TRAF6 (TNF Receptor-Associated Factor 6, TRAF6)
Short Description: The protein encoded by this gene is a member of the TNF receptor associated factor (TRAF) protein family. TRAF proteins are associated with, and mediate signal transduction from, members of the TNF receptor superfamily. This protein mediates signaling from members of the TNF receptor superfamily as well as the Toll/IL-1 family. Signals from receptors such as CD40, TNFSF11/RANCE and IL-1 have been shown to be mediated by this protein. This protein also interacts with various protein kinases including IRAK1/IRAK, SRC and PKCzeta, which provides a link between distinct signaling pathways. This protein functions as a signal transducer in the NF-kappaB pathway that activates IkappaB kinase (IKK) in response to proinflammatory cytokines. The interaction of this protein with UBE2N/UBC13, and UBE2V1/UEV1A, which are ubiquitin conjugating enzymes catalyzing the formation of polyubiquitin chains, has been found to be required for IKK activation by this protein. This protein also interacts with the transforming growth factor (TGF) beta receptor complex and is required for Smad-independent activation of the JNK and p38 kinases. This protein has an amino terminal RING domain which is followed by four zinc-finger motifs, a central coiled-coil region and a highly conserved carboxyl terminal domain, known as the TRAF-C domain. Two alternatively spliced transcript variants, encoding an identical protein, have been reported. [provided by RefSeq, Feb 2012].
More information related to gene TRAF6.
More information related to gene TRAF6.
Products related to TRAF6 Gene:
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64 results
OriGene rc206042l2v
ORF
PExp
Lentiviral Vector
pLenti-C-mGFP
Chloramphenicol
CMV Promoter
GFP tag
Transient
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- TNF Receptor-Associated Factor 6 (TRAF6)
- Species:
- Human
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-C-mGFP
- Resistance Gene:
- Chloramphenicol
- Promoter:
- CMV Promoter
- Fusion Tag:
- GFP tag
- Expression:
- Transient
Catalog No. ABIN6402276
$1,266.21
Plus shipping costs $50.00, if applicable $20.00 dry ice
200 μL
Shipping to:
United States
Delivery in 21 to 26 Business Days
OriGene rc206042l1v
ORF
PExp
Lentiviral Vector
pLenti-C-Myc-DDK
Chloramphenicol
CMV Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- TNF Receptor-Associated Factor 6 (TRAF6)
- Species:
- Human
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-C-Myc-DDK
- Resistance Gene:
- Chloramphenicol
- Promoter:
- CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN6402275
$1,266.21
Plus shipping costs $50.00, if applicable $20.00 dry ice
200 μL
Shipping to:
United States
Delivery in 21 to 26 Business Days
OriGene kn518129
gRNA + Cas9
GEEN
Mammalian Expression Vector
pCas-Guide
Ampicillin
U6 Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- gRNA + Cas9
- Application:
- Genome Editing with Engineered Nucleases
- Gene:
- TNF Receptor-Associated Factor 6 (TRAF6)
- Species:
- Mouse
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCas-Guide
- Resistance Gene:
- Ampicillin
- Promoter:
- U6 Promoter, Enhanced CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN3258501
$1,640.43
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Will be delivered in 21 Business Days
OriGene kn206042
gRNA + Cas9
GEEN
Mammalian Expression Vector
pCas-Guide
Ampicillin
U6 Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- gRNA + Cas9
- Application:
- Genome Editing with Engineered Nucleases
- Gene:
- TNF Receptor-Associated Factor 6 (TRAF6)
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCas-Guide
- Resistance Gene:
- Ampicillin
- Promoter:
- U6 Promoter, Enhanced CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN3258500
$1,640.43
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Will be delivered in 21 Business Days
Synonyms and alternative names related to TRAF6
- TNF receptor associated factor 6 (TRAF6)
- TNF receptor-associated factor 6 (Traf6)
- TNF receptor associated factor 6 L homeolog (traf6.L)
- TNF-receptor-associated factor 6 (Traf6)
- TNF receptor associated factor 6 (Traf6)
- TNF receptor associated factor 6 (traf6)
- TNF receptor-associated factor 6 (LOC551819)
- TNF receptor-associated factor 6 (traf6)
- TNF receptor associated factor 6 S homeolog (traf6.S)
- 2310003F17Rik
- AI851288
- C630032O20Rik
- CG10961
- Dmel\\CG10961
- DTRAF2
- dTRAF2
- dTraf2
- dtraf2
- dTRAF6
- fi15f02
- GB10539
- MGC:3310
- RNF85
- rnf85
- TRAF
- TRAF2
- Traf2
- traf6
- TRAF6
- wu:fi15f02
- xtraf6
- zgc:63704
Gene-IDs for different species
Protein level used designations for TRAF6
- E3 ubiquitin-protein ligase TRAF6
- RING finger protein 85
- TNF receptor-associated factor 6
- interleukin-1 signal transducer
- TNF receptor-associated factor 6-B
- CG10961-PA
- TNF-receptor-associated factor 2
- Traf6-PA
- TNF-receptor associated factor 6
- TNF receptor-associated factor 6-like
- TNF receptor-associated factor 6-A
- TNF receptor-associated factor 6, E3 ubiquitin protein ligase
Proteomics products related to TRAF6 Gene
Other products related to TRAF6 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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