NUMBL (Numb Homolog (Drosophila)-Like, NUMBL)
Short Description: Plays a role in the process of neurogenesis. Required throughout embryonic neurogenesis to maintain neural progenitor cells, also called radial glial cells (RGCs), by allowing their daughter cells to choose progenitor over neuronal cell fate. Not required for the proliferation of neural progenitor cells before the onset of embryonic neurogenesis. Also required postnatally in the subventricular zone (SVZ) neurogenesis by regulating SVZ neuroblasts survival and ependymal wall integrity. Negative regulator of NF-kappa-B signaling pathway. The inhibition of NF- kappa-B activation is mediated at least in part, by preventing MAP3K7IP2 to interact with polyubiquitin chains of TRAF6 and RIPK1 and by stimulating the 'Lys-48'-linked polyubiquitination and degradation of TRAF6 in cortical neurons.
More information related to gene NUMBL.
More information related to gene NUMBL.
Products related to NUMBL Gene:
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56 results
OriGene sr503930
RNAi
NUMBL
Species: Rat
HPLC purified
- Application:
- RNA Interference
- Gene:
- Numb Homolog (Drosophila)-Like
- Species:
- Rat
- Purification:
- HPLC purified
Catalog No. ABIN3353915
$512.82
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 16 to 17 Business Days
OriGene tl514965
shRNA
RNAi
Lentiviral Vector
pGFP-C-shLenti
Chloramphenicol
U6 Promoter
GFP tag
Transient
1
- Type:
- shRNA
- Application:
- RNA Interference
- Gene:
- Numb Homolog (Drosophila)-Like (NUMBL)
- Species:
- Mouse
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pGFP-C-shLenti
- Resistance Gene:
- Chloramphenicol
- Selection Marker:
- Puromycin
- Promoter:
- U6 Promoter
- Fusion Tag:
- GFP tag
- Expression:
- Transient, Stable
Catalog No. ABIN3527557
$1,002.87
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 16 to 17 Business Days
OriGene tl703237
shRNA
RNAi
Lentiviral Vector
pGFP-C-shLenti
Chloramphenicol
U6 Promoter
GFP tag
Transient
1
- Type:
- shRNA
- Application:
- RNA Interference
- Gene:
- Numb Homolog (Drosophila)-Like (NUMBL)
- Species:
- Rat
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pGFP-C-shLenti
- Resistance Gene:
- Chloramphenicol
- Selection Marker:
- Puromycin
- Promoter:
- U6 Promoter
- Fusion Tag:
- GFP tag
- Expression:
- Transient, Stable
Catalog No. ABIN3511395
$1,002.87
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 16 to 17 Business Days
OriGene sc336821
cDNA
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
Enhanced CMV Promoter
unconjugated
Transient
1
- Type:
- cDNA
- Application:
- Protein Expression
- Gene:
- Numb Homolog (Drosophila)-Like (NUMBL)
- NCBI Accession:
- NM_001289980,NP_001276909
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-Entry
- Resistance Gene:
- Kanamycin
- Selection Marker:
- Neomycin
- Promoter:
- Enhanced CMV Promoter
- Expression:
- Transient
Catalog No. ABIN3333083
$577.17
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 21 to 22 Business Days
OriGene rn204216
cDNA
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
Enhanced CMV Promoter
unconjugated
Transient
1
- Type:
- cDNA
- Application:
- Protein Expression
- Gene:
- Numb Homolog (Drosophila)-Like (NUMBL)
- NCBI Accession:
- NM_001033888,NP_001029060
- Species:
- Rat
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-Entry
- Resistance Gene:
- Kanamycin
- Selection Marker:
- Neomycin
- Promoter:
- Enhanced CMV Promoter
- Expression:
- Transient
Catalog No. ABIN3333081
$626.67
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 21 to 22 Business Days
OriGene sc336820
cDNA
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
Enhanced CMV Promoter
unconjugated
Transient
1
- Type:
- cDNA
- Application:
- Protein Expression
- Gene:
- Numb Homolog (Drosophila)-Like (NUMBL)
- NCBI Accession:
- NM_001289979,NP_001276908
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-Entry
- Resistance Gene:
- Kanamycin
- Selection Marker:
- Neomycin
- Promoter:
- Enhanced CMV Promoter
- Expression:
- Transient
Catalog No. ABIN3333082
$577.17
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 21 to 22 Business Days
OriGene sc314186
cDNA
PExp
Mammalian Expression Vector
pCMV6-XL5
Ampicillin
Enhanced CMV Promoter
unconjugated
Transient
1
- Type:
- cDNA
- Application:
- Protein Expression
- Gene:
- Numb Homolog (Drosophila)-Like (NUMBL)
- NCBI Accession:
- NM_004756,NP_004747
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-XL5
- Resistance Gene:
- Ampicillin
- Promoter:
- Enhanced CMV Promoter, T7 Promoter
- Expression:
- Transient
Catalog No. ABIN3391245
$562.32
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 4 to 9 Business Days
ORF
PExp
Mammalian Expression Vector
pcDNA3.1+C-(K)-DYK
Ampicillin
CMV Promoter
DYKDDDDK Tag
Transient
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Numb Homolog (Drosophila)-Like (NUMBL)
- NCBI Accession:
- NM_001289979
- Gene ID:
- 9253 (Human, NUMBL)
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pcDNA3.1+C-(K)-DYK
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Neomycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- DYKDDDDK Tag
- Expression:
- Transient, Stable
Catalog No. ABIN4937053
$439.00
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 4 to 7 Business Days
OriGene rc216869l1
ORF
PExp
Lentiviral Vector
pLenti-C-Myc-DDK
Chloramphenicol
CMV Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Numb Homolog (Drosophila)-Like (NUMBL)
- NCBI Accession:
- NM_004756,NP_004747
- Species:
- Human
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-C-Myc-DDK
- Resistance Gene:
- Chloramphenicol
- Promoter:
- CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN5453257
$858.33
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 21 to 22 Business Days
OriGene rg216869
ORF
PExp
Mammalian Expression Vector
pCMV6-AC-GFP
Ampicillin
CMV Promoter
GFP tag
Stable
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Numb Homolog (Drosophila)-Like (NUMBL)
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-AC-GFP
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Neomycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- GFP tag
- Expression:
- Stable, Transient
Catalog No. ABIN5453250
$759.33
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 21 to 22 Business Days
Synonyms and alternative names related to NUMBL
- NUMB like, endocytic adaptor protein (NUMBL)
- numb homolog-like L homeolog (numbl.L)
- NUMB-like, endocytic adaptor protein (Numbl)
- numb-like (Numbl)
- cag3a
- CAG3A
- ctg3a
- CTG3a
- nbl
- NBL
- numb
- numb-r
- NUMB-R
- numblike
- NUMBLIKE
- numbr
- NUMBR
- tnrc23
- TNRC23
Gene-IDs for different species
Protein level used designations for NUMBL
- numb homolog-like
- numb-like protein
- numb-related protein
Proteomics products related to NUMBL Gene
Other products related to NUMBL such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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