TRAF6 (TNF Receptor-Associated Factor 6, TRAF6)
Short Description: The protein encoded by this gene is a member of the TNF receptor associated factor (TRAF) protein family. TRAF proteins are associated with, and mediate signal transduction from, members of the TNF receptor superfamily. This protein mediates signaling from members of the TNF receptor superfamily as well as the Toll/IL-1 family. Signals from receptors such as CD40, TNFSF11/RANCE and IL-1 have been shown to be mediated by this protein. This protein also interacts with various protein kinases including IRAK1/IRAK, SRC and PKCzeta, which provides a link between distinct signaling pathways. This protein functions as a signal transducer in the NF-kappaB pathway that activates IkappaB kinase (IKK) in response to proinflammatory cytokines. The interaction of this protein with UBE2N/UBC13, and UBE2V1/UEV1A, which are ubiquitin conjugating enzymes catalyzing the formation of polyubiquitin chains, has been found to be required for IKK activation by this protein. This protein also interacts with the transforming growth factor (TGF) beta receptor complex and is required for Smad-independent activation of the JNK and p38 kinases. This protein has an amino terminal RING domain which is followed by four zinc-finger motifs, a central coiled-coil region and a highly conserved carboxyl terminal domain, known as the TRAF-C domain. Two alternatively spliced transcript variants, encoding an identical protein, have been reported. [provided by RefSeq, Feb 2012].
More information related to gene TRAF6.
More information related to gene TRAF6.
Products related to TRAF6 Gene:
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64 results
ORF
Clon
Gateway Cloning Vector
pDONR223
Spectinomycin
unconjugated
Catalog No. ABIN5322681
$223.79
Plus shipping costs $50.00
2 μg
Shipping to:
United States
Delivery in 15 to 17 Business Days
ORF
PExp
Mammalian Expression Vector
pcDNA3.1+C-(K)-DYK
Ampicillin
CMV Promoter
DYKDDDDK Tag
Transient
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- TNF Receptor-Associated Factor 6 (TRAF6)
- NCBI Accession:
- NM_004620
- Gene ID:
- 7189 (Human, TRAF6)
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pcDNA3.1+C-(K)-DYK
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Neomycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- DYKDDDDK Tag
- Expression:
- Transient, Stable
Catalog No. ABIN4917675
$379.00
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 4 to 6 Business Days
OriGene rc219528
ORF
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
CMV Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- TNF Receptor-Associated Factor 6 (TRAF6)
- NCBI Accession:
- NM_004620,NP_004611
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-Entry
- Resistance Gene:
- Kanamycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN5407392
$481.14
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 8 to 10 Business Days
OriGene sc109844
cDNA
PExp
Mammalian Expression Vector
pCMV6-XL4
Ampicillin
Enhanced CMV Promoter
unconjugated
Transient
1
1
- Type:
- cDNA
- Application:
- Protein Expression
- Gene:
- TNF Receptor-Associated Factor 6 (TRAF6)
- NCBI Accession:
- NM_004620,NP_004611
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-XL4
- Resistance Gene:
- Ampicillin
- Promoter:
- Enhanced CMV Promoter, T7 Promoter
- Expression:
- Transient
Catalog No. ABIN3380442
$482.13
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 4 to 8 Business Days
OriGene sr510754
RNAi
TRAF6
Species: Rat
HPLC purified
- Application:
- RNA Interference
- Gene:
- TNF Receptor-Associated Factor 6
- Species:
- Rat
- Purification:
- HPLC purified
Catalog No. ABIN3359757
$512.82
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Will be delivered in 16 Business Days
OriGene rr211042
ORF
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
CMV Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- TNF Receptor-Associated Factor 6 (TRAF6)
- NCBI Accession:
- NM_001107754,NP_001101224
- Species:
- Rat
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-Entry
- Resistance Gene:
- Kanamycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN5407393
$537.57
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Will be delivered in 21 Business Days
OriGene mc217548
cDNA
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
Enhanced CMV Promoter
unconjugated
Transient
1
- Type:
- cDNA
- Application:
- Protein Expression
- Gene:
- TNF Receptor-Associated Factor 6 (TRAF6)
- NCBI Accession:
- NM_009424,NP_033450
- Species:
- Mouse
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-Entry
- Resistance Gene:
- Kanamycin
- Selection Marker:
- Neomycin
- Promoter:
- Enhanced CMV Promoter
- Expression:
- Transient
Catalog No. ABIN3337531
$538.56
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Will be delivered in 21 Business Days
OriGene rn211042
cDNA
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
Enhanced CMV Promoter
unconjugated
Transient
1
- Type:
- cDNA
- Application:
- Protein Expression
- Gene:
- TNF Receptor-Associated Factor 6 (TRAF6)
- NCBI Accession:
- NM_001107754,NP_001101224
- Species:
- Rat
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-Entry
- Resistance Gene:
- Kanamycin
- Selection Marker:
- Neomycin
- Promoter:
- Enhanced CMV Promoter
- Expression:
- Transient
Catalog No. ABIN3337533
$538.56
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Will be delivered in 21 Business Days
OriGene mc228188
cDNA
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
Enhanced CMV Promoter
unconjugated
Transient
1
- Type:
- cDNA
- Application:
- Protein Expression
- Gene:
- TNF Receptor-Associated Factor 6 (TRAF6)
- NCBI Accession:
- NM_001303273,NP_001290202
- Species:
- Mouse
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-Entry
- Resistance Gene:
- Kanamycin
- Selection Marker:
- Neomycin
- Promoter:
- Enhanced CMV Promoter
- Expression:
- Transient
Catalog No. ABIN3337532
$538.56
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Will be delivered in 21 Business Days
OriGene rg219528
ORF
PExp
Mammalian Expression Vector
pCMV6-AC-GFP
Ampicillin
CMV Promoter
GFP tag
Stable
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- TNF Receptor-Associated Factor 6 (TRAF6)
- NCBI Accession:
- NM_004620,NP_004611
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-AC-GFP
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Neomycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- GFP tag
- Expression:
- Stable, Transient
Catalog No. ABIN5407390
$679.14
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Will be delivered in 21 Business Days
Synonyms and alternative names related to TRAF6
- TNF receptor associated factor 6 (TRAF6)
- TNF receptor-associated factor 6 (Traf6)
- TNF receptor associated factor 6 L homeolog (traf6.L)
- TNF-receptor-associated factor 6 (Traf6)
- TNF receptor associated factor 6 (Traf6)
- TNF receptor associated factor 6 (traf6)
- TNF receptor-associated factor 6 (LOC551819)
- TNF receptor-associated factor 6 (traf6)
- TNF receptor associated factor 6 S homeolog (traf6.S)
- 2310003F17Rik
- AI851288
- C630032O20Rik
- CG10961
- Dmel\\CG10961
- DTRAF2
- dTRAF2
- dTraf2
- dtraf2
- dTRAF6
- fi15f02
- GB10539
- MGC:3310
- RNF85
- rnf85
- TRAF
- TRAF2
- Traf2
- traf6
- TRAF6
- wu:fi15f02
- xtraf6
- zgc:63704
Gene-IDs for different species
Protein level used designations for TRAF6
- E3 ubiquitin-protein ligase TRAF6
- RING finger protein 85
- TNF receptor-associated factor 6
- interleukin-1 signal transducer
- TNF receptor-associated factor 6-B
- CG10961-PA
- TNF-receptor-associated factor 2
- Traf6-PA
- TNF-receptor associated factor 6
- TNF receptor-associated factor 6-like
- TNF receptor-associated factor 6-A
- TNF receptor-associated factor 6, E3 ubiquitin protein ligase
Proteomics products related to TRAF6 Gene
Other products related to TRAF6 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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