RFWD3 (Ring Finger and WD Repeat Domain 3, RFWD3)
Short Description: E3 ubiquitin-protein ligase that mediates the ubiquitination of p53/TP53 in the late response to DNA damage, and acts as a positive regulator of p53/TP53 stability, thereby regulating the G1/S DNA damage checkpoint. May act by catalyzing the formation of short polyubiquitin chains on p53/TP53 that are not targeted to the proteasome. In response to ionizing radiation, interacts with MDM2 and enhances p53/TP53 ubiquitination, possibly by restricting MDM2 from extending polyubiquitin chains on ubiquitinated p53/TP53. Plays a role in RPA-mediated DNA damage signaling and repair.
More information related to gene RFWD3.
More information related to gene RFWD3.
Products related to RFWD3 Gene:
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42 results
OriGene kn514704
gRNA + Cas9
GEEN
Mammalian Expression Vector
pCas-Guide
Ampicillin
U6 Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- gRNA + Cas9
- Application:
- Genome Editing with Engineered Nucleases
- Gene:
- Ring Finger and WD Repeat Domain 3 (RFWD3)
- Species:
- Mouse
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCas-Guide
- Resistance Gene:
- Ampicillin
- Promoter:
- U6 Promoter, Enhanced CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN3225032
$1,640.43
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 21 to 22 Business Days
OriGene kn409196
gRNA + Cas9
GEEN
Mammalian Expression Vector
pCas-Guide
Ampicillin
U6 Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- gRNA + Cas9
- Application:
- Genome Editing with Engineered Nucleases
- Gene:
- Ring Finger and WD Repeat Domain 3 (RFWD3)
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCas-Guide
- Resistance Gene:
- Ampicillin
- Promoter:
- U6 Promoter, Enhanced CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN3225031
$1,640.43
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 21 to 22 Business Days
Synonyms and alternative names related to RFWD3
- ring finger and WD repeat domain 3 (Rfwd3)
- ring finger and WD repeat domain 3 (RFWD3)
- BC027246
- RFWD3
- RGD1305243
- RNF201
Gene-IDs for different species
Protein level used designations for RFWD3
- ring finger and WD repeat domain 3
- RING finger and WD repeat domain-containing protein 3-like
- E3 ubiquitin-protein ligase RFWD3
- RING finger and WD repeat domain-containing protein 3
- RING finger protein 201
Proteomics products related to RFWD3 Gene
Other products related to RFWD3 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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