RANKL (Tumor Necrosis Factor (Ligand) Superfamily, Member 11, TNFSF11)
Short Description: This gene encodes a member of the tumor necrosis factor (TNF) cytokine family which is a ligand for osteoprotegerin and functions as a key factor for osteoclast differentiation and activation. This protein was shown to be a dentritic cell survival factor and is involved in the regulation of T cell-dependent immune response. T cell activation was reported to induce expression of this gene and lead to an increase of osteoclastogenesis and bone loss. This protein was shown to activate antiapoptotic kinase AKT/PKB through a signaling complex involving SRC kinase and tumor necrosis factor receptor-associated factor (TRAF) 6, which indicated this protein may have a role in the regulation of cell apoptosis. Targeted disruption of the related gene in mice led to severe osteopetrosis and a lack of osteoclasts. The deficient mice exhibited defects in early differentiation of T and B lymphocytes, and failed to form lobulo-alveolar mammary structures during pregnancy. Two alternatively spliced transcript variants have been found. [provided by RefSeq, Jul 2008].
More information related to gene RANKL.
More information related to gene RANKL.
Products related to RANKL Gene:
Recommended next Filters:
66 results
ORF
Clon
Gateway Cloning Vector
pDONR223
Spectinomycin
unconjugated
Catalog No. ABIN5323940
$223.79
Plus shipping costs $50.00
2 μg
Shipping to:
United States
Delivery in 15 to 19 Business Days
ORF
PExp
Mammalian Expression Vector
pcDNA3.1+C-(K)-DYK
Ampicillin
CMV Promoter
DYKDDDDK Tag
Transient
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Tumor Necrosis Factor (Ligand) Superfamily, Member 11 (TNFSF11)
- NCBI Accession:
- NM_033012
- Gene ID:
- 8600 (Human, TNFSF11)
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pcDNA3.1+C-(K)-DYK
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Neomycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- DYKDDDDK Tag
- Expression:
- Transient, Stable
Catalog No. ABIN4934454
$199.00
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 4 to 7 Business Days
ORF
PExp
Mammalian Expression Vector
pcDNA3.1+C-(K)-DYK
Ampicillin
CMV Promoter
DYKDDDDK Tag
Transient
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Tumor Necrosis Factor (Ligand) Superfamily, Member 11 (TNFSF11)
- NCBI Accession:
- NM_003701
- Gene ID:
- 8600 (Human, TNFSF11)
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pcDNA3.1+C-(K)-DYK
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Neomycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- DYKDDDDK Tag
- Expression:
- Transient, Stable
Catalog No. ABIN4934455
$309.00
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 4 to 7 Business Days
OriGene rr211558
ORF
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
CMV Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Tumor Necrosis Factor (Ligand) Superfamily, Member 11 (TNFSF11)
- NCBI Accession:
- NM_057149,NP_476490
- Species:
- Rat
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-Entry
- Resistance Gene:
- Kanamycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN5341266
$286.11
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 21 to 22 Business Days
OriGene mc209550
cDNA
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
Enhanced CMV Promoter
unconjugated
Transient
1
- Type:
- cDNA
- Application:
- Protein Expression
- Gene:
- Tumor Necrosis Factor (Ligand) Superfamily, Member 11 (TNFSF11)
- NCBI Accession:
- NP_035743
- Species:
- Mouse
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-Entry
- Resistance Gene:
- Kanamycin
- Selection Marker:
- Neomycin
- Promoter:
- Enhanced CMV Promoter
- Expression:
- Transient
Catalog No. ABIN3337195
$297.00
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 4 to 9 Business Days
OriGene sc305532
cDNA
PExp
Mammalian Expression Vector
pCMV6-XL5
Ampicillin
Enhanced CMV Promoter
unconjugated
Transient
1
- Type:
- cDNA
- Application:
- Protein Expression
- Gene:
- Tumor Necrosis Factor (Ligand) Superfamily, Member 11 (TNFSF11)
- NCBI Accession:
- NM_033012,NP_143026
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-XL5
- Resistance Gene:
- Ampicillin
- Promoter:
- Enhanced CMV Promoter, T7 Promoter
- Expression:
- Transient
Catalog No. ABIN3392790
$297.00
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 4 to 9 Business Days
OriGene rc224778
ORF
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
CMV Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Tumor Necrosis Factor (Ligand) Superfamily, Member 11 (TNFSF11)
- NCBI Accession:
- NM_033012,NP_143026
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-Entry
- Resistance Gene:
- Kanamycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN5341265
$297.00
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 8 to 11 Business Days
OriGene rn211558
cDNA
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
Enhanced CMV Promoter
unconjugated
Transient
1
- Type:
- cDNA
- Application:
- Protein Expression
- Gene:
- Tumor Necrosis Factor (Ligand) Superfamily, Member 11 (TNFSF11)
- NCBI Accession:
- NM_057149,NP_476490
- Species:
- Rat
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-Entry
- Resistance Gene:
- Kanamycin
- Selection Marker:
- Neomycin
- Promoter:
- Enhanced CMV Promoter
- Expression:
- Transient
Catalog No. ABIN3337196
$326.70
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 21 to 22 Business Days
OriGene sc123947
cDNA
PExp
Mammalian Expression Vector
pCMV6-XL4
Ampicillin
Enhanced CMV Promoter
unconjugated
Transient
1
1
- Type:
- cDNA
- Application:
- Protein Expression
- Gene:
- Tumor Necrosis Factor (Ligand) Superfamily, Member 11 (TNFSF11)
- NCBI Accession:
- NM_003701,NP_003692
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-XL4
- Resistance Gene:
- Ampicillin
- Promoter:
- Enhanced CMV Promoter, T7 Promoter
- Expression:
- Transient
Catalog No. ABIN3380408
$445.50
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 4 to 9 Business Days
OriGene rc218782
ORF
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
CMV Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Tumor Necrosis Factor (Ligand) Superfamily, Member 11 (TNFSF11)
- NCBI Accession:
- NM_003701,NP_003692
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-Entry
- Resistance Gene:
- Kanamycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN5341264
$445.50
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 8 to 11 Business Days
Synonyms and alternative names related to RANKL
- TNF superfamily member 11 (TNFSF11)
- tumor necrosis factor (ligand) superfamily, member 11 (Tnfsf11)
- TNF superfamily member 11 (Tnfsf11)
- TNF receptor superfamily member 11b (TNFRSF11B)
- TNF superfamily member 11 L homeolog (tnfsf11.L)
- CD254
- cd254
- hRANKL2
- Ly109l
- ODF
- odf
- OPG
- OPGL
- opgl
- OPTB2
- optb2
- RANKL
- rankl
- sOdf
- sodf
- TNFSF11
- tnfsf11
- TRANCE
- Trance
- trance
Gene-IDs for different species
Protein level used designations for RANKL
- TNF-related activation-induced cytokine
- osteoclast differentiation factor
- osteoprotegerin ligand
- receptor activator of nuclear factor kappa B ligand
- receptor activator of nuclear factor kappa-B ligand
- tumor necrosis factor ligand superfamily member 11
- tumor necrosis factor (ligand) superfamily, member 11
- Receptor activator of nuclear factor kappa-B ligand
- OPG ligand
- receptor activator of NF-kappaB ligand
- tumor necrosis factor-related activation-induced cytokine
- ODF
- OPGL
- TRANCE
- osteoprotegerin
- TNF superfamily member 11 L homeolog
- tumor necrosis factor superfamily member 11 L homeolog
Proteomics products related to RANKL Gene
Other products related to RANKL such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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