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MAP3K3 (Mitogen-Activated Protein Kinase Kinase Kinase 3, MAP3K3)

Short Description: This gene product is a 626-amino acid polypeptide that is 96.5% identical to mouse Mekk3. Its catalytic domain is closely related to those of several other kinases, including mouse Mekk2, tobacco NPK, and yeast Ste11. Northern blot analysis revealed a 4.6-kb transcript that appears to be ubiquitously expressed. This protein directly regulates the stress-activated protein kinase (SAPK) and extracellular signal-regulated protein kinase (ERK) pathways by activating SEK and MEK1/2 respectively\; it does not regulate the p38 pathway. In cotransfection assays, it enhanced transcription from a nuclear factor kappa-B (NFKB)-dependent reporter gene, consistent with a role in the SAPK pathway. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008].
More information related to gene MAP3K3.

Products related to MAP3K3 Gene:

61 results

OriGene sc323554 cDNA PExp Mammalian Expression Vector pCMV6-XL5 Ampicillin Enhanced CMV Promoter unconjugated Transient
Type:
cDNA
Application:
Protein Expression
Gene:
Mitogen-Activated Protein Kinase Kinase Kinase 3 (MAP3K3)
NCBI Accession:
NM_002401,NP_002392
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-XL5
Resistance Gene:
Ampicillin
Promoter:
Enhanced CMV Promoter, T7 Promoter
Expression:
Transient
Catalog No. ABIN3390706
$578.16
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 4 to 9 Business Days
OriGene rr213604 ORF PExp Mammalian Expression Vector pCMV6-Entry Kanamycin CMV Promoter Myc-DYKDDDDK Tag Transient
Type:
ORF
Application:
Protein Expression
Gene:
Mitogen-Activated Protein Kinase Kinase Kinase 3 (MAP3K3)
NCBI Accession:
NM_001107058,NP_001100528
Species:
Rat
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-Entry
Resistance Gene:
Kanamycin
Promoter:
CMV Promoter
Fusion Tag:
Myc-DYKDDDDK Tag
Expression:
Transient
Catalog No. ABIN5404874
$634.59
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 21 to 22 Business Days
OriGene rn213604 cDNA PExp Mammalian Expression Vector pCMV6-Entry Kanamycin Enhanced CMV Promoter unconjugated Transient
Type:
cDNA
Application:
Protein Expression
Gene:
Mitogen-Activated Protein Kinase Kinase Kinase 3 (MAP3K3)
NCBI Accession:
NM_001107058,NP_001100528
Species:
Rat
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-Entry
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
Enhanced CMV Promoter
Expression:
Transient
Catalog No. ABIN3329678
$635.58
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 21 to 22 Business Days
OriGene sc310188 cDNA PExp Mammalian Expression Vector pCMV6-Entry Kanamycin Enhanced CMV Promoter unconjugated Transient
Type:
cDNA
Application:
Protein Expression
Gene:
Mitogen-Activated Protein Kinase Kinase Kinase 3 (MAP3K3)
NCBI Accession:
NM_203351,NP_976226
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-Entry
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
Enhanced CMV Promoter
Expression:
Transient
Catalog No. ABIN3302425
$667.26
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 21 to 22 Business Days
OriGene tg502596 shRNA RNAi Retroviral Vector pGFP-V-RS Kanamycin U6 Promoter GFP tag Transient
Type:
shRNA
Application:
RNA Interference
Gene:
Mitogen-Activated Protein Kinase Kinase Kinase 3 (MAP3K3)
Species:
Mouse
Vector type:
Retroviral Vector
Vector backbone:
pGFP-V-RS
Resistance Gene:
Kanamycin
Selection Marker:
Puromycin
Promoter:
U6 Promoter
Fusion Tag:
GFP tag
Expression:
Transient, Stable
Catalog No. ABIN3684633
$707.85
Plus shipping costs $50.00
1 kit
Shipping to: United States
Delivery in 16 to 17 Business Days
OriGene tg320415 shRNA RNAi Retroviral Vector pGFP-V-RS Kanamycin U6 Promoter GFP tag Transient
Type:
shRNA
Application:
RNA Interference
Gene:
Mitogen-Activated Protein Kinase Kinase Kinase 3 (MAP3K3)
Species:
Human
Vector type:
Retroviral Vector
Vector backbone:
pGFP-V-RS
Resistance Gene:
Kanamycin
Selection Marker:
Puromycin
Promoter:
U6 Promoter
Fusion Tag:
GFP tag
Expression:
Transient, Stable
Catalog No. ABIN3744206
$707.85
Plus shipping costs $50.00
1 kit
Shipping to: United States
Delivery in 16 to 17 Business Days
OriGene tf705630 shRNA RNAi Retroviral Vector pRFP-C-RS Chloramphenicol U6 Promoter RFP tag Transient
Type:
shRNA
Application:
RNA Interference
Gene:
Mitogen-Activated Protein Kinase Kinase Kinase 3 (MAP3K3)
Species:
Rat
Vector type:
Retroviral Vector
Vector backbone:
pRFP-C-RS
Resistance Gene:
Chloramphenicol
Selection Marker:
Puromycin
Promoter:
U6 Promoter
Fusion Tag:
RFP tag
Expression:
Transient, Stable
Catalog No. ABIN3485920
$707.85
Plus shipping costs $50.00
1 kit
Shipping to: United States
Delivery in 16 to 17 Business Days
OriGene tg705630 shRNA RNAi Retroviral Vector pGFP-V-RS Kanamycin U6 Promoter GFP tag Transient
Type:
shRNA
Application:
RNA Interference
Gene:
Mitogen-Activated Protein Kinase Kinase Kinase 3 (MAP3K3)
Species:
Rat
Vector type:
Retroviral Vector
Vector backbone:
pGFP-V-RS
Resistance Gene:
Kanamycin
Selection Marker:
Puromycin
Promoter:
U6 Promoter
Fusion Tag:
GFP tag
Expression:
Transient, Stable
Catalog No. ABIN3499851
$707.85
Plus shipping costs $50.00
1 kit
Shipping to: United States
Delivery in 16 to 17 Business Days
OriGene tf320415 shRNA RNAi Retroviral Vector pRFP-C-RS Chloramphenicol U6 Promoter RFP tag Transient
Type:
shRNA
Application:
RNA Interference
Gene:
Mitogen-Activated Protein Kinase Kinase Kinase 3 (MAP3K3)
Species:
Human
Vector type:
Retroviral Vector
Vector backbone:
pRFP-C-RS
Resistance Gene:
Chloramphenicol
Selection Marker:
Puromycin
Promoter:
U6 Promoter
Fusion Tag:
RFP tag
Expression:
Transient, Stable
Catalog No. ABIN3723868
$874.17
Plus shipping costs $50.00
1 kit
Shipping to: United States
Delivery in 4 to 9 Business Days
OriGene tr320415 shRNA RNAi Retroviral Vector pRS Ampicillin U6 Promoter unconjugated Transient
Type:
shRNA
Application:
RNA Interference
Gene:
Mitogen-Activated Protein Kinase Kinase Kinase 3 (MAP3K3)
Species:
Human
Vector type:
Retroviral Vector
Vector backbone:
pRS
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter
Expression:
Transient, Stable
Catalog No. ABIN3661303
$874.17
Plus shipping costs $50.00
1 kit
Shipping to: United States
Delivery in 16 to 17 Business Days
  • Type
    • Plasmid
    • Primer
  • Supplier
    • antibodies-online
    • OriGene
    • GenScript
    • ProteoGenix
  • Reactivity
    • Human
    • Rat
    • Mouse
  • Application
    • Protein Expression (PExp)
    • Genome Editing with Engineered Nucleases (GEEN)
    • Cloning (Clon)
    • RNA Interference (RNAi)
  • Conjugate
    • Un-conjugated
    • GFP tag
    • Myc-DYKDDDDK Tag
    • His tag
    • HA tag
    • His-GST
    • His-MBP
    • DYKDDDDK Tag
    • RFP tag
  • Vector Backbone
    • pLenti-U6-sgRNA-PGK-Neo
    • pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
    • pCMV6-Entry
    • pGFP-C-shLenti
    • pGFP-V-RS
    • pORF
    • pPB-His-GST
    • pPB-His-MBP
    • pPB-N-His
    • pPM-C-HA
    • pPM-C-His
    • pRS
    • pCMV6-AC-GFP
    • pCas-Guide
    • pLenti-C-Myc-DDK
    • pLenti-C-mGFP
    • pRFP-C-RS
    • pcDNA3.1+C-(K)-DYK
    • pCMV6-XL4
    • pCMV6-XL5
    • pDONR223
  • Vector
    • Lentiviral Vector
    • Mammalian Expression Vector
    • Bacterial Expression Vector
    • Retroviral Vector
    • Cloning Vector
    • Gateway Cloning Vector
  • Insert
    • cDNA
    • ORF
    • shRNA
    • gRNA + Cas9
    • gRNA
  • Type of Oligonucleotide
    • siRNA Oligo
  • Bacterial Resistance
    • Ampicillin
    • Kanamycin
    • Chloramphenicol
    • Spectinomycin
  • Expression Type
    • Transient
    • Stable
  • Selectable Marker
    • Neomycin
    • Puromycin
  • Promoter
    • U6 Promoter
    • CMV Promoter
    • T7 Promoter
    • Enhanced CMV Promoter
    • PGK Promoter
    • SFFV Promoter
  • Format
    • Lyophilized
    • Liquid
    • Viral Particles

