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SCN8A (Sodium Channel, Voltage-Gated, Type VIII, alpha, SCN8A)

Short Description: This gene encodes a member of the sodium channel alpha subunit gene family. The encoded protein forms the ion pore region of the voltage-gated sodium channel. This protein is essential for the rapid membrane depolarization that occurs during the formation of the action potential in excitable neurons. Mutations in this gene are associated with mental retardation, pancerebellar atrophy and ataxia. Alternate splicing results in multiple transcript variants.[provided by RefSeq, May 2010].
More information related to gene SCN8A.

Products related to SCN8A Gene:

56 results

OriGene kn423887 gRNA + Cas9 GEEN Mammalian Expression Vector pCas-Guide Ampicillin U6 Promoter Myc-DYKDDDDK Tag Transient
Type:
gRNA + Cas9
Application:
Genome Editing with Engineered Nucleases
Gene:
Sodium Channel, Voltage-Gated, Type VIII, alpha (SCN8A)
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pCas-Guide
Resistance Gene:
Ampicillin
Promoter:
U6 Promoter, Enhanced CMV Promoter
Fusion Tag:
Myc-DYKDDDDK Tag
Expression:
Transient
Catalog No. ABIN3226406
$1,640.43
Plus shipping costs $50.00
1 kit
Shipping to: United States
Delivery in 21 to 22 Business Days
OriGene kn515390 gRNA + Cas9 GEEN Mammalian Expression Vector pCas-Guide Ampicillin U6 Promoter Myc-DYKDDDDK Tag Transient
Type:
gRNA + Cas9
Application:
Genome Editing with Engineered Nucleases
Gene:
Sodium Channel, Voltage-Gated, Type VIII, alpha (SCN8A)
Species:
Mouse
Vector type:
Mammalian Expression Vector
Vector backbone:
pCas-Guide
Resistance Gene:
Ampicillin
Promoter:
U6 Promoter, Enhanced CMV Promoter
Fusion Tag:
Myc-DYKDDDDK Tag
Expression:
Transient
Catalog No. ABIN3226407
$1,640.43
Plus shipping costs $50.00
1 kit
Shipping to: United States
Delivery in 21 to 22 Business Days
OriGene sr423338 RNAi SCN8A Species: Mouse HPLC purified
Application:
RNA Interference
Gene:
Sodium Channel, Voltage-Gated, Type VIII, alpha
Species:
Mouse
Purification:
HPLC purified
Catalog No. ABIN3350182
$512.82
Plus shipping costs $50.00
1 kit
Shipping to: United States
Delivery in 16 to 17 Business Days
OriGene sr511660 RNAi SCN8A Species: Rat HPLC purified
Application:
RNA Interference
Gene:
Sodium Channel, Voltage-Gated, Type VIII, alpha
Species:
Rat
Purification:
HPLC purified
Catalog No. ABIN3360547
$512.82
Plus shipping costs $50.00
1 kit
Shipping to: United States
Delivery in 16 to 17 Business Days
OriGene rn211948 cDNA PExp Mammalian Expression Vector pCMV6-Entry Kanamycin Enhanced CMV Promoter unconjugated Transient
Type:
cDNA
Application:
Protein Expression
Gene:
Sodium Channel, Voltage-Gated, Type VIII, alpha (SCN8A)
NCBI Accession:
NM_019266,NP_062139
Species:
Rat
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-Entry
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
Enhanced CMV Promoter
Expression:
Transient
Catalog No. ABIN3369270
$2,633.40
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 41 to 42 Business Days
OriGene sc304060 cDNA PExp Mammalian Expression Vector pCMV6-XL4 Ampicillin Enhanced CMV Promoter unconjugated Transient
Pubmed 1
Type:
cDNA
Application:
Protein Expression
Gene:
Sodium Channel, Voltage-Gated, Type VIII, alpha (SCN8A)
NCBI Accession:
NM_014191,NP_055006
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-XL4
Resistance Gene:
Ampicillin
Promoter:
Enhanced CMV Promoter, T7 Promoter
Expression:
Transient
Catalog No. ABIN3381762
$2,472.03
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 21 to 22 Business Days
OriGene sc329376 cDNA PExp Mammalian Expression Vector pCMV6-XL5 Ampicillin Enhanced CMV Promoter unconjugated Transient
Type:
cDNA
Application:
Protein Expression
Gene:
Sodium Channel, Voltage-Gated, Type VIII, alpha (SCN8A)
NCBI Accession:
NM_001177984,NP_001171455
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-XL5
Resistance Gene:
Ampicillin
Promoter:
Enhanced CMV Promoter, T7 Promoter
Expression:
Transient
Catalog No. ABIN3392075
$1,775.07
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 41 to 42 Business Days
ORF PExp Mammalian Expression Vector pcDNA3.1+C-(K)-DYK Ampicillin CMV Promoter DYKDDDDK Tag Transient
ISO 9001:2008
Type:
ORF
Application:
Protein Expression
Gene:
Sodium Channel, Voltage-Gated, Type VIII, alpha (SCN8A)
NCBI Accession:
NM_014191
Gene ID:
6334 (Human, SCN8A)
Vector type:
Mammalian Expression Vector
Vector backbone:
pcDNA3.1+C-(K)-DYK
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
DYKDDDDK Tag
Expression:
Transient, Stable
Catalog No. ABIN4946339
$1,319.00
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 2 to 5 Business Days
ORF PExp Mammalian Expression Vector pcDNA3.1+C-(K)-DYK Ampicillin CMV Promoter DYKDDDDK Tag Transient
ISO 9001:2008
Type:
ORF
Application:
Protein Expression
Gene:
Sodium Channel, Voltage-Gated, Type VIII, alpha (SCN8A)
NCBI Accession:
NM_001177984
Gene ID:
6334 (Human, SCN8A)
Vector type:
Mammalian Expression Vector
Vector backbone:
pcDNA3.1+C-(K)-DYK
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
DYKDDDDK Tag
Expression:
Transient, Stable
Catalog No. ABIN4946567
$1,319.00
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 26 to 27 Business Days
OriGene rc223887 ORF PExp Mammalian Expression Vector pCMV6-AC-Myc-DDK Ampicillin CMV Promoter Myc-DYKDDDDK Tag Stable
Type:
ORF
Application:
Protein Expression
Gene:
Sodium Channel, Voltage-Gated, Type VIII, alpha (SCN8A)
NCBI Accession:
NM_014191,NP_055006
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-AC-Myc-DDK
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
Myc-DYKDDDDK Tag
Expression:
Stable, Transient
Catalog No. ABIN5457394
$1,647.36
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 8 to 11 Business Days
  • Type
    • Plasmid
    • Primer
  • Supplier
    • antibodies-online
    • OriGene
    • GenScript
  • Reactivity
    • Mouse
    • Human
    • Rat
  • Cited in publications
  • Application
    • Protein Expression (PExp)
    • Genome Editing with Engineered Nucleases (GEEN)
    • Cloning (Clon)
    • RNA Interference (RNAi)
  • Conjugate
    • Un-conjugated
    • GFP tag
    • Myc-DYKDDDDK Tag
    • His tag
    • HA tag
    • His-GST
    • His-MBP
    • DYKDDDDK Tag
  • Vector Backbone
    • pLenti-U6-sgRNA-PGK-Neo
    • pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
    • pCMV6-Entry
    • pGFP-C-shLenti
    • pGFP-V-RS
    • pORF
    • pPB-His-GST
    • pPB-His-MBP
    • pPB-N-His
    • pPM-C-HA
    • pPM-C-His
    • pRS
    • pCMV6-AC-GFP
    • pCas-Guide
    • pLenti-C-Myc-DDK
    • pcDNA3.1+C-(K)-DYK
    • pCMV6-AC-Myc-DDK
    • pCMV6-XL4
    • pCMV6-XL5
  • Vector
    • Mammalian Expression Vector
    • Lentiviral Vector
    • Bacterial Expression Vector
    • Retroviral Vector
    • Cloning Vector
  • Insert
    • cDNA
    • ORF
    • shRNA
    • gRNA + Cas9
    • gRNA
  • Type of Oligonucleotide
    • siRNA Oligo
  • Bacterial Resistance
    • Ampicillin
    • Kanamycin
    • Chloramphenicol
    • Spectinomycin
  • Expression Type
    • Transient
    • Stable
  • Selectable Marker
    • Neomycin
    • Puromycin
  • Promoter
    • U6 Promoter
    • CMV Promoter
    • T7 Promoter
    • PGK Promoter
    • SFFV Promoter
    • Enhanced CMV Promoter
  • Format
    • Lyophilized
    • Liquid
    • Viral Particles

