Human FCGR2B cDNA Clone in Mammalian Expression Vector
This is a Fc Fragment of IgG, Low Affinity IIb, Receptor (CD32) plasmid from OriGene - 2 times cited - with cDNA insert cloned into Mammalian Expression VectorpCMV6-XL5. Insert length: 1600 bp. Transient expression. Suitable for PExp.
Bacterial selection: Ampicillin.
1 image
(2 references)
Catalog No. ABIN3389634
Supplier Product No.: sc128159
$445.50
Plus shipping costs $50.00
10 μg
Shipping to:
United States
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Quick Overview for Human FCGR2B cDNA Clone in Mammalian Expression Vector (ABIN3389634)
Gene
FCGR2B
(Fc Fragment of IgG, Low Affinity IIb, Receptor (CD32) (FCGR2B))
Application
Protein Expression (PExp)
Insert
cDNA
Vector
Mammalian Expression Vector
Vector Backbone
pCMV6-XL5
Promoter
Enhanced CMV Promoter, T7 Promoter
Bacterial Resistance
Ampicillin
Expression Type
Transient
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Species
- Human
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Supplier Product No.
- sc128159
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Supplier
- OriGene
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Purpose
- Untagged full-length cDNA clone from Human FCGR2B is ideal for over-expression of native protein for functional studies.
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Characteristics
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- These cDNA clones are isolated from full-length cDNA libraries and usually contain the coding sequence as well as the untranslated regions (UTRs) of the mRNA transcript appropriate to the library from which they were isolated.
- These cDNA clones are ideal for over-expression of native proteins for functional studies. Provided as 10 μg transfection-ready plasmids.
- Every lot of primer is tested to provide clean sequencing of cDNA clones.
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Purification
- The DNAs were purified using PowerPrep HP Plasmid isolation kits for transfection ready plasmids.
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Components
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- The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA.
- The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials.
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Insert Length
- 1600 bp
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Sequencing Primer
- VP1.5 (forward) 5'GGACTTTCCAAAATGTCG 3', XL39 (reverse) 5'ATTAGGACAAGGCTGGTGGG 3'
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Storage
- RT,-20 °C
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Storage Comment
- The lyophilized plasmid is stable for up to one year when stored at ambient temperature. Following dissolution in 100 μL dH2O, store at -20 °C. Lyophilized primers are stable for up to one year when stored at ambient temperature. Following dissolution in 10 μL dH2O, store at -20 °C.
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Expiry Date
- 12 months
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: "Human FcγRII cytoplasmic domains differentially influence antibody-mediated dengue virus infection." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 190, Issue 11, pp. 5659-65, (2013) (PubMed).
: "Anti-peptidoglycan antibodies and Fcγ receptors are the key mediators of inflammation in Gram-positive sepsis." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 189, Issue 5, pp. 2423-31, (2012) (PubMed).
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: "Human FcγRII cytoplasmic domains differentially influence antibody-mediated dengue virus infection." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 190, Issue 11, pp. 5659-65, (2013) (PubMed).
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- FCGR2B (Fc Fragment of IgG, Low Affinity IIb, Receptor (CD32) (FCGR2B))
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Alternative Name
- FCGR2B
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Background
- The protein encoded by this gene is a low affinity receptor for the Fc region of immunoglobulin gamma complexes. The encoded protein is involved in the phagocytosis of immune complexes and in the regulation of antibody production by B-cells. Variations in this gene may increase susceptibilty to systemic lupus erythematosus (SLE). Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2010].Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1).
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NCBI Accession
- NM_004001, NP_003992
Target
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