Synonyms and alternative names related to MAP3K3

  • mitogen-activated protein kinase kinase kinase 3 (MAP3K3)
  • mitogen-activated protein kinase kinase kinase 3 (Map3k3)
  • mitogen activated protein kinase kinase kinase 3 (Map3k3)
  • mitogen-activated protein kinase kinase kinase 3 (map3k3)
  • mitogen-activated protein kinase kinase kinase 3 L homeolog (map3k3.L)
  • NPK1-related protein kinase 3 (NP3)
  • ANP3
  • AtANP3
  • AW548911
  • F24F17.1
  • F24F17_1
  • map3k3
  • MAPKKK3
  • mapkkk3
  • MAPKKK12
  • MEKK3
  • Mekk3
  • mekk3
  • mKIAA4031
  • NPK1-related protein kinase 3

Gene-IDs for different species

Protein level used designations for MAP3K3

  • MAP/ERK kinase kinase 3
  • MAPK/ERK kinase kinase 3
  • MEK kinase 3
  • MEKK 3
  • mitogen activated protein kinase kinase kinase 3
  • mitogen-activated protein kinase kinase kinase 3
  • mitogen-activated protein kinase kinase kinase 3 L homeolog
  • Arabidopsis NPK1-related protein kinase 3
Other products related to MAP3K3 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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