SMAD4 (SMAD Family Member 4, SMAD4)
Short Description: This gene encodes a member of the Smad family of signal transduction proteins. Smad proteins are phosphorylated and activated by transmembrane serine-threonine receptor kinases in response to TGF-beta signaling. The product of this gene forms homomeric complexes and heteromeric complexes with other activated Smad proteins, which then accumulate in the nucleus and regulate the transcription of target genes. This protein binds to DNA and recognizes an 8-bp palindromic sequence (GTCTAGAC) called the Smad-binding element (SBE). The Smad proteins are subject to complex regulation by post-translational modifications. Mutations or deletions in this gene have been shown to result in pancreatic cancer, juvenile polyposis syndrome, and hereditary hemorrhagic telangiectasia syndrome. [provided by RefSeq, Oct 2009].
More information related to gene SMAD4.
More information related to gene SMAD4.
Products related to SMAD4 Gene:
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57 results
OriGene tl710284
shRNA
RNAi
Lentiviral Vector
pGFP-C-shLenti
Chloramphenicol
U6 Promoter
GFP tag
Transient
1
- Type:
- shRNA
- Application:
- RNA Interference
- Gene:
- SMAD Family Member 4 (SMAD4)
- Species:
- Rat
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pGFP-C-shLenti
- Resistance Gene:
- Chloramphenicol
- Selection Marker:
- Puromycin
- Promoter:
- U6 Promoter
- Fusion Tag:
- GFP tag
- Expression:
- Transient, Stable
Catalog No. ABIN3447565
$1,002.87
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 16 to 17 Business Days
OriGene tr501287
shRNA
RNAi
Retroviral Vector
pRS
Ampicillin
U6 Promoter
unconjugated
Transient
1
- Type:
- shRNA
- Application:
- RNA Interference
- Gene:
- SMAD Family Member 4 (SMAD4)
- Species:
- Mouse
- Vector type:
- Retroviral Vector
- Vector backbone:
- pRS
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Puromycin
- Promoter:
- U6 Promoter
- Expression:
- Transient, Stable
Catalog No. ABIN3533631
$874.17
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 4 to 9 Business Days
OriGene tr710284
shRNA
RNAi
Retroviral Vector
pRS
Ampicillin
U6 Promoter
unconjugated
Transient
1
- Type:
- shRNA
- Application:
- RNA Interference
- Gene:
- SMAD Family Member 4 (SMAD4)
- Species:
- Rat
- Vector type:
- Retroviral Vector
- Vector backbone:
- pRS
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Puromycin
- Promoter:
- U6 Promoter
- Expression:
- Transient, Stable
Catalog No. ABIN3435174
$874.17
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 16 to 17 Business Days
OriGene tg710284
shRNA
RNAi
Retroviral Vector
pGFP-V-RS
Kanamycin
U6 Promoter
GFP tag
Transient
1
- Type:
- shRNA
- Application:
- RNA Interference
- Gene:
- SMAD Family Member 4 (SMAD4)
- Species:
- Rat
- Vector type:
- Retroviral Vector
- Vector backbone:
- pGFP-V-RS
- Resistance Gene:
- Kanamycin
- Selection Marker:
- Puromycin
- Promoter:
- U6 Promoter
- Fusion Tag:
- GFP tag
- Expression:
- Transient, Stable
Catalog No. ABIN3504492
$707.85
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 16 to 17 Business Days
OriGene sr417200
RNAi
SMAD4
Species: Mouse
HPLC purified
- Application:
- RNA Interference
- Gene:
- SMAD Family Member 4
- Species:
- Mouse
- Purification:
- HPLC purified
Catalog No. ABIN3264735
$512.82
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 4 to 9 Business Days
OriGene sr505632
RNAi
SMAD4
Species: Rat
HPLC purified
- Application:
- RNA Interference
- Gene:
- SMAD Family Member 4
- Species:
- Rat
- Purification:
- HPLC purified
Catalog No. ABIN3355374
$512.82
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 16 to 17 Business Days
OriGene kn316273
gRNA + Cas9
GEEN
Mammalian Expression Vector
pCas-Guide
Ampicillin
U6 Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- gRNA + Cas9
- Application:
- Genome Editing with Engineered Nucleases
- Gene:
- SMAD Family Member 4 (SMAD4)
- Species:
- Mouse
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCas-Guide
- Resistance Gene:
- Ampicillin
- Promoter:
- U6 Promoter, Enhanced CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN3223826
$1,640.43
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 21 to 22 Business Days
OriGene kn201828
gRNA + Cas9
GEEN
Mammalian Expression Vector
pCas-Guide
Ampicillin
U6 Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- gRNA + Cas9
- Application:
- Genome Editing with Engineered Nucleases
- Gene:
- SMAD Family Member 4 (SMAD4)
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCas-Guide
- Resistance Gene:
- Ampicillin
- Promoter:
- U6 Promoter, Enhanced CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN3223825
$1,640.43
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 21 to 22 Business Days
OriGene rn205918
cDNA
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
Enhanced CMV Promoter
unconjugated
Transient
1
- Type:
- cDNA
- Application:
- Protein Expression
- Gene:
- SMAD Family Member 4 (SMAD4)
- NCBI Accession:
- NM_019275,NP_062148
- Species:
- Rat
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-Entry
- Resistance Gene:
- Kanamycin
- Selection Marker:
- Neomycin
- Promoter:
- Enhanced CMV Promoter
- Expression:
- Transient
Catalog No. ABIN3371184
$764.28
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 21 to 22 Business Days
OriGene mc218774
cDNA
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
Enhanced CMV Promoter
unconjugated
Transient
1
- Type:
- cDNA
- Application:
- Protein Expression
- Gene:
- SMAD Family Member 4 (SMAD4)
- NCBI Accession:
- NM_008540,NP_032566
- Species:
- Mouse
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-Entry
- Resistance Gene:
- Kanamycin
- Selection Marker:
- Neomycin
- Promoter:
- Enhanced CMV Promoter
- Expression:
- Transient
Catalog No. ABIN3371183
$508.86
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 4 to 9 Business Days
Synonyms and alternative names related to SMAD4
- SMAD family member 4 (SMAD4)
- Smad4 protein (smad4)
- SMAD family member 4 (Smad4)
- SMAD family member 4, gene 1 L homeolog (smad4.1.L)
- AW743858
- D18Wsu70e
- DPC4
- dpc4
- JIP
- jip
- MADH4
- Madh4
- madh4
- MYHRS
- smad4
- Xsmad4
- xsmad4a
- XSmad4alpha
Gene-IDs for different species
Protein level used designations for SMAD4
- Mothers against decapentaplegic-like protein 4
- mothers against decapentaplegic homolog 4
- Smad4 protein
- SMAD family member 4
- mothers against decapentaplegic homolog 4-like
- MAD homolog 4
- SMAD, mothers against DPP homolog 4
- deleted in pancreatic carcinoma locus 4
- deletion target in pancreatic carcinoma 4
- mothers against decapentaplegic, Drosophila, homolog of, 4
- Smad 4
- deletion target in pancreatic carcinoma 4 homolog
- mothers against DPP homolog 4
- MAD (mothers against decapentaplegic Drosophila) homolog 4
- SMAD 4
- MAD, mothers against decapentaplegic homolog 4
- mothers against DPP-like 4
- mothers against decapentaplegic-like 4
Proteomics products related to SMAD4 Gene
Other products related to SMAD4 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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