PLCE1 (Phospholipase C, epsilon 1, PLCE1)
Short Description: This gene encodes a phospholipase enzyme that catalyzes the hydrolysis of phosphatidylinositol-4,5-bisphosphate to generate two second messengers: inositol 1,4,5-triphosphate (IP3) and diacylglycerol (DAG). These second messengers subsequently regulate various processes affecting cell growth, differentiation, and gene expression. This enzyme is regulated by small monomeric GTPases of the Ras and Rho families and by heterotrimeric G proteins. In addition to its phospholipase C catalytic activity, this enzyme has an N-terminal domain with guanine nucleotide exchange (GEF) activity. Mutations in this gene cause early-onset nephrotic syndrome\; characterized by proteinuria, edema, and diffuse mesangial sclerosis or focal and segmental glomerulosclerosis. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Sep 2009].
More information related to gene PLCE1.
More information related to gene PLCE1.
Products related to PLCE1 Gene:
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59 results
OriGene sr514682
RNAi
PLCE1
Species: Rat
HPLC purified
- Application:
- RNA Interference
- Gene:
- Phospholipase C, epsilon 1
- Species:
- Rat
- Purification:
- HPLC purified
Catalog No. ABIN3316103
$512.82
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 16 to 17 Business Days
OriGene tr712126
shRNA
RNAi
Retroviral Vector
pRS
Ampicillin
U6 Promoter
unconjugated
Transient
1
- Type:
- shRNA
- Application:
- RNA Interference
- Gene:
- Phospholipase C, epsilon 1 (PLCE1)
- Species:
- Rat
- Vector type:
- Retroviral Vector
- Vector backbone:
- pRS
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Puromycin
- Promoter:
- U6 Promoter
- Expression:
- Transient, Stable
Catalog No. ABIN3437012
$874.17
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 16 to 17 Business Days
OriGene sr423455
RNAi
PLCE1
Species: Mouse
HPLC purified
- Application:
- RNA Interference
- Gene:
- Phospholipase C, epsilon 1
- Species:
- Mouse
- Purification:
- HPLC purified
Catalog No. ABIN3350299
$512.82
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 16 to 17 Business Days
OriGene kn513419
gRNA + Cas9
GEEN
Mammalian Expression Vector
pCas-Guide
Ampicillin
U6 Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- gRNA + Cas9
- Application:
- Genome Editing with Engineered Nucleases
- Gene:
- Phospholipase C, epsilon 1 (PLCE1)
- Species:
- Mouse
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCas-Guide
- Resistance Gene:
- Ampicillin
- Promoter:
- U6 Promoter, Enhanced CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN3230946
$1,640.43
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 21 to 22 Business Days
OriGene kn413202
gRNA + Cas9
GEEN
Mammalian Expression Vector
pCas-Guide
Ampicillin
U6 Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- gRNA + Cas9
- Application:
- Genome Editing with Engineered Nucleases
- Gene:
- Phospholipase C, epsilon 1 (PLCE1)
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCas-Guide
- Resistance Gene:
- Ampicillin
- Promoter:
- U6 Promoter, Enhanced CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN3230945
$1,640.43
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 21 to 22 Business Days
OriGene mc225255
cDNA
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
Enhanced CMV Promoter
unconjugated
Transient
1
- Type:
- cDNA
- Application:
- Protein Expression
- Gene:
- Phospholipase C, epsilon 1 (PLCE1)
- NCBI Accession:
- NM_019588,NP_062534
- Species:
- Mouse
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-Entry
- Resistance Gene:
- Kanamycin
- Selection Marker:
- Neomycin
- Promoter:
- Enhanced CMV Promoter
- Expression:
- Transient
Catalog No. ABIN3364758
$2,051.28
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 61 to 62 Business Days
OriGene rn214972
cDNA
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
Enhanced CMV Promoter
unconjugated
Transient
1
- Type:
- cDNA
- Application:
- Protein Expression
- Gene:
- Phospholipase C, epsilon 1 (PLCE1)
- NCBI Accession:
- NM_053758,NP_446210
- Species:
- Rat
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-Entry
- Resistance Gene:
- Kanamycin
- Selection Marker:
- Neomycin
- Promoter:
- Enhanced CMV Promoter
- Expression:
- Transient
Catalog No. ABIN3364759
$2,050.29
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 61 to 62 Business Days
OriGene sc338135
cDNA
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
Enhanced CMV Promoter
unconjugated
Transient
1
- Type:
- cDNA
- Application:
- Protein Expression
- Gene:
- Phospholipase C, epsilon 1 (PLCE1)
- NCBI Accession:
- NM_001288989,NP_001275918
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-Entry
- Resistance Gene:
- Kanamycin
- Selection Marker:
- Neomycin
- Promoter:
- Enhanced CMV Promoter
- Expression:
- Transient
Catalog No. ABIN3364760
$2,055.24
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 6 to 9 Business Days
OriGene sc327342
cDNA
PExp
Mammalian Expression Vector
pCMV6-XL5
Ampicillin
Enhanced CMV Promoter
unconjugated
Transient
1
- Type:
- cDNA
- Application:
- Protein Expression
- Gene:
- Phospholipase C, epsilon 1 (PLCE1)
- NCBI Accession:
- NM_001165979,NP_001159451
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-XL5
- Resistance Gene:
- Ampicillin
- Promoter:
- Enhanced CMV Promoter, T7 Promoter
- Expression:
- Transient
Catalog No. ABIN3391540
$1,825.56
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 41 to 42 Business Days
OriGene rc228707
ORF
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
CMV Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Phospholipase C, epsilon 1 (PLCE1)
- NCBI Accession:
- NM_001165979,NP_001159451
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-Entry
- Resistance Gene:
- Kanamycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN5361358
$1,824.57
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 41 to 42 Business Days
Synonyms and alternative names related to PLCE1
- phospholipase C, epsilon 1 (PLCE1)
- phospholipase C epsilon 1 (PLCE1)
- phospholipase C, epsilon 1 (plce1)
- phospholipase C epsilon 1 (plce1)
- phospholipase C, epsilon 1 (Plce1)
- 4933403A21Rik
- mKIAA1516
- NPHS3
- PLCE
- Plce
- PLCE1
- PLCepsilon
- PPLC
Gene-IDs for different species
Protein level used designations for PLCE1
- phospholipase C, epsilon 1
- pancreas-enriched phospholipase C
- 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase epsilon-1
- 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase epsilon-1-like
- 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1
- PLC-epsilon-1
- phosphoinositide phospholipase C-epsilon-1
- phosphoinositide-specific phospholipase C epsilon-1
- phospholipase C-epsilon-1
- phospholipase C epsilon
Proteomics products related to PLCE1 Gene
Other products related to PLCE1 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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