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RFWD3 (Ring Finger and WD Repeat Domain 3, RFWD3)

Short Description: E3 ubiquitin-protein ligase that mediates the ubiquitination of p53/TP53 in the late response to DNA damage, and acts as a positive regulator of p53/TP53 stability, thereby regulating the G1/S DNA damage checkpoint. May act by catalyzing the formation of short polyubiquitin chains on p53/TP53 that are not targeted to the proteasome. In response to ionizing radiation, interacts with MDM2 and enhances p53/TP53 ubiquitination, possibly by restricting MDM2 from extending polyubiquitin chains on ubiquitinated p53/TP53. Plays a role in RPA-mediated DNA damage signaling and repair.
More information related to gene RFWD3.

Products related to RFWD3 Gene:

42 results

ORF Clon Gateway Cloning Vector pDONR223 Spectinomycin unconjugated
Type:
ORF
Application:
Cloning
Gene:
Ring Finger and WD Repeat Domain 3 (RFWD3)
Gene ID:
55159 (Human, RFWD3)
Vector type:
Gateway Cloning Vector
Vector backbone:
pDONR223
Resistance Gene:
Spectinomycin
Catalog No. ABIN5320121
$235.38
Plus shipping costs $50.00
2 μg
Shipping to: United States
Delivery in 15 to 19 Business Days
ORF PExp Mammalian Expression Vector pcDNA3.1+C-(K)-DYK Ampicillin CMV Promoter DYKDDDDK Tag Transient
ISO 9001:2008
Type:
ORF
Application:
Protein Expression
Gene:
Ring Finger and WD Repeat Domain 3 (RFWD3)
NCBI Accession:
NM_018124
Gene ID:
55159 (Human, RFWD3)
Vector type:
Mammalian Expression Vector
Vector backbone:
pcDNA3.1+C-(K)-DYK
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
DYKDDDDK Tag
Expression:
Transient, Stable
Catalog No. ABIN4942628
$379.00
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 31 to 32 Business Days
OriGene sc113686 cDNA PExp Mammalian Expression Vector pCMV6-XL4 Ampicillin Enhanced CMV Promoter unconjugated Transient
Type:
cDNA
Application:
Protein Expression
Gene:
Ring Finger and WD Repeat Domain 3 (RFWD3)
NCBI Accession:
NM_018124,NP_060594
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-XL4
Resistance Gene:
Ampicillin
Promoter:
Enhanced CMV Promoter, T7 Promoter
Expression:
Transient
Catalog No. ABIN3379765
$452.43
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 4 to 9 Business Days
OriGene sr420011 RNAi RFWD3 Species: Mouse HPLC purified
Application:
RNA Interference
Gene:
Ring Finger and WD Repeat Domain 3
Species:
Mouse
Purification:
HPLC purified
Catalog No. ABIN3263187
$512.82
Plus shipping costs $50.00
1 kit
Shipping to: United States
Delivery in 16 to 17 Business Days
OriGene sr310535 RNAi RFWD3 Species: Human HPLC purified
Application:
RNA Interference
Gene:
Ring Finger and WD Repeat Domain 3
Species:
Human
Purification:
HPLC purified
Catalog No. ABIN3286570
$512.82
Plus shipping costs $50.00
1 kit
Shipping to: United States
Delivery in 4 to 9 Business Days
OriGene rc209196 ORF PExp Mammalian Expression Vector pCMV6-Entry Kanamycin CMV Promoter Myc-DYKDDDDK Tag Transient
Type:
ORF
Application:
Protein Expression
Gene:
Ring Finger and WD Repeat Domain 3 (RFWD3)
NCBI Accession:
NM_018124,NP_060594
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-Entry
Resistance Gene:
Kanamycin
Promoter:
CMV Promoter
Fusion Tag:
Myc-DYKDDDDK Tag
Expression:
Transient
Catalog No. ABIN5363327
$701.91
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 8 to 11 Business Days
OriGene tg302024 shRNA RNAi Retroviral Vector pGFP-V-RS Kanamycin U6 Promoter GFP tag Transient
Type:
shRNA
Application:
RNA Interference
Gene:
Ring Finger and WD Repeat Domain 3 (RFWD3)
Species:
Human
Vector type:
Retroviral Vector
Vector backbone:
pGFP-V-RS
Resistance Gene:
Kanamycin
Selection Marker:
Puromycin
Promoter:
U6 Promoter
Fusion Tag:
GFP tag
Expression:
Transient, Stable
Catalog No. ABIN3726941
$707.85
Plus shipping costs $50.00
1 kit
Shipping to: United States
Delivery in 16 to 17 Business Days
OriGene tg510262 shRNA RNAi Retroviral Vector pGFP-V-RS Kanamycin U6 Promoter GFP tag Transient
Type:
shRNA
Application:
RNA Interference
Gene:
Ring Finger and WD Repeat Domain 3 (RFWD3)
Species:
Mouse
Vector type:
Retroviral Vector
Vector backbone:
pGFP-V-RS
Resistance Gene:
Kanamycin
Selection Marker:
Puromycin
Promoter:
U6 Promoter
Fusion Tag:
GFP tag
Expression:
Transient, Stable
Catalog No. ABIN3692271
$707.85
Plus shipping costs $50.00
1 kit
Shipping to: United States
Delivery in 16 to 17 Business Days
OriGene tf510262 shRNA RNAi Retroviral Vector pRFP-C-RS Chloramphenicol U6 Promoter RFP tag Transient
Type:
shRNA
Application:
RNA Interference
Gene:
Ring Finger and WD Repeat Domain 3 (RFWD3)
Species:
Mouse
Vector type:
Retroviral Vector
Vector backbone:
pRFP-C-RS
Resistance Gene:
Chloramphenicol
Selection Marker:
Puromycin
Promoter:
U6 Promoter
Fusion Tag:
RFP tag
Expression:
Transient, Stable
Catalog No. ABIN3672573
$707.85
Plus shipping costs $50.00
1 kit
Shipping to: United States
Delivery in 16 to 17 Business Days
OriGene sc318255 cDNA PExp Mammalian Expression Vector pCMV6-Entry Kanamycin Enhanced CMV Promoter unconjugated Transient
Type:
cDNA
Application:
Protein Expression
Gene:
Ring Finger and WD Repeat Domain 3 (RFWD3)
NCBI Accession:
NM_018124,NP_060594
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-Entry
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
Enhanced CMV Promoter
Expression:
Transient
Catalog No. ABIN3304584
$773.19
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 21 to 22 Business Days
  • Type
    • Plasmid
    • Primer
  • Supplier
    • OriGene
    • antibodies-online
    • GenScript
    • ProteoGenix
  • Reactivity
    • Human
    • Mouse
  • Application
    • Protein Expression (PExp)
    • Genome Editing with Engineered Nucleases (GEEN)
    • Cloning (Clon)
    • RNA Interference (RNAi)
  • Conjugate
    • Un-conjugated
    • GFP tag
    • Myc-DYKDDDDK Tag
    • His tag
    • HA tag
    • His-GST
    • His-MBP
    • DYKDDDDK Tag
    • RFP tag
  • Vector Backbone
    • pLenti-U6-sgRNA-PGK-Neo
    • pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
    • pCMV6-Entry
    • pCas-Guide
    • pGFP-C-shLenti
    • pGFP-V-RS
    • pLenti-C-Myc-DDK
    • pLenti-C-mGFP
    • pORF
    • pPB-His-GST
    • pPB-His-MBP
    • pPB-N-His
    • pPM-C-HA
    • pPM-C-His
    • pRS
    • pCMV6-AC-GFP
    • pCMV6-XL4
    • pDONR223
    • pRFP-C-RS
    • pcDNA3.1+C-(K)-DYK
  • Vector
    • Lentiviral Vector
    • Mammalian Expression Vector
    • Bacterial Expression Vector
    • Retroviral Vector
    • Cloning Vector
    • Gateway Cloning Vector
  • Insert
    • cDNA
    • ORF
    • shRNA
    • gRNA + Cas9
    • gRNA
  • Type of Oligonucleotide
    • siRNA Oligo
  • Bacterial Resistance
    • Ampicillin
    • Kanamycin
    • Chloramphenicol
    • Spectinomycin
  • Expression Type
    • Transient
    • Stable
  • Selectable Marker
    • Neomycin
    • Puromycin
  • Promoter
    • U6 Promoter
    • CMV Promoter
    • T7 Promoter
    • Enhanced CMV Promoter
    • PGK Promoter
    • SFFV Promoter
  • Format
    • Lyophilized
    • Liquid
    • Viral Particles

Synonyms and alternative names related to RFWD3

  • ring finger and WD repeat domain 3 (Rfwd3)
  • ring finger and WD repeat domain 3 (RFWD3)
  • BC027246
  • RFWD3
  • RGD1305243
  • RNF201

Gene-IDs for different species

Protein level used designations for RFWD3

  • ring finger and WD repeat domain 3
  • RING finger and WD repeat domain-containing protein 3-like
  • E3 ubiquitin-protein ligase RFWD3
  • RING finger and WD repeat domain-containing protein 3
  • RING finger protein 201
Other products related to RFWD3 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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