TCR beta (T Cell Receptor (TCR) beta, TCR beta)
Short Description: T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface of antigen presenting cells (APC). Each T cell receptor is a dimer consisting of one alpha and one beta chain or one delta and one gamma chain. In a single cell, the T cell receptor loci are rearranged and expressed in the order delta, gamma, beta, and alpha. If both delta and gamma rearrangements produce functional chains, the cell expresses delta and gamma. If not, the cell proceeds to rearrange the beta and alpha loci. This region represents the germline organization of the T cell receptor beta locus. The beta locus includes V (variable), J (joining), diversity (D), and C (constant) segments. During T cell development, the beta chain is synthesized by a recombination event at the DNA level joining a D segment with a J segment; a V segment is then joined to the D-J gene. The C segment is later joined by splicing at the RNA level. Recombination of many different V segments with several J segments provides a wide range of antigen recognition. Additional diversity is attained by junctional diversity, resulting from the random additional of nucleotides by terminal deoxynucleotidyltransferase. Several V segments of the beta locus are known to be incapable of encoding a protein and are considered pseudogenes. The beta locus also includes several trypsinogen genes. [provided by RefSeq, Jul 2008]
More information related to gene TCR beta.
More information related to gene TCR beta.
Products related to TCR beta Gene:
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OriGene mc218668
cDNA
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
Enhanced CMV Promoter
unconjugated
Transient
1
- Type:
- cDNA
- Application:
- Protein Expression
- Gene:
- T Cell Receptor (TCR) beta (TCR beta)
- Species:
- Mouse
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-Entry
- Resistance Gene:
- Kanamycin
- Selection Marker:
- Neomycin
- Promoter:
- Enhanced CMV Promoter
- Expression:
- Transient
Catalog No. ABIN3335893
$163.35
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 21 to 22 Business Days
OriGene mc218669
cDNA
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
Enhanced CMV Promoter
unconjugated
Transient
1
- Type:
- cDNA
- Application:
- Protein Expression
- Gene:
- T Cell Receptor (TCR) beta (TCR beta)
- Species:
- Mouse
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-Entry
- Resistance Gene:
- Kanamycin
- Selection Marker:
- Neomycin
- Promoter:
- Enhanced CMV Promoter
- Expression:
- Transient
Catalog No. ABIN3335894
$326.70
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 21 to 22 Business Days
Synonyms and alternative names related to TCR beta
- T cell receptor beta chain (Tcrb)
- T-cell receptor beta chain (Tcrb)
- T cell receptor beta variable 20/OR9-2 (non-functional) (TRBV20OR9-2)
- CDR3
- RATTCB
- RATTCBC1
- TCB
- TCBC1
- TCR
- TCRB
- TCRbeta
- TCRBV2O
- TCRBV2S2O
- TCRBV20S2
- Tib
- TRB
Gene-IDs for different species
Protein level used designations for TCR beta
- T-cell receptor beta chain
- T-cell receptor beta cluster
- variable region-beta 8.5
- T cell receptor beta variable 20/OR9-2 pseudogene
- T-cell receptor beta chain variable region
- T-cell receptor, beta variable region 2, orphon
- TRBV20/OR9-2
Proteomics products related to TCR beta Gene
Other products related to TCR beta such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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