Human DNAJC19 ORF Clone in Mammalian Expression Vector (Myc-DYKDDDDK Tag)
Quick Overview for Human DNAJC19 ORF Clone in Mammalian Expression Vector (Myc-DYKDDDDK Tag) (ABIN5345347)
Gene
Fusion tag
Application
Insert
Vector
Vector Backbone
Promoter
Bacterial Resistance
Expression Type
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Species
- Human
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Supplier Product No.
- rc209910
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Supplier
- OriGene
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Purpose
- Mammalian Vector with ORF clone of Human DnaJ (Hsp40) homolog, subfamily C, member 19 (DNAJC19) transcript variant 1
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Specificity
- Restriction Site: SgfI-MluI
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Grade
- End-sequenced
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Components
- The ORF clone is ion-exchange column purified, transfection-ready dried plasmid DNA, and shipped with 2 vector sequencing primers.
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Insert Length
- 351 bp
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Sequencing Primer
- VP1.5 (forward) 5'GGACTTTCCAAAATGTCG 3', XL39 (reverse) 5'ATTAGGACAAGGCTGGTGGG 3'
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Storage
- 4 °C/-20 °C
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- DNAJC19 (DnaJ (Hsp40) Homolog, Subfamily C, Member 19 (DNAJC19))
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Background
- The protein encoded by this gene is thought to be part of a complex involved in the ATP-dependent transport of transit peptide-containing proteins from the inner cell membrane to the mitochondrial matrix. Defects in this gene are a cause of 3-methylglutaconic aciduria type 5 (MGA5), also known as dilated cardiomyopathy with ataxia (DCMA). Alternative splicing of this gene results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 1, 2, 6, 10, 14 and 19.
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NCBI Accession
- NM_145261, NP_660304
Target
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