RECQL2 (Werner syndrome RecQ like helicase, WRN)
Short Description: This gene encodes a member of the RecQ subfamily and the DEAH (Asp-Glu-Ala-His) subfamily of DNA and RNA helicases. DNA helicases are involved in many aspects of DNA metabolism, including transcription, replication, recombination, and repair. This protein contains a nuclear localization signal in the C-terminus and shows a predominant nucleolar localization. It possesses an intrinsic 3' to 5' DNA helicase activity, and is also a 3' to 5' exonuclease. Based on interactions between this protein and Ku70/80 heterodimer in DNA end processing, this protein may be involved in the repair of double strand DNA breaks. Defects in this gene are the cause of Werner syndrome, an autosomal recessive disorder characterized by premature aging. [provided by RefSeq, Jul 2008].
More information related to gene RECQL2.
More information related to gene RECQL2.
Products related to RECQL2 Gene:
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OriGene mr226496l1v
ORF
PExp
Lentiviral Vector
pLenti-C-Myc-DDK
Chloramphenicol
CMV Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Werner syndrome RecQ like helicase (WRN)
- Species:
- Mouse
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-C-Myc-DDK
- Resistance Gene:
- Chloramphenicol
- Promoter:
- CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN6479605
$2,890.52
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200 μL
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Synonyms and alternative names related to RECQL2
- Werner syndrome RecQ like helicase (WRN)
- mediator of RNA polymerase II transcription subunit 34 (LOC9327212)
- Bloom syndrome RecQ like helicase (blm)
- Werner syndrome RecQ like helicase (Wrn)
- Werner syndrome, RecQ helicase-like L homeolog (wrn.L)
- AI846146
- ffa-1
- recq2
- RECQ3
- RECQL2
- recql2
- RECQL3
- recql3
- RGD1564788
- xBLM
- xwrn
Gene-IDs for different species
Protein level used designations for RECQL2
- DNA helicase, RecQ-like type 3
- Werner syndrome ATP-dependent helicase
- exonuclease WRN
- recQ protein-like 2
- RECQL2
- Werner syndrome ATP-dependent helicase homolog
- focus forming activity 1
- focus-forming activity 1
- Werner syndrome, RecQ helicase-like
- similar to Werner syndrome helicase homolog
Proteomics products related to RECQL2 Gene
Other products related to RECQL2 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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