RFWD2 (Ring Finger and WD Repeat Domain 2, E3 Ubiquitin Protein Ligase, RFWD2)
Short Description: E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin- conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Involved in JUN ubiquitination and degradation. Directly involved in p53 (TP53) ubiquitination and degradation, thereby abolishing p53-dependent transcription and apoptosis. Ubiquitinates p53 independently of MDM2 or RCHY1. Probably mediates E3 ubiquitin ligase activity by functioning as the essential RING domain subunit of larger E3 complexes. In contrast, it does not constitute the catalytic RING subunit in the DCX DET1-COP1 complex that negatively regulates JUN, the ubiquitin ligase activity being mediated by RBX1 (By similarity).
More information related to gene RFWD2.
More information related to gene RFWD2.
Products related to RFWD2 Gene:
Recommended next Filters:
57 results
ORF
PExp
Mammalian Expression Vector
pcDNA3.1+C-(K)-DYK
Ampicillin
CMV Promoter
DYKDDDDK Tag
Transient
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Ring Finger and WD Repeat Domain 2, E3 Ubiquitin Protein Ligase (RFWD2)
- NCBI Accession:
- NM_001286644
- Gene ID:
- 64326 (Human, RFWD2)
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pcDNA3.1+C-(K)-DYK
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Neomycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- DYKDDDDK Tag
- Expression:
- Transient, Stable
Catalog No. ABIN4935928
$319.00
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 4 to 7 Business Days
OriGene sc336432
cDNA
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
Enhanced CMV Promoter
unconjugated
Transient
1
- Type:
- cDNA
- Application:
- Protein Expression
- Gene:
- Ring Finger and WD Repeat Domain 2, E3 Ubiquitin Protein Ligase (RFWD2)
- NCBI Accession:
- NM_001286644,NP_001273573
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-Entry
- Resistance Gene:
- Kanamycin
- Selection Marker:
- Neomycin
- Promoter:
- Enhanced CMV Promoter
- Expression:
- Transient
Catalog No. ABIN3367419
$497.97
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 16 to 17 Business Days
OriGene rc238538
ORF
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
CMV Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Ring Finger and WD Repeat Domain 2, E3 Ubiquitin Protein Ligase (RFWD2)
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-Entry
- Resistance Gene:
- Kanamycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN5477125
$497.97
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 16 to 17 Business Days
OriGene sr419644
RNAi
RFWD2
Species: Mouse
HPLC purified
- Application:
- RNA Interference
- Gene:
- Ring Finger and WD Repeat Domain 2, E3 Ubiquitin Protein Ligase
- Species:
- Mouse
- Purification:
- HPLC purified
Catalog No. ABIN3262823
$512.82
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 16 to 17 Business Days
OriGene sr512902
RNAi
RFWD2
Species: Rat
HPLC purified
- Application:
- RNA Interference
- Gene:
- Ring Finger and WD Repeat Domain 2, E3 Ubiquitin Protein Ligase
- Species:
- Rat
- Purification:
- HPLC purified
Catalog No. ABIN3361609
$512.82
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 16 to 17 Business Days
OriGene sr312017
RNAi
RFWD2
Species: Human
HPLC purified
- Application:
- RNA Interference
- Gene:
- Ring Finger and WD Repeat Domain 2, E3 Ubiquitin Protein Ligase
- Species:
- Human
- Purification:
- HPLC purified
Catalog No. ABIN3288047
$512.82
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 16 to 17 Business Days
OriGene rc211483
ORF
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
CMV Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Ring Finger and WD Repeat Domain 2, E3 Ubiquitin Protein Ligase (RFWD2)
- NCBI Accession:
- NM_001001740,NP_001001740
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-Entry
- Resistance Gene:
- Kanamycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN5342480
$640.53
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 8 to 11 Business Days
OriGene rc210492
ORF
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
CMV Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Ring Finger and WD Repeat Domain 2, E3 Ubiquitin Protein Ligase (RFWD2)
- NCBI Accession:
- NM_022457,NP_071902
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-Entry
- Resistance Gene:
- Kanamycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN5342479
$662.31
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 8 to 11 Business Days
OriGene sc128099
cDNA
PExp
Mammalian Expression Vector
pCMV6-XL6
Ampicillin
Enhanced CMV Promoter
unconjugated
Transient
1
- Type:
- cDNA
- Application:
- Protein Expression
- Gene:
- Ring Finger and WD Repeat Domain 2, E3 Ubiquitin Protein Ligase (RFWD2)
- NCBI Accession:
- NM_022457,NP_071902
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-XL6
- Resistance Gene:
- Ampicillin
- Promoter:
- Enhanced CMV Promoter, SP6 Promoter
- Expression:
- Transient
Catalog No. ABIN3393753
$663.30
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 4 to 9 Business Days
OriGene sc300304
cDNA
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
Enhanced CMV Promoter
unconjugated
Transient
1
- Type:
- cDNA
- Application:
- Protein Expression
- Gene:
- Ring Finger and WD Repeat Domain 2, E3 Ubiquitin Protein Ligase (RFWD2)
- NCBI Accession:
- NM_001001740,NP_001001740
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-Entry
- Resistance Gene:
- Kanamycin
- Selection Marker:
- Neomycin
- Promoter:
- Enhanced CMV Promoter
- Expression:
- Transient
Catalog No. ABIN3304583
$705.87
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 21 to 22 Business Days
Synonyms and alternative names related to RFWD2
- ring finger and WD repeat domain 2 (RFWD2)
- ring finger and WD repeat domain 2 (Rfwd2)
- ring finger and WD repeat domain 2, E3 ubiquitin protein ligase (rfwd2)
- ring finger and WD repeat domain 2, E3 ubiquitin protein ligase L homeolog (rfwd2.L)
- ring finger and WD repeat domain 2 (rfwd2)
- AI316802
- C80879
- COP1
- Cop1
- cop1
- RFWD2
- RGD1304773
- RNF200
- rnf200
- zgc:163067
Gene-IDs for different species
Protein level used designations for RFWD2
- E3 ubiquitin-protein ligase RFWD2
- RING finger and WD repeat domain protein 2
- RING finger protein 200
- constitutive photomorphogenesis protein 1 homolog
- constitutive photomorphogenic protein (COP1)
- hCOP1
- putative ubiquitin ligase COP1
- constitutive photomorphogenic protein 1
- mCOP1
- ring finger and WD repeat domain 2
- rp11-318c24.3
Proteomics products related to RFWD2 Gene
Other products related to RFWD2 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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