Human SLC39A8 cDNA Clone in Mammalian Expression Vector
This is a Solute Carrier Family 39 (Zinc Transporter), Member 8 plasmid from OriGene - 2 times cited - with cDNA insert cloned into Mammalian Expression VectorpCMV6-AC. Insert length: not_set. Transient, Stable expression. Suitable for PExp.
Bacterial selection: Ampicillin.
1 image
(2 references)
Catalog No. ABIN3318288
Supplier Product No.: sc320928
$452.43
Plus shipping costs $50.00
10 μg
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Quick Overview for Human SLC39A8 cDNA Clone in Mammalian Expression Vector (ABIN3318288)
Gene
SLC39A8
(Solute Carrier Family 39 (Zinc Transporter), Member 8 (SLC39A8))
Application
Protein Expression (PExp)
Insert
cDNA
Vector
Mammalian Expression Vector
Vector Backbone
pCMV6-AC
Promoter
Enhanced CMV Promoter
Bacterial Resistance
Ampicillin
Expression Type
Transient, Stable
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Species
- Human
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Supplier Product No.
- sc320928
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Supplier
- OriGene
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Purpose
- Untagged full-length cDNA clone from Human SLC39A8 is ideal for over-expression of native protein for functional studies.
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Specificity
- Restriction Site: EcoRI-XhoI
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Characteristics
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- These cDNA clones are isolated from full-length cDNA libraries and usually contain the coding sequence as well as the untranslated regions (UTRs) of the mRNA transcript appropriate to the library from which they were isolated.
- These cDNA clones are ideal for over-expression of native proteins for functional studies. Provided as 10 μg transfection-ready plasmids.
- Every lot of primer is tested to provide clean sequencing of cDNA clones.
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Purification
- The DNAs were purified using PowerPrep HP Plasmid isolation kits for transfection ready plasmids.
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Components
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- The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA.
- The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials.
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Selectable Marker
- Neomycin
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Sequencing Primer
- VP1.5 (forward) 5'GGACTTTCCAAAATGTCG 3', XL39 (reverse) 5'ATTAGGACAAGGCTGGTGGG 3'
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Storage
- RT,-20 °C
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Storage Comment
- The lyophilized plasmid is stable for up to one year when stored at ambient temperature. Following dissolution in 100 μL dH2O, store at -20 °C. Lyophilized primers are stable for up to one year when stored at ambient temperature. Following dissolution in 10 μL dH2O, store at -20 °C.
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Expiry Date
- 12 months
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: "Zinc transporter ZIP8 (SLC39A8) and zinc influence IFN-gamma expression in activated human T cells." in: Journal of leukocyte biology, Vol. 86, Issue 2, pp. 337-48, (2009) (PubMed).
: "The human zinc transporter SLC39A8 (Zip8) is critical in zinc-mediated cytoprotection in lung epithelia." in: American journal of physiology. Lung cellular and molecular physiology, Vol. 294, Issue 6, pp. L1127-36, (2008) (PubMed).
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- SLC39A8 (Solute Carrier Family 39 (Zinc Transporter), Member 8 (SLC39A8))
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Alternative Name
- SLC39A8
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Background
- This gene encodes a member of the SLC39 family of solute-carrier genes, which show structural characteristics of zinc transporters. The encoded protein is glycosylated and found in the plasma membrane and mitochondria, and functions in the cellular import of zinc at the onset of inflammation. It is also thought to be the primary transporter of the toxic cation cadmium, which is found in cigarette smoke. Multiple transcript variants encoding different isoforms have been found for this gene. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. [provided by RefSeq, Oct 2008].Transcript Variant: This variant (1) encodes the longest isoform (a).
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NCBI Accession
- NM_022154, NP_071437
Target
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