Synonyms and alternative names related to SCN8A

  • sodium voltage-gated channel alpha subunit 8 (SCN8A)
  • sodium voltage-gated channel alpha subunit 8 (Scn8a)
  • sodium channel, voltage-gated, type VIII, alpha (Scn8a)
  • AI853486
  • C630029C19Rik
  • CERIII
  • CIAT
  • dmu
  • EIEE13
  • MED
  • med
  • mnd-2
  • mnd2
  • NaCh6
  • Nav1.6
  • nmf2
  • nmf58
  • nmf335
  • nur14
  • PN4
  • seal

Gene-IDs for different species

Protein level used designations for SCN8A

  • hNa6/Scn8a voltage-gated sodium channel
  • sodium channel protein type 8 subunit alpha
  • voltage-gated sodium channel subunit alpha Nav1.6
  • Na+ channel
  • PN4
  • naCh6
  • peripheral nerve protein type 4
  • sodium channel 6
  • sodium channel protein type VIII subunit alpha
  • sodium channel voltage-gated type VIII alpha polypeptide
  • sodium channel, voltage-gated, type 8, alpha polypeptide
  • sodium channel, voltage-gated, type 8, alpha subunit
  • sodium channel, voltage-gated, type VIII, alpha polypeptide
  • ataxia 3
Other products related to SCN8A such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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