PTPN1 (Protein tyrosine Phosphatase, Non-Receptor Type 1, PTPN1)
Short Description: The protein encoded by this gene is the founding member of the protein tyrosine phosphatase (PTP) family, which was isolated and identified based on its enzymatic activity and amino acid sequence. PTPs catalyze the hydrolysis of the phosphate monoesters specifically on tyrosine residues. Members of the PTP family share a highly conserved catalytic motif, which is essential for the catalytic activity. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP has been shown to act as a negative regulator of insulin signaling by dephosphorylating the phosphotryosine residues of insulin receptor kinase. This PTP was also reported to dephosphorylate epidermal growth factor receptor kinase, as well as JAK2 and TYK2 kinases, which implicated the role of this PTP in cell growth control, and cell response to interferon stimulation. [provided by RefSeq, Jul 2008].
More information related to gene PTPN1.
More information related to gene PTPN1.
Products related to PTPN1 Gene:
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60 results
OriGene tr501794
shRNA
RNAi
Retroviral Vector
pRS
Ampicillin
U6 Promoter
unconjugated
Transient
1
- Type:
- shRNA
- Application:
- RNA Interference
- Gene:
- Protein tyrosine Phosphatase, Non-Receptor Type 1 (PTPN1)
- Species:
- Mouse
- Vector type:
- Retroviral Vector
- Vector backbone:
- pRS
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Puromycin
- Promoter:
- U6 Promoter
- Expression:
- Transient, Stable
Catalog No. ABIN3534136
$874.17
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 4 to 9 Business Days
OriGene tr709275
shRNA
RNAi
Retroviral Vector
pRS
Ampicillin
U6 Promoter
unconjugated
Transient
1
- Type:
- shRNA
- Application:
- RNA Interference
- Gene:
- Protein tyrosine Phosphatase, Non-Receptor Type 1 (PTPN1)
- Species:
- Rat
- Vector type:
- Retroviral Vector
- Vector backbone:
- pRS
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Puromycin
- Promoter:
- U6 Promoter
- Expression:
- Transient, Stable
Catalog No. ABIN3442673
$874.17
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 16 to 17 Business Days
OriGene sr414272
RNAi
PTPN1
Species: Mouse
HPLC purified
- Application:
- RNA Interference
- Gene:
- Protein tyrosine Phosphatase, Non-Receptor Type 1
- Species:
- Mouse
- Purification:
- HPLC purified
Catalog No. ABIN3270340
$512.82
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 4 to 9 Business Days
OriGene kn514206
gRNA + Cas9
GEEN
Mammalian Expression Vector
pCas-Guide
Ampicillin
U6 Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- gRNA + Cas9
- Application:
- Genome Editing with Engineered Nucleases
- Gene:
- Protein tyrosine Phosphatase, Non-Receptor Type 1 (PTPN1)
- Species:
- Mouse
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCas-Guide
- Resistance Gene:
- Ampicillin
- Promoter:
- U6 Promoter, Enhanced CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN3232543
$1,640.43
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 21 to 22 Business Days
OriGene kn404902
gRNA + Cas9
GEEN
Mammalian Expression Vector
pCas-Guide
Ampicillin
U6 Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- gRNA + Cas9
- Application:
- Genome Editing with Engineered Nucleases
- Gene:
- Protein tyrosine Phosphatase, Non-Receptor Type 1 (PTPN1)
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCas-Guide
- Resistance Gene:
- Ampicillin
- Promoter:
- U6 Promoter, Enhanced CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN3232542
$1,640.43
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 21 to 22 Business Days
OriGene sr505025
RNAi
PTPN1
Species: Rat
HPLC purified
- Application:
- RNA Interference
- Gene:
- Protein tyrosine Phosphatase, Non-Receptor Type 1
- Species:
- Rat
- Purification:
- HPLC purified
Catalog No. ABIN3354844
$512.82
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 16 to 17 Business Days
OriGene tf709275
shRNA
RNAi
Retroviral Vector
pRFP-C-RS
Chloramphenicol
U6 Promoter
RFP tag
Transient
1
- Type:
- shRNA
- Application:
- RNA Interference
- Gene:
- Protein tyrosine Phosphatase, Non-Receptor Type 1 (PTPN1)
- Species:
- Rat
- Vector type:
- Retroviral Vector
- Vector backbone:
- pRFP-C-RS
- Resistance Gene:
- Chloramphenicol
- Selection Marker:
- Puromycin
- Promoter:
- U6 Promoter
- Fusion Tag:
- RFP tag
- Expression:
- Transient, Stable
Catalog No. ABIN3489555
$707.85
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 16 to 17 Business Days
OriGene sc110989
cDNA
PExp
Mammalian Expression Vector
pCMV6-XL4
Ampicillin
Enhanced CMV Promoter
unconjugated
Transient
1
- Type:
- cDNA
- Application:
- Protein Expression
- Gene:
- Protein tyrosine Phosphatase, Non-Receptor Type 1 (PTPN1)
- NCBI Accession:
- NM_002827,NP_002818
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-XL4
- Resistance Gene:
- Ampicillin
- Promoter:
- Enhanced CMV Promoter, T7 Promoter
- Expression:
- Transient
Catalog No. ABIN3379607
$452.43
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 4 to 9 Business Days
OriGene rn205311
cDNA
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
Enhanced CMV Promoter
unconjugated
Transient
1
- Type:
- cDNA
- Application:
- Protein Expression
- Gene:
- Protein tyrosine Phosphatase, Non-Receptor Type 1 (PTPN1)
- NCBI Accession:
- NM_012637,NP_036769
- Species:
- Rat
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-Entry
- Resistance Gene:
- Kanamycin
- Selection Marker:
- Neomycin
- Promoter:
- Enhanced CMV Promoter
- Expression:
- Transient
Catalog No. ABIN3366362
$497.97
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 21 to 22 Business Days
OriGene sc335618
cDNA
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
Enhanced CMV Promoter
unconjugated
Transient
1
- Type:
- cDNA
- Application:
- Protein Expression
- Gene:
- Protein tyrosine Phosphatase, Non-Receptor Type 1 (PTPN1)
- NCBI Accession:
- NM_001278618,NP_001265547
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-Entry
- Resistance Gene:
- Kanamycin
- Selection Marker:
- Neomycin
- Promoter:
- Enhanced CMV Promoter
- Expression:
- Transient
Catalog No. ABIN3366363
$497.97
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 16 to 17 Business Days
Synonyms and alternative names related to PTPN1
- protein tyrosine phosphatase, non-receptor type 1 (PTPN1)
- protein tyrosine phosphatase, non-receptor type 1 (Ptpn1)
- protein tyrosine phosphatase, non-receptor type 1 (ptpn1)
- protein tyrosine phosphatase, non-receptor type 1 L homeolog (ptpn1.L)
- CPTP1
- Ptp
- PTP-1B
- PTP-HA2
- PTP1B
- ptp1b
- PTPN1
- wu:fk54h03
Gene-IDs for different species
Protein level used designations for PTPN1
- protein tyrosine phosphatase, non-receptor type 1
- tyrosine-protein phosphatase non-receptor type 1
- tyrosine-protein phosphatase non-receptor type 1-like
- protein tyrosine phosphatase, placental
- protein-tyrosine phosphatase 1B
- protein-protein-tyrosine phosphatase HA2
- protein-tyrosine phosphatase HA2
- PTP-1B
- fk54h03
- protein tyrosine phosphatase 1b
- non-receptor protein tyrosine phosphatase
- phosphoprotein phosphatase
- tyrosine phosphatase 1B
Proteomics products related to PTPN1 Gene
Other products related to PTPN1 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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