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Mouse LRP5 siRNA Oligo

RNAi LRP5 Species: Mouse HPLC purified
OriGene
Catalog No. ABIN3349919
Supplier Product No.: sr423069
$512.82
Plus shipping costs $50.00
1 kit
Shipping to: United States
Delivery in 4 to 9 Business Days

Quick Overview for Mouse LRP5 siRNA Oligo (ABIN3349919)

Gene

LRP5 (Low Density Lipoprotein Receptor-Related Protein 5 (LRP5))

Species

Mouse

Application

RNA Interference (RNAi)

Purification

HPLC purified
  • Supplier Product No.

    sr423069

    Supplier

    OriGene

    Oligo-Type

    siRNA Oligo

    Purpose

    siRNA (27 mer) kit with 3 gene-specific unique siRNA duplexes and negative control for gene knockdown.

    Brand

    Trilencer-27

    Sequence

    Available with shipment

    Components

    • Lrp5 (Mouse) - 3 unique 27mer siRNA duplexes - 2 nmol each
    • Trilencer-27 Universal Scrambled Negative Control siRNA Duplex - 2 nmol
    • RNAse free siRNA Duplex Resuspension Buffer - 2 ml
  • Application Notes

    • No. of transfections: Approximately 330 transfections/2nmol in 24-well plate under optimized conditions (final conc. 10 nM)
    • Quality Control: Tested by ESI-MS

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    • 2 nmoles of each duplex is provided (including the control duplex). Addition of 100 μL of RNase-free Duplex Buffer will result in 20 μM final concentration, vortex thoroughly and microfuge prior to use.
    • Heat to 94 °C for 2 minutes, remove from heat and allow tube to cool to room temperature. The oligos were dried in duplex form so heating may not be necessary, however following this protocol ensures that the contents will be fully duplexed.

    Storage

    -20 °C

    Storage Comment

    The dried duplexes can be stored at 4 °C. However, once reconstituted with dH2O, the plasmids must be stored at -20°C.

    Expiry Date

    12 months
  • Wehmeyer, Frank, Beckmann, Böttcher, Cromme, König, Fennen, Held, Paruzel, Hartmann, Stratis, Korb-Pap, Kamradt, Kramer, van den Berg, Kneissel, Pap, Dankbar: "Sclerostin inhibition promotes TNF-dependent inflammatory joint destruction." in: Science translational medicine, Vol. 8, Issue 330, pp. 330ra35, (2016) (PubMed).

  • Target

    LRP5 (Low Density Lipoprotein Receptor-Related Protein 5 (LRP5))

    Alternative Name

    Lrp5
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