRNA
- Application:
- RNA Interference
- Gene:
- Lin-28 Homolog A (C. Elegans) (LIN28A)
- Species:
- Mouse
- Vector type:
- Retroviral Vector
- Vector backbone:
- pRS
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Puromycin
- Promoter:
- U6 Promoter
- Expression:
- Transient, Stable
Catalog No. ABIN3546555
$874.17
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 16 to 17 Business Days
OriGene tf707772
shRNA
RNAi
Retroviral Vector
pRFP-C-RS
Chloramphenicol
U6 Promoter
RFP tag
Transient
1
- Type:
- shRNA
- Application:
- RNA Interference
- Gene:
- Lin-28 Homolog A (C. Elegans) (LIN28A)
- Species:
- Rat
- Vector type:
- Retroviral Vector
- Vector backbone:
- pRFP-C-RS
- Resistance Gene:
- Chloramphenicol
- Selection Marker:
- Puromycin
- Promoter:
- U6 Promoter
- Fusion Tag:
- RFP tag
- Expression:
- Transient, Stable
Catalog No. ABIN3488058
$707.85
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 16 to 17 Business Days
OriGene tg707772
shRNA
RNAi
Retroviral Vector
pGFP-V-RS
Kanamycin
U6 Promoter
GFP tag
Transient
1
- Type:
- shRNA
- Application:
- RNA Interference
- Gene:
- Lin-28 Homolog A (C. Elegans) (LIN28A)
- Species:
- Rat
- Vector type:
- Retroviral Vector
- Vector backbone:
- pGFP-V-RS
- Resistance Gene:
- Kanamycin
- Selection Marker:
- Puromycin
- Promoter:
- U6 Promoter
- Fusion Tag:
- GFP tag
- Expression:
- Transient, Stable
Catalog No. ABIN3501989
$707.85
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 16 to 17 Business Days
OriGene tl513548
shRNA
RNAi
Lentiviral Vector
pGFP-C-shLenti
Chloramphenicol
U6 Promoter
GFP tag
Transient
1
- Type:
- shRNA
- Application:
- RNA Interference
- Gene:
- Lin-28 Homolog A (C. Elegans) (LIN28A)
- Species:
- Mouse
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pGFP-C-shLenti
- Resistance Gene:
- Chloramphenicol
- Selection Marker:
- Puromycin
- Promoter:
- U6 Promoter
- Fusion Tag:
- GFP tag
- Expression:
- Transient, Stable
Catalog No. ABIN3526147
$1,002.87
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 16 to 17 Business Days
OriGene tl707772
shRNA
RNAi
Lentiviral Vector
pGFP-C-shLenti
Chloramphenicol
U6 Promoter
GFP tag
Transient
1
- Type:
- shRNA
- Application:
- RNA Interference
- Gene:
- Lin-28 Homolog A (C. Elegans) (LIN28A)
- Species:
- Rat
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pGFP-C-shLenti
- Resistance Gene:
- Chloramphenicol
- Selection Marker:
- Puromycin
- Promoter:
- U6 Promoter
- Fusion Tag:
- GFP tag
- Expression:
- Transient, Stable
Catalog No. ABIN3445062
$1,002.87
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 16 to 17 Business Days
OriGene tr707772
shRNA
RNAi
Retroviral Vector
pRS
Ampicillin
U6 Promoter
unconjugated
Transient
1
- Type:
- shRNA
- Application:
- RNA Interference
- Gene:
- Lin-28 Homolog A (C. Elegans) (LIN28A)
- Species:
- Rat
- Vector type:
- Retroviral Vector
- Vector backbone:
- pRS
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Puromycin
- Promoter:
- U6 Promoter
- Expression:
- Transient, Stable
Catalog No. ABIN3441176
$874.17
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 16 to 17 Business Days
OriGene sr405469
RNAi
LIN28A
Species: Mouse
HPLC purified
- Application:
- RNA Interference
- Gene:
- Lin-28 Homolog A (C. Elegans)
- Species:
- Mouse
- Purification:
- HPLC purified
Catalog No. ABIN3279450
$512.82
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 4 to 9 Business Days
OriGene kn509296
gRNA + Cas9
GEEN
Mammalian Expression Vector
pCas-Guide
Ampicillin
U6 Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- gRNA + Cas9
- Application:
- Genome Editing with Engineered Nucleases
- Gene:
- Lin-28 Homolog A (C. Elegans) (LIN28A)
- Species:
- Mouse
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCas-Guide
- Resistance Gene:
- Ampicillin
- Promoter:
- U6 Promoter, Enhanced CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN3241185
$1,640.43
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 21 to 22 Business Days
OriGene kn203397
gRNA + Cas9
GEEN
Mammalian Expression Vector
pCas-Guide
Ampicillin
U6 Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- gRNA + Cas9
- Application:
- Genome Editing with Engineered Nucleases
- Gene:
- Lin-28 Homolog A (C. Elegans) (LIN28A)
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCas-Guide
- Resistance Gene:
- Ampicillin
- Promoter:
- U6 Promoter, Enhanced CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN3241184
$1,640.43
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 21 to 22 Business Days
OriGene rn214770
cDNA
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
Enhanced CMV Promoter
unconjugated
Transient
1
- Type:
- cDNA
- Application:
- Protein Expression
- Gene:
- Lin-28 Homolog A (C. Elegans) (LIN28A)
- NCBI Accession:
- NM_001109269,NP_001102739
- Species:
- Rat
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-Entry
- Resistance Gene:
- Kanamycin
- Selection Marker:
- Neomycin
- Promoter:
- Enhanced CMV Promoter
- Expression:
- Transient
Catalog No. ABIN3328261
$326.70
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 21 to 22 Business Days
Synonyms and alternative names related to LIN28A
- lin-28 homolog A (LIN28A)
- lin-28 homolog A (C. elegans) (Lin28a)
- lin-28 homolog A S homeolog (lin28a.S)
- lin-28 homolog A (C. elegans) (lin28a)
- lin-28 homolog A (Lin28a)
- lin-28 homolog A (lin28a)
- AL024421
- CSDD1
- csdd1
- ENSMUSG00000070700
- Gm10299
- LIN-28
- Lin-28
- lin-28
- lin-28A
- LIN28
- Lin28
- lin28
- RGD1566408
- sb:cb650
- Tex17
- ZCCHC1
- zcchc1
- zgc:55584
Gene-IDs for different species
Protein level used designations for LIN28A
- RNA-binding protein LIN-28
- protein lin-28 homolog A
- zinc finger CCHC domain-containing protein 1
- zinc finger, CCHC domain containing 1
- testis expressed gene 17
- testis-expressed protein 17
- RNA-binding protein LIN-28A
- lin-28A
- RNA-binding protein lin-28
- Lin-28.1
- lin-28 homolog A (C. elegans)
- lin-28-like
Proteomics products related to LIN28A Gene
Other products related to LIN28A such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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