USP8 (Ubiquitin Specific Peptidase 8, USP8)
Short Description: Hydrolase that can remove conjugated ubiquitin from proteins and therefore plays an important regulatory role at the level of protein turnover by preventing degradation. Converts both 'Lys-48' an 'Lys-63'-linked ubiquitin chains. Catalytic activity is enhanced in the M phase. Involved in cell proliferation. Required to enter into S phase in response to serum stimulation. May regulate T-cell anergy mediated by RNF128 via the formation of a complex containing RNF128 and OTUB1. Probably regulates the stability of STAM2 and RASGRF1. Regulates endosomal ubiquitin dynamics, cargo sorting, membrane traffic at early endosomes, and maintenance of ESCRT-0 stability. The level of protein ubiquitination on endosomes is essential for maintaining the morphology of the organelle. Deubiquitinates EPS15 and controles tyrosine kinase stability. Removes conjugated ubiquitin from EGFR thus regulating EGFR degradation and downstream MAPK signaling. Involved in acrosome biogenesis through interaction with the spermatid ESCRT-0 complex and microtubules. Deubiquitinates BIRC6/bruce and KIF23/MKLP1.
More information related to gene USP8.
More information related to gene USP8.
Products related to USP8 Gene:
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72 results
OriGene tr505445
shRNA
RNAi
Retroviral Vector
pRS
Ampicillin
U6 Promoter
unconjugated
Transient
1
- Type:
- shRNA
- Application:
- RNA Interference
- Gene:
- Ubiquitin Specific Peptidase 8 (USP8)
- Species:
- Mouse
- Vector type:
- Retroviral Vector
- Vector backbone:
- pRS
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Puromycin
- Promoter:
- U6 Promoter
- Expression:
- Transient, Stable
Catalog No. ABIN3537780
$874.17
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 16 to 17 Business Days
OriGene mc223467
cDNA
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
Enhanced CMV Promoter
unconjugated
Transient
1
- Type:
- cDNA
- Application:
- Protein Expression
- Gene:
- Ubiquitin Specific Peptidase 8 (USP8)
- NCBI Accession:
- NM_019729,NP_062703
- Species:
- Mouse
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-Entry
- Resistance Gene:
- Kanamycin
- Selection Marker:
- Neomycin
- Promoter:
- Enhanced CMV Promoter
- Expression:
- Transient
Catalog No. ABIN3339003
$931.59
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 36 to 37 Business Days
OriGene rc239882
ORF
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
CMV Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Ubiquitin Specific Peptidase 8 (USP8)
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-Entry
- Resistance Gene:
- Kanamycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN5460717
$959.31
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 21 to 22 Business Days
OriGene sc337776
cDNA
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
Enhanced CMV Promoter
unconjugated
Transient
1
- Type:
- cDNA
- Application:
- Protein Expression
- Gene:
- Ubiquitin Specific Peptidase 8 (USP8)
- NCBI Accession:
- NM_001283049,NP_001269978
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-Entry
- Resistance Gene:
- Kanamycin
- Selection Marker:
- Neomycin
- Promoter:
- Enhanced CMV Promoter
- Expression:
- Transient
Catalog No. ABIN3339005
$960.30
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 21 to 22 Business Days
OriGene rc216926
ORF
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
CMV Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Ubiquitin Specific Peptidase 8 (USP8)
- NCBI Accession:
- NM_005154,NP_005145
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-Entry
- Resistance Gene:
- Kanamycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN5460714
$963.27
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 8 to 11 Business Days
OriGene rc226336
ORF
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
CMV Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Ubiquitin Specific Peptidase 8 (USP8)
- NCBI Accession:
- NM_001128610,NP_001122082
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-Entry
- Resistance Gene:
- Kanamycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN5460715
$963.27
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 16 to 17 Business Days
OriGene sc125502
cDNA
PExp
Mammalian Expression Vector
pCMV6-XL4
Ampicillin
Enhanced CMV Promoter
unconjugated
Transient
1
- Type:
- cDNA
- Application:
- Protein Expression
- Gene:
- Ubiquitin Specific Peptidase 8 (USP8)
- NCBI Accession:
- NM_005154,NP_005145
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-XL4
- Resistance Gene:
- Ampicillin
- Promoter:
- Enhanced CMV Promoter, T7 Promoter
- Expression:
- Transient
Catalog No. ABIN3380593
$964.26
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 16 to 17 Business Days
OriGene sc323258
cDNA
PExp
Mammalian Expression Vector
pCMV6-XL5
Ampicillin
Enhanced CMV Promoter
unconjugated
Transient
1
- Type:
- cDNA
- Application:
- Protein Expression
- Gene:
- Ubiquitin Specific Peptidase 8 (USP8)
- NCBI Accession:
- NM_001128610,NP_001122082
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-XL5
- Resistance Gene:
- Ampicillin
- Promoter:
- Enhanced CMV Promoter, T7 Promoter
- Expression:
- Transient
Catalog No. ABIN3393001
$964.26
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 16 to 17 Business Days
OriGene tl308453
shRNA
RNAi
Lentiviral Vector
pGFP-C-shLenti
Chloramphenicol
U6 Promoter
GFP tag
Transient
1
- Type:
- shRNA
- Application:
- RNA Interference
- Gene:
- Ubiquitin Specific Peptidase 8 (USP8)
- Species:
- Human
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pGFP-C-shLenti
- Resistance Gene:
- Chloramphenicol
- Selection Marker:
- Puromycin
- Promoter:
- U6 Promoter
- Fusion Tag:
- GFP tag
- Expression:
- Transient, Stable
Catalog No. ABIN3753665
$1,002.87
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 16 to 17 Business Days
OriGene tl705081
shRNA
RNAi
Lentiviral Vector
pGFP-C-shLenti
Chloramphenicol
U6 Promoter
GFP tag
Transient
1
- Type:
- shRNA
- Application:
- RNA Interference
- Gene:
- Ubiquitin Specific Peptidase 8 (USP8)
- Species:
- Rat
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pGFP-C-shLenti
- Resistance Gene:
- Chloramphenicol
- Selection Marker:
- Puromycin
- Promoter:
- U6 Promoter
- Fusion Tag:
- GFP tag
- Expression:
- Transient, Stable
Catalog No. ABIN3513233
$1,002.87
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 16 to 17 Business Days
Synonyms and alternative names related to USP8
- ubiquitin carboxyl-terminal hydrolase 8 (LOC9310109)
- ubiquitin carboxyl-terminal hydrolase 8 (MGYG_00369)
- ubiquitin specific peptidase 8 (USP8)
- ubiquitin specific peptidase 8 (Usp8)
- AI574262
- AW557536
- HumORF8
- mKIAA0055
- UBPY
- Ubpy
Gene-IDs for different species
Protein level used designations for USP8
- ubiquitin carboxyl-terminal hydrolase 8
- ubiquitin-specific-processing protease 8
- ubiquitin specific peptidase 8
- ubiquitin carboxyl-terminal hydrolase 8-like
- deubiquitinating enzyme 8
- hUBPy
- ubiquitin isopeptidase Y
- ubiquitin specific protease 8
- ubiquitin thioesterase 8
- ubiquitin thiolesterase 8
- putative deubiquitinating enzyme
Proteomics products related to USP8 Gene
Other products related to USP8 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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