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UGT1A1 (UDP Glucuronosyltransferase 1 Family, Polypeptide A1, UGT1A1)

Short Description: This gene encodes a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. This gene is part of a complex locus that encodes several UDP-glucuronosyltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes. Each of the remaining nine 5' exons may be spliced to the four common exons, resulting in nine proteins with different N-termini and identical C-termini. Each first exon encodes the substrate binding site, and is regulated by its own promoter. The preferred substrate of this enzyme is bilirubin, although it also has moderate activity with simple phenols, flavones, and C18 steroids. Mutations in this gene result in Crigler-Najjar syndromes types I and II and in Gilbert syndrome. [provided by RefSeq, Jul 2008].
More information related to gene UGT1A1.

Products related to UGT1A1 Gene:

62 results

OriGene kn518663 gRNA + Cas9 GEEN Mammalian Expression Vector pCas-Guide Ampicillin U6 Promoter Myc-DYKDDDDK Tag Transient
Type:
gRNA + Cas9
Application:
Genome Editing with Engineered Nucleases
Gene:
UDP Glucuronosyltransferase 1 Family, Polypeptide A1 (UGT1A1)
Species:
Mouse
Vector type:
Mammalian Expression Vector
Vector backbone:
pCas-Guide
Resistance Gene:
Ampicillin
Promoter:
U6 Promoter, Enhanced CMV Promoter
Fusion Tag:
Myc-DYKDDDDK Tag
Expression:
Transient
Catalog No. ABIN3259574
$1,640.43
Plus shipping costs $50.00
1 kit
Shipping to: United States
Delivery in 21 to 22 Business Days
OriGene kn413439 gRNA + Cas9 GEEN Mammalian Expression Vector pCas-Guide Ampicillin U6 Promoter Myc-DYKDDDDK Tag Transient
Type:
gRNA + Cas9
Application:
Genome Editing with Engineered Nucleases
Gene:
UDP Glucuronosyltransferase 1 Family, Polypeptide A1 (UGT1A1)
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pCas-Guide
Resistance Gene:
Ampicillin
Promoter:
U6 Promoter, Enhanced CMV Promoter
Fusion Tag:
Myc-DYKDDDDK Tag
Expression:
Transient
Catalog No. ABIN3259573
$1,640.43
Plus shipping costs $50.00
1 kit
Shipping to: United States
Delivery in 21 to 22 Business Days
  • Type
    • Plasmid
    • Primer
  • Supplier
    • antibodies-online
    • OriGene
    • GenScript
    • ProteoGenix
  • Reactivity
    • Human
    • Mouse
    • Rat
  • Application
    • Protein Expression (PExp)
    • Cloning (Clon)
    • RNA Interference (RNAi)
    • Genome Editing with Engineered Nucleases (GEEN)
  • Conjugate
    • Un-conjugated
    • GFP tag
    • His tag
    • Myc-DYKDDDDK Tag
    • His-GST
    • His-MBP
    • HA tag
    • RFP tag
    • DYKDDDDK Tag
  • Vector Backbone
    • pLenti-U6-sgRNA-PGK-Neo
    • pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
    • pCMV6-Entry
    • pPB-His-GST
    • pPB-His-MBP
    • pGFP-C-shLenti
    • pGFP-V-RS
    • pORF
    • pPB-N-His
    • pPM-C-HA
    • pPM-C-His
    • pRFP-C-RS
    • pRS
    • pCas-Guide
    • pLenti-C-Myc-DDK
    • pLenti-C-mGFP
    • pCMV6-AC-GFP
    • pCMV6-XL4
    • pDONR223
    • pcDNA3.1+C-(K)-DYK
  • Vector
    • Lentiviral Vector
    • Mammalian Expression Vector
    • Bacterial Expression Vector
    • Retroviral Vector
    • Cloning Vector
    • Gateway Cloning Vector
  • Insert
    • cDNA
    • ORF
    • shRNA
    • gRNA + Cas9
    • gRNA
  • Type of Oligonucleotide
    • siRNA Oligo
  • Bacterial Resistance
    • Kanamycin
    • Ampicillin
    • Chloramphenicol
    • Spectinomycin
  • Expression Type
    • Transient
    • Stable
  • Selectable Marker
    • Puromycin
    • Neomycin
  • Promoter
    • U6 Promoter
    • CMV Promoter
    • T7 Promoter
    • Enhanced CMV Promoter
    • PGK Promoter
    • SFFV Promoter
  • Format
    • Lyophilized
    • Liquid
    • Viral Particles

Synonyms and alternative names related to UGT1A1

  • UDP glucuronosyltransferase family 1 member A1 (UGT1A1)
  • UDP glucuronosyltransferase 1 family, polypeptide A1 (Ugt1a1)
  • UDP glucuronosyltransferase 1 family, polypeptide A1 (UGT1A1)
  • UDP-glucuronosyltransferase 1-1 (LOC100065342)
  • UDP-glucuronosyltransferase (LOC100125517)
  • UDP-glucuronosyltransferase 1-1 (LOC100229734)
  • UDP-glucuronosyltransferase 1-6 (LOC100405984)
  • UDP-glucuronosyltransferase 1-1 (LOC100511479)
  • UDP glucuronosyltransferase family 1 member A1 (Ugt1a1)
  • UDP glucuronosyltransferase 1 family polypeptide a1 (ugt1a1)
  • BILIQTL1
  • GNT1
  • Gnt1
  • HUG-BR1
  • UDPGT
  • Udpgt
  • Udpgt-1a
  • UDPGT 1-1
  • UGT1
  • Ugt1
  • UGT1A
  • UGT1A01
  • UgtBr1
  • zgc:123097

Gene-IDs for different species

Protein level used designations for UGT1A1

  • UDP glycosyltransferase 1 family, polypeptide A1
  • UDP-glucuronosyltransferase 1-1
  • UDP-glucuronosyltransferase 1-A
  • UDP-glucuronosyltransferase 1A1
  • UGT-1A
  • UGT1*1
  • UGT1-01
  • UGT1.1
  • bilirubin UDP-glucuronosyltransferase 1-1
  • bilirubin UDP-glucuronosyltransferase isozyme 1
  • bilirubin-specific UDPGT isozyme 1
  • UDP-glucuronosyltransferase 1 family, member 1
  • UDP-glucuronosyltransferase 1 family, polypeptide A1
  • UDPGT
  • UDP glucuronosyltransferase 1 family, polypeptide A1
  • uridine diphosphate glucuronosyltransferase 1A1
  • UDP-glucuronosyltransferase UGT1A01
  • UDP glucuronosyltransferase 1 family polypeptide A1
  • UDP glycosyl transferase 1A1
  • UDP-glucuronosyltransferase 1-1-like
  • B1
  • UDP-glucuronosyltransferase 1 family member 1
Other products related to UGT1A1 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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