ABCC8 (ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 8, ABCC8)
Short Description: The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions as a modulator of ATP-sensitive potassium channels and insulin release. Mutations and deficiencies in this protein have been observed in patients with hyperinsulinemic hypoglycemia of infancy, an autosomal recessive disorder of unregulated and high insulin secretion. Mutations have also been associated with non-insulin-dependent diabetes mellitus type II, an autosomal dominant disease of defective insulin secretion. Alternative splicing of this gene has been observed\; however, the transcript variants have not been fully described. [provided by RefSeq, Jul 2008].
More information related to gene ABCC8.
More information related to gene ABCC8.
Products related to ABCC8 Gene:
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OriGene sc338074
cDNA
PExp
Mammalian Expression Vector
pCMV6-XL6
Ampicillin
Enhanced CMV Promoter
unconjugated
Transient
1
- Type:
- cDNA
- Application:
- Protein Expression
- Gene:
- ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 8 (ABCC8)
- NCBI Accession:
- NM_001287174,NP_001274103
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-XL6
- Resistance Gene:
- Ampicillin
- Promoter:
- Enhanced CMV Promoter, SP6 Promoter
- Expression:
- Transient
Catalog No. ABIN3393929
$1,637.90
Plus shipping costs $50.00
10 μg
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United States
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Synonyms and alternative names related to ABCC8
- ATP binding cassette subfamily C member 8 (ABCC8)
- ATP-binding cassette, sub-family C (CFTR/MRP), member 8 (Abcc8)
- ATP binding cassette subfamily C member 8 (Abcc8)
- ABC36
- D930031B21Rik
- HHF1
- HI
- HRINS
- MRP8
- PHHI
- SUR
- Sur
- SUR1
- Sur1
- SUR1delta2
- TNDM2
Gene-IDs for different species
Protein level used designations for ABCC8
- ATP-binding cassette, sub-family C (CFTR/MRP), member 8
- ATP-binding cassette, sub-family C, member 8
- ATP-binding cassette sub-family C member 8
- ATP-binding cassette transporter sub-family C member 8
- sulfonylurea receptor (hyperinsulinemia)
- sulfonylurea receptor 1
- sulfonylurea receptor
- sulphonylurea receptor 1
Proteomics products related to ABCC8 Gene
Other products related to ABCC8 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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