UIMC1 (Ubiquitin Interaction Motif Containing 1, UIMC1)
Short Description: Ubiquitin-binding protein that specifically recognizes and binds 'Lys-63'-linked ubiquitin. Plays a central role in the BRCA1-A complex by specifically binding 'Lys-63'-linked ubiquitinated histones H2A and H2AX at DNA lesions sites, leading to target the BRCA1-BARD1 heterodimer to sites of DNA damage at double-strand breaks (DSBs). The BRCA1-A complex also possesses deubiquitinase activity that specifically removes 'Lys-63'-linked ubiquitin on histones H2A and H2AX. Also weakly binds monoubiquitin but with much less affinity than 'Lys-63'-linked ubiquitin. May interact with monoubiquitinated histones H2A and H2B\; the relevance of such results is however unclear in vivo. Does not bind Lys-48'-linked ubiquitin. May indirectly Act as a transcriptional repressor by inhibiting the interaction of NR6A1 with the corepressor NCOR1 (By similarity).
More information related to gene UIMC1.
More information related to gene UIMC1.
Products related to UIMC1 Gene:
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59 results
ORF
Clon
Gateway Cloning Vector
pDONR223
Spectinomycin
unconjugated
Catalog No. ABIN5317757
$235.38
Plus shipping costs $50.00
2 μg
Shipping to:
United States
Delivery in 15 to 19 Business Days
OriGene mc227747
cDNA
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
Enhanced CMV Promoter
unconjugated
Transient
1
- Type:
- cDNA
- Application:
- Protein Expression
- Gene:
- Ubiquitin Interaction Motif Containing 1 (UIMC1)
- NCBI Accession:
- NM_001293660,NP_001280589
- Species:
- Mouse
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-Entry
- Resistance Gene:
- Kanamycin
- Selection Marker:
- Neomycin
- Promoter:
- Enhanced CMV Promoter
- Expression:
- Transient
Catalog No. ABIN3338748
$497.97
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 16 to 17 Business Days
ORF
PExp
Mammalian Expression Vector
pcDNA3.1+C-(K)-DYK
Ampicillin
CMV Promoter
DYKDDDDK Tag
Transient
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Ubiquitin Interaction Motif Containing 1 (UIMC1)
- NCBI Accession:
- NM_001199297
- Gene ID:
- 51720 (Human, UIMC1)
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pcDNA3.1+C-(K)-DYK
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Neomycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- DYKDDDDK Tag
- Expression:
- Transient, Stable
Catalog No. ABIN4942069
$559.00
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 31 to 32 Business Days
OriGene sr419584
RNAi
UIMC1
Species: Mouse
HPLC purified
- Application:
- RNA Interference
- Gene:
- Ubiquitin Interaction Motif Containing 1
- Species:
- Mouse
- Purification:
- HPLC purified
Catalog No. ABIN3262763
$512.82
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 16 to 17 Business Days
OriGene sr506128
RNAi
UIMC1
Species: Rat
HPLC purified
- Application:
- RNA Interference
- Gene:
- Ubiquitin Interaction Motif Containing 1
- Species:
- Rat
- Purification:
- HPLC purified
Catalog No. ABIN3355790
$512.82
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 16 to 17 Business Days
OriGene sr309932
RNAi
UIMC1
Species: Human
HPLC purified
- Application:
- RNA Interference
- Gene:
- Ubiquitin Interaction Motif Containing 1
- Species:
- Human
- Purification:
- HPLC purified
Catalog No. ABIN3285968
$512.82
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 16 to 17 Business Days
OriGene rc202823
ORF
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
CMV Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Ubiquitin Interaction Motif Containing 1 (UIMC1)
- NCBI Accession:
- NM_016290,NP_057374
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-Entry
- Resistance Gene:
- Kanamycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN5368935
$583.11
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 16 to 17 Business Days
OriGene sc114384
cDNA
PExp
Mammalian Expression Vector
pCMV6-XL5
Ampicillin
Enhanced CMV Promoter
unconjugated
Transient
1
- Type:
- cDNA
- Application:
- Protein Expression
- Gene:
- Ubiquitin Interaction Motif Containing 1 (UIMC1)
- NCBI Accession:
- NM_016290,NP_057374
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-XL5
- Resistance Gene:
- Ampicillin
- Promoter:
- Enhanced CMV Promoter, T7 Promoter
- Expression:
- Transient
Catalog No. ABIN3387613
$652.41
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 4 to 9 Business Days
OriGene tg307008
shRNA
RNAi
Retroviral Vector
pGFP-V-RS
Kanamycin
U6 Promoter
GFP tag
Transient
1
- Type:
- shRNA
- Application:
- RNA Interference
- Gene:
- Ubiquitin Interaction Motif Containing 1 (UIMC1)
- Species:
- Human
- Vector type:
- Retroviral Vector
- Vector backbone:
- pGFP-V-RS
- Resistance Gene:
- Kanamycin
- Selection Marker:
- Puromycin
- Promoter:
- U6 Promoter
- Fusion Tag:
- GFP tag
- Expression:
- Transient, Stable
Catalog No. ABIN3731894
$707.85
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 16 to 17 Business Days
OriGene tf513847
shRNA
RNAi
Retroviral Vector
pRFP-C-RS
Chloramphenicol
U6 Promoter
RFP tag
Transient
1
- Type:
- shRNA
- Application:
- RNA Interference
- Gene:
- Ubiquitin Interaction Motif Containing 1 (UIMC1)
- Species:
- Mouse
- Vector type:
- Retroviral Vector
- Vector backbone:
- pRFP-C-RS
- Resistance Gene:
- Chloramphenicol
- Selection Marker:
- Puromycin
- Promoter:
- U6 Promoter
- Fusion Tag:
- RFP tag
- Expression:
- Transient, Stable
Catalog No. ABIN3676149
$707.85
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 16 to 17 Business Days
Synonyms and alternative names related to UIMC1
- ubiquitin interaction motif containing 1 (UIMC1)
- ubiquitin interaction motif containing 1 (Uimc1)
- 9430016E08Rik
- D330018D10Rik
- D630032M02Rik
- RAP80
- RGD1307009
- RIP110
- Rxrip110
- UIMC1
- X2HRIP110
Gene-IDs for different species
Protein level used designations for UIMC1
- ubiquitin interaction motif containing 1
- BRCA1-A complex subunit RAP80-like
- BRCA1-A complex subunit RAP80
- receptor-associated protein 80
- ubiquitin interaction motif-containing protein 1
- receptor associated protein 80
- retinoid X receptor-interacting protein 110
- retinoid x receptor interacting protein
- retinoid X receptor interacting protein 110
Proteomics products related to UIMC1 Gene
Other products related to UIMC1 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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