RIPK1 (Receptor (TNFRSF)-Interacting serine-threonine Kinase 1, RIPK1)
Short Description: Serine-threonine kinase which transduces inflammatory and cell-death signals (necroptosis) following death receptors ligation, activation of pathogen recognition receptors (PRRs), and DNA damage. Upon activation of TNFR1 by the TNF-alpha family cytokines, TRADD and TRAF2 are recruited to the receptor. Ubiquitination by TRAF2 via 'Lys-63'-link chains acts as a critical enhancer of communication with downstream signal transducers in the mitogen-activated protein kinase pathway and the NF-kappa-B pathway, which in turn mediate downstream events including the activation of genes encoding inflammatory molecules. Polyubiquitinated protein binds to IKBKG/NEMO, the regulatory subunit of the IKK complex, a critical event for NF-kappa-B activation. Interaction with other cellular RHIM-containing adapters initiates gene activation and cell death. RIPK1 and RIPK3 association, in particular, forms a necroptosis-inducing complex.
More information related to gene RIPK1.
More information related to gene RIPK1.
Products related to RIPK1 Gene:
Recommended next Filters:
70 results
OriGene sr305755
RNAi
RIPK1
Species: Human
HPLC purified
- Application:
- RNA Interference
- Gene:
- Receptor (TNFRSF)-Interacting serine-threonine Kinase 1
- Species:
- Human
- Purification:
- HPLC purified
Catalog No. ABIN3345519
$512.82
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 4 to 9 Business Days
OriGene mc220144
cDNA
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
Enhanced CMV Promoter
unconjugated
Transient
1
- Type:
- cDNA
- Application:
- Protein Expression
- Gene:
- Receptor (TNFRSF)-Interacting serine-threonine Kinase 1 (RIPK1)
- NCBI Accession:
- NM_009068,NP_033094
- Species:
- Mouse
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-Entry
- Resistance Gene:
- Kanamycin
- Selection Marker:
- Neomycin
- Promoter:
- Enhanced CMV Promoter
- Expression:
- Transient
Catalog No. ABIN3368072
$605.88
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 4 to 9 Business Days
OriGene rc216024
ORF
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
CMV Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Receptor (TNFRSF)-Interacting serine-threonine Kinase 1 (RIPK1)
- NCBI Accession:
- NM_003804,NP_003795
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-Entry
- Resistance Gene:
- Kanamycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN5456707
$607.86
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 8 to 11 Business Days
OriGene sc323466
cDNA
PExp
Mammalian Expression Vector
pCMV6-XL5
Ampicillin
Enhanced CMV Promoter
unconjugated
Transient
1
- Type:
- cDNA
- Application:
- Protein Expression
- Gene:
- Receptor (TNFRSF)-Interacting serine-threonine Kinase 1 (RIPK1)
- NCBI Accession:
- NM_003804,NP_003795
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-XL5
- Resistance Gene:
- Ampicillin
- Promoter:
- Enhanced CMV Promoter, T7 Promoter
- Expression:
- Transient
Catalog No. ABIN3391905
$608.85
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 4 to 9 Business Days
OriGene sc108466
cDNA
PExp
Mammalian Expression Vector
pCMV6-XL5
Ampicillin
Enhanced CMV Promoter
unconjugated
Transient
1
2
- Type:
- cDNA
- Application:
- Protein Expression
- Gene:
- Receptor (TNFRSF)-Interacting serine-threonine Kinase 1 (RIPK1)
- NCBI Accession:
- NM_003804,NP_003795
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-XL5
- Resistance Gene:
- Ampicillin
- Promoter:
- Enhanced CMV Promoter, T7 Promoter
- Expression:
- Transient
Catalog No. ABIN3386381
$608.85
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 4 to 9 Business Days
OriGene rr212430
ORF
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
CMV Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Receptor (TNFRSF)-Interacting serine-threonine Kinase 1 (RIPK1)
- NCBI Accession:
- NM_001107350,NP_001100820
- Species:
- Rat
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-Entry
- Resistance Gene:
- Kanamycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN5456708
$667.26
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 21 to 22 Business Days
OriGene rn212430
cDNA
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
Enhanced CMV Promoter
unconjugated
Transient
1
- Type:
- cDNA
- Application:
- Protein Expression
- Gene:
- Receptor (TNFRSF)-Interacting serine-threonine Kinase 1 (RIPK1)
- NCBI Accession:
- NM_001107350,NP_001100820
- Species:
- Rat
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-Entry
- Resistance Gene:
- Kanamycin
- Selection Marker:
- Neomycin
- Promoter:
- Enhanced CMV Promoter
- Expression:
- Transient
Catalog No. ABIN3368073
$668.25
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 21 to 22 Business Days
OriGene tg501905
shRNA
RNAi
Retroviral Vector
pGFP-V-RS
Kanamycin
U6 Promoter
GFP tag
Transient
1
- Type:
- shRNA
- Application:
- RNA Interference
- Gene:
- Receptor (TNFRSF)-Interacting serine-threonine Kinase 1 (RIPK1)
- Species:
- Mouse
- Vector type:
- Retroviral Vector
- Vector backbone:
- pGFP-V-RS
- Resistance Gene:
- Kanamycin
- Selection Marker:
- Puromycin
- Promoter:
- U6 Promoter
- Fusion Tag:
- GFP tag
- Expression:
- Transient, Stable
Catalog No. ABIN3683946
$707.85
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 16 to 17 Business Days
OriGene tg320591
shRNA
RNAi
Retroviral Vector
pGFP-V-RS
Kanamycin
U6 Promoter
GFP tag
Transient
1
2
- Type:
- shRNA
- Application:
- RNA Interference
- Gene:
- Receptor (TNFRSF)-Interacting serine-threonine Kinase 1 (RIPK1)
- Species:
- Human
- Vector type:
- Retroviral Vector
- Vector backbone:
- pGFP-V-RS
- Resistance Gene:
- Kanamycin
- Selection Marker:
- Puromycin
- Promoter:
- U6 Promoter
- Fusion Tag:
- GFP tag
- Expression:
- Transient, Stable
Catalog No. ABIN3744380
$707.85
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 16 to 17 Business Days
OriGene tf705914
shRNA
RNAi
Retroviral Vector
pRFP-C-RS
Chloramphenicol
U6 Promoter
RFP tag
Transient
1
- Type:
- shRNA
- Application:
- RNA Interference
- Gene:
- Receptor (TNFRSF)-Interacting serine-threonine Kinase 1 (RIPK1)
- Species:
- Rat
- Vector type:
- Retroviral Vector
- Vector backbone:
- pRFP-C-RS
- Resistance Gene:
- Chloramphenicol
- Selection Marker:
- Puromycin
- Promoter:
- U6 Promoter
- Fusion Tag:
- RFP tag
- Expression:
- Transient, Stable
Catalog No. ABIN3486204
$707.85
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 16 to 17 Business Days
Synonyms and alternative names related to RIPK1
- receptor interacting serine/threonine kinase 1 (RIPK1)
- receptor (TNFRSF)-interacting serine-threonine kinase 1 (Ripk1)
- receptor interacting serine/threonine kinase 1 (Ripk1)
- receptor interacting serine/threonine kinase 1 L homeolog (ripk1.L)
- D330015H01Rik
- Rinp
- RIP
- RIP1
- Rip1
- rip1
- ripk1
- xrip1
- xRIP1beta
Gene-IDs for different species
Protein level used designations for RIPK1
- RIP-1
- cell death protein RIP
- receptor interacting protein
- receptor-interacting protein 1
- receptor-interacting serine/threonine-protein kinase 1
- serine/threonine-protein kinase RIP
- receptor (TNFRSF)-interacting serine-threonine kinase 1
- receptor interacting serine/threonine kinase 1 L homeolog
- receptor-interacting protein 1 beta
Proteomics products related to RIPK1 Gene
Other products related to RIPK1 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
You are here:
