MOB1A (MOB1, Mps One Binder Kinase Activator-Like 1B, MOBKL1B)
Short Description: Activator of LATS1/2 in the Hippo signaling pathway which plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein STK3/MST2 and STK4/MST1, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Phosphorylation of YAP1 by LATS1/2 inhibits its translocation into the nucleus to regulate cellular genes important for cell proliferation, cell death, and cell migration. Stimulates the kinase activity of STK38 and STK38L. Acts cooperatively with STK3/MST2 to activate STK38 (By similarity).
More information related to gene MOB1A.
More information related to gene MOB1A.
Products related to MOB1A Gene:
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OriGene rc201487l1
ORF
PExp
Lentiviral Vector
pLenti-C-Myc-DDK
Chloramphenicol
CMV Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- MOB1, Mps One Binder Kinase Activator-Like 1B (Yeast) (MOBKL1B)
- NCBI Accession:
- NM_018221,NP_060691
- Species:
- Human
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-C-Myc-DDK
- Resistance Gene:
- Chloramphenicol
- Promoter:
- CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN5449616
$742.50
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 8 to 11 Business Days
ORF
Clon
Gateway Cloning Vector
pDONR223
Spectinomycin
unconjugated
Catalog No. ABIN5314131
$204.05
Plus shipping costs $50.00
2 μg
Shipping to:
United States
Delivery in 15 to 19 Business Days
ORF
PExp
Mammalian Expression Vector
pcDNA3.1+C-(K)-DYK
Ampicillin
CMV Promoter
DYKDDDDK Tag
Transient
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- MOB1, Mps One Binder Kinase Activator-Like 1B (MOBKL1B)
- NCBI Accession:
- NM_018221
- Gene ID:
- 55233 (Human, MOBKL1B)
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pcDNA3.1+C-(K)-DYK
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Neomycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- DYKDDDDK Tag
- Expression:
- Transient, Stable
Catalog No. ABIN4937640
OriGene sr310602
RNAi
MOBKL1B
Species: Human
HPLC purified
- Application:
- RNA Interference
- Gene:
- MOB1, Mps One Binder Kinase Activator-Like 1B
- Species:
- Human
- Purification:
- HPLC purified
Catalog No. ABIN3286637
$512.82
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 16 to 17 Business Days
Synonyms and alternative names related to MOB1A
- MOB kinase activator 1A L homeolog (mob1a.L)
- MOB kinase activator 1A (MOB1A)
- MOB kinase activator 1A (mob1a)
- MOB kinase activator 1A pseudogene (LOC712156)
- MOB kinase activator 1A (Mob1a)
- 4022402H07Rik
- C2orf6
- mats1
- MATS1
- mob1
- MOB1
- MOB1A
- mob4b
- Mob4B
- MOB4B
- MOBK1B
- mobk1b
- Mobk1b
- mobkl1b
- MOBKL1B
- Mobkl1b
- wu:fv69d04
- zgc:56189
Gene-IDs for different species
Protein level used designations for MOB1A
- MOB1, Mps One Binder kinase activator-like 1B
- Mob4B protein
- mps one binder kinase activator-like 1B
- MOB1, Mps One Binder kinase activator-like 1B (yeast)
- mats1
- mobk1b
- Mps one binder kinase activator-like 1B
- mob1 homolog 1B
- MOB1 Mps One Binder homolog A
- mob1 alpha
Proteomics products related to MOB1A Gene
Other products related to MOB1A such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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