Human SLCO2B1 cDNA Clone in Mammalian Expression Vector
This is a Solute Carrier Organic Anion Transporter Family, Member 2B1 plasmid from OriGene - 4 times cited - with cDNA insert cloned into Mammalian Expression VectorpCMV6-XL4. Insert length: 4130 bp. Transient expression. Suitable for PExp.
Bacterial selection: Ampicillin.
1 image
(4 references)
Catalog No. ABIN3380068
Supplier Product No.: sc115618
$965.25
Plus shipping costs $50.00
10 μg
Shipping to:
United States
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Quick Overview for Human SLCO2B1 cDNA Clone in Mammalian Expression Vector (ABIN3380068)
Gene
SLCO2B1
(Solute Carrier Organic Anion Transporter Family, Member 2B1 (SLCO2B1))
Application
Protein Expression (PExp)
Insert
cDNA
Vector
Mammalian Expression Vector
Vector Backbone
pCMV6-XL4
Promoter
Enhanced CMV Promoter, T7 Promoter
Bacterial Resistance
Ampicillin
Expression Type
Transient
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Species
- Human
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Supplier Product No.
- sc115618
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Supplier
- OriGene
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Purpose
- Untagged full-length cDNA clone from Human SLCO2B1 is ideal for over-expression of native protein for functional studies.
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Specificity
- Restriction Site: NotI-NotI
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Characteristics
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- These cDNA clones are isolated from full-length cDNA libraries and usually contain the coding sequence as well as the untranslated regions (UTRs) of the mRNA transcript appropriate to the library from which they were isolated.
- These cDNA clones are ideal for over-expression of native proteins for functional studies. Provided as 10 μg transfection-ready plasmids.
- Every lot of primer is tested to provide clean sequencing of cDNA clones.
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Purification
- The DNAs were purified using PowerPrep HP Plasmid isolation kits for transfection ready plasmids.
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Components
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- The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA.
- The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials.
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Insert Length
- 4130 bp
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Sequencing Primer
- VP1.5 (forward) 5'GGACTTTCCAAAATGTCG 3', XL39 (reverse) 5'ATTAGGACAAGGCTGGTGGG 3'
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Storage
- RT,-20 °C
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Storage Comment
- The lyophilized plasmid is stable for up to one year when stored at ambient temperature. Following dissolution in 100 μL dH2O, store at -20 °C. Lyophilized primers are stable for up to one year when stored at ambient temperature. Following dissolution in 10 μL dH2O, store at -20 °C.
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Expiry Date
- 12 months
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: "Association of SLCO2B1 Genotypes With Time to Progression and Overall Survival in Patients Receiving Androgen-Deprivation Therapy for Prostate Cancer." in: Journal of clinical oncology : official journal of the American Society of Clinical Oncology, Vol. 34, Issue 4, pp. 352-9, (2016) (PubMed).
: "Role of OATP transporters in steroid uptake by prostate cancer cells in vivo." in: Prostate cancer and prostatic diseases, (2016) (PubMed).
: "Mechanisms of pH-gradient driven transport mediated by organic anion polypeptide transporters." in: American journal of physiology. Cell physiology, Vol. 296, Issue 3, pp. C570-82, (2009) (PubMed).
: "Interaction of macrolide antibiotics with intestinally expressed human and rat organic anion-transporting polypeptides." in: Drug metabolism and disposition: the biological fate of chemicals, Vol. 37, Issue 12, pp. 2375-82, (2009) (PubMed).
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- SLCO2B1 (Solute Carrier Organic Anion Transporter Family, Member 2B1 (SLCO2B1))
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Alternative Name
- SLCO2B1
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Background
- This locus encodes a member of the organic anion-transporting polypeptide family of membrane proteins. The protein encoded by this locus may function in regulation of placental uptake of sulfated steroids. Alternatively spliced transcript variants have been described. [provided by RefSeq, Nov 2010].Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1).
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NCBI Accession
- NM_007256, NP_009187
Target
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