XBP1 (X-Box Binding Protein 1, XBP1)
Short Description: This gene encodes a transcription factor that regulates MHC class II genes by binding to a promoter element referred to as an X box. This gene product is a bZIP protein, which was also identified as a cellular transcription factor that binds to an enhancer in the promoter of the T cell leukemia virus type 1 promoter. It may increase expression of viral proteins by acting as the DNA binding partner of a viral transactivator. It has been found that upon accumulation of unfolded proteins in the endoplasmic reticulum (ER), the mRNA of this gene is processed to an active form by an unconventional splicing mechanism that is mediated by the endonuclease inositol-requiring enzyme 1 (IRE1). The resulting loss of 26 nt from the spliced mRNA causes a frame-shift and an isoform XBP1(S), which is the functionally active transcription factor. The isoform encoded by the unspliced mRNA, XBP1(U), is constitutively expressed, and thought to function as a negative feedback regulator of XBP1(S), which shuts off transcription of target genes during the recovery phase of ER stress. A pseudogene of XBP1 has been identified and localized to chromosome 5. [provided by RefSeq, Jul 2008].
More information related to gene XBP1.
More information related to gene XBP1.
Products related to XBP1 Gene:
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72 results
OriGene kn519483
gRNA + Cas9
GEEN
Mammalian Expression Vector
pCas-Guide
Ampicillin
U6 Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- gRNA + Cas9
- Application:
- Genome Editing with Engineered Nucleases
- Gene:
- X-Box Binding Protein 1 (XBP1)
- Species:
- Mouse
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCas-Guide
- Resistance Gene:
- Ampicillin
- Promoter:
- U6 Promoter, Enhanced CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN3260933
$1,640.43
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 21 to 22 Business Days
OriGene kn201959
gRNA + Cas9
GEEN
Mammalian Expression Vector
pCas-Guide
Ampicillin
U6 Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- gRNA + Cas9
- Application:
- Genome Editing with Engineered Nucleases
- Gene:
- X-Box Binding Protein 1 (XBP1)
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCas-Guide
- Resistance Gene:
- Ampicillin
- Promoter:
- U6 Promoter, Enhanced CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN3260932
$1,640.43
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 21 to 22 Business Days
Synonyms and alternative names related to XBP1
- X-box binding protein 1 (xbp1)
- X-box binding protein 1 (XBP1)
- X-box binding protein 1 (Xbp1)
- X-box binding protein 1 L homeolog (xbp1.L)
- cb918
- D11Ertd39e
- HTF
- id:ibd1195
- TREB-5
- treb5
- TREB5
- trebf
- wu:fb02h05
- wu:fb63f10
- XBP-1
- xbp1
- xbp1a
- xbp1b
- XBP1P1
- xbp2
- XBP2
- XBPP1
- xXBP1
Gene-IDs for different species
Protein level used designations for XBP1
- X-box binding protein 1 pseudogene 1
- X-box binding protein pseudogene 1
- X-box binding protein 1
- X-box-binding protein 1
- tax-responsive element-binding protein 5
- tax-responsive element-binding protein 5 homolog
- XBP-1
- hepatocarcinogenesis-related transcription factor
- X-box binding protein 1B
Proteomics products related to XBP1 Gene
Other products related to XBP1 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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