Short Description: The protein encoded by this gene was originally identified as a 44-kD glycoprotein that interacts with the NEU/ERBB2 receptor tyrosine kinase to increase its phosphorylation on tyrosine residues. This protein is a signaling protein that mediates cell-cell interactions and plays critical roles in the growth and development of multiple organ systems. It is known that an extraordinary variety of different isoforms are produced from this gene through alternative promoter usage and splicing. These isoforms are tissue-specifically expressed and differ significantly in their structure, and thereby these isoforms are classified into types I, II, III, IV, V and VI. The gene dysregulation has been linked to diseases such as cancer, schizophrenia and bipolar disorder (BPD). [provided by RefSeq, May 2009]. More information related to gene Neuregulin 1.
Synonyms and alternative names related to Neuregulin 1
neuregulin 1 (Nrg1)
neuregulin 1 (NRG1)
histidine rich glycoprotein (HRG)
neuregulin 1 L homeolog (nrg1.L)
neuregulin 1 (nrg1)
6030402G23Rik
ARIA
D230005F13Rik
DKFZp459A1838
GGF
GGF2
GGFII
heregulin
Hgl
HGL
HRG
HRG1
HRGA
HRGalpha
MST131
NDF
NRG-1
NRG1
nrg1-A
pro-neuregulin-1
SMDF
wu:fm70e01
Gene-IDs for different species
Protein level used designations for Neuregulin 1
heregulin
pro-neuregulin-1, membrane-bound isoform
type I neuregulin 1
type III neuregulin 1
neuregulin 1
HRG-alpha
heregulin-alpha
MSTP131
glial growth factor
heregulin, alpha (45kD, ERBB2 p185-activator)
neu differentiation factor
neuregulin 1 type IV beta 1a
neuregulin 1 type IV beta 3
pro-NRG1
sensory and motor neuron derived factor
neuregulin 1 type III beta 3
membrane-bound isoform
neuregulin 1 alpha isoform
Proteomics products related to Neuregulin 1 Gene